{
  "data_id": "sys06",
  "generated_at": "2026-02-24T10:13:57.933616",
  "analyses": {
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      "unique_pathways": 27,
      "top_pathway": "IGF",
      "top_source": "Macrophages",
      "top_target": "Adipocytes"
    },
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      "total_tf_target_pairs": 158,
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        "GATA4": 31,
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        "STAT3": 16,
        "JUN": 14,
        "SOX9": 5,
        "RB1": 2,
        "CEBPB": 2,
        "NFKB1": 1
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    "coexp": {
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      "module_sizes": {
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        "7": 2,
        "4": 2,
        "5": 2,
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    },
    "deg": {
      "total_degs_tested": 1800,
      "significant_degs": 1763,
      "n_celltypes": 18,
      "top_upregulated": [
        {
          "names": "FABP4",
          "cell_type": "Adipocytes",
          "logfoldchanges": 10.944806098937988
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        {
          "names": "CIDEC",
          "cell_type": "Adipocytes",
          "logfoldchanges": 10.011892318725586
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        {
          "names": "PLIN1",
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          "logfoldchanges": 9.339682579040527
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        {
          "names": "C14orf180",
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        {
          "names": "GHR",
          "cell_type": "Adipocytes",
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    "enrichment": {
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      "kegg_pathways_found": 144,
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    "toppgene": {
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      "total_enrichments": 396
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    "motif": {
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    "disease": {
      "diseases_tested": 15,
      "significant_associations": 12,
      "top_diseases": [
        "Systemic lupus erythematosus",
        "Autism spectrum disorder",
        "Breast cancer",
        "Asthma",
        "Asthma"
      ]
    }
  }
}