🧬 Single-Cell Analysis Report
5799
Cell-Cell Interactions
342
TF-Target Pairs
1780
Significant DEGs
162
Enriched GO Terms
📡 Cell-Cell Communication Analysis
Analysis of intercellular communication via ligand-receptor interactions.
●
Identified 5799 significant ligand-receptor interactions
●
Top signaling pathway: IGF
●
Most active sender cell type: Macrophages
●
Most active receiver cell type: CD4+ T cells
Cell-Cell Communication Heatmap
Communication Network Graph
🧬 Gene Regulatory Network Analysis
Transcription factor regulatory relationships inferred from expression data.
●
Analyzed 90 transcription factors
●
Identified 342 TF-target gene relationships
Top Regulatory TFs
| Transcription Factor | Target Genes |
|---|---|
| RUNX1 | 84 |
| HNF4A | 76 |
| GATA3 | 68 |
| FOXA1 | 50 |
| GATA2 | 39 |
TF Activity Across Cell Types
Gene Regulatory Network
🔗 Gene Co-expression Network Analysis
WGCNA-style weighted gene co-expression network analysis.
●
Identified 30 co-expression modules
●
Analyzed 2000 highly variable genes
Module Dendrogram
Module-Cell Type Association
📊 Differential Expression Analysis
Cell type-specific marker genes and differential expression.
●
Tested 1900 gene-celltype combinations
●
Found 1780 significant DEGs
●
Across 18 cell types
Volcano Plot
Marker Gene Expression Heatmap
🎯 Functional Enrichment Analysis
GO and KEGG pathway enrichment analysis of DEGs.
●
Found 162 enriched GO terms
●
Found 144 enriched KEGG pathways
GO Enrichment
KEGG Pathway Enrichment
🏥 Disease Association Analysis
Enrichment analysis for disease-associated genes.
●
Tested 15 disease categories
●
Found 16 significant associations
Top Associated Diseases
●Systemic lupus erythematosus
●Breast cancer
●Autism spectrum disorder
●Autism spectrum disorder
●Rheumatoid arthritis
Disease Association Heatmap
Top Disease Associations