🧬 Single-Cell Analysis Report

Dataset: sys01tis16 | Generated: 2026-02-24 09:45

1073
Cell-Cell Interactions
19
TF-Target Pairs
739
Significant DEGs
72
Enriched GO Terms

📡 Cell-Cell Communication Analysis

Analysis of intercellular communication via ligand-receptor interactions.

● Identified 1073 significant ligand-receptor interactions
● Top signaling pathway: KIT
● Most active sender cell type: Purkinje cells
● Most active receiver cell type: Inhibitory neurons
Communication Heatmap
Cell-Cell Communication Heatmap
Communication Network
Communication Network Graph

🧬 Gene Regulatory Network Analysis

Transcription factor regulatory relationships inferred from expression data.

● Analyzed 90 transcription factors
● Identified 19 TF-target gene relationships

Top Regulatory TFs

Transcription FactorTarget Genes
RUNX18
FOXA25
SOX22
FOS1
STAT31
TF Activity Heatmap
TF Activity Across Cell Types
GRN Network
Gene Regulatory Network

🔗 Gene Co-expression Network Analysis

WGCNA-style weighted gene co-expression network analysis.

● Identified 30 co-expression modules
● Analyzed 2000 highly variable genes
Module Dendrogram
Module Dendrogram
Module Heatmap
Module-Cell Type Association

📊 Differential Expression Analysis

Cell type-specific marker genes and differential expression.

● Tested 800 gene-celltype combinations
● Found 739 significant DEGs
● Across 8 cell types
Volcano Plot
Volcano Plot
Marker Heatmap
Marker Gene Expression Heatmap

🎯 Functional Enrichment Analysis

GO and KEGG pathway enrichment analysis of DEGs.

● Found 72 enriched GO terms
● Found 64 enriched KEGG pathways
GO Enrichment
GO Enrichment
KEGG Enrichment
KEGG Pathway Enrichment

🏥 Disease Association Analysis

Enrichment analysis for disease-associated genes.

● Tested 15 disease categories
● Found 6 significant associations

Top Associated Diseases

●Autism spectrum disorder
●Autism spectrum disorder
●Parkinson disease
●Asthma
●Alzheimer disease
Disease Heatmap
Disease Association Heatmap
Disease Dotplot
Top Disease Associations