🧬 Single-Cell Analysis Report

Dataset: sys02tis02 | Generated: 2026-02-24 09:49

4526
Cell-Cell Interactions
463
TF-Target Pairs
1687
Significant DEGs
153
Enriched GO Terms

📡 Cell-Cell Communication Analysis

Analysis of intercellular communication via ligand-receptor interactions.

● Identified 4526 significant ligand-receptor interactions
● Top signaling pathway: CXCL
● Most active sender cell type: DN T cells
● Most active receiver cell type: Neutrophils
Communication Heatmap
Cell-Cell Communication Heatmap
Communication Network
Communication Network Graph

🧬 Gene Regulatory Network Analysis

Transcription factor regulatory relationships inferred from expression data.

● Analyzed 90 transcription factors
● Identified 463 TF-target gene relationships

Top Regulatory TFs

Transcription FactorTarget Genes
TP5350
GATA147
FOS43
RUNX237
MYC37
TF Activity Heatmap
TF Activity Across Cell Types
GRN Network
Gene Regulatory Network

🔗 Gene Co-expression Network Analysis

WGCNA-style weighted gene co-expression network analysis.

● Identified 30 co-expression modules
● Analyzed 2000 highly variable genes
Module Dendrogram
Module Dendrogram
Module Heatmap
Module-Cell Type Association

📊 Differential Expression Analysis

Cell type-specific marker genes and differential expression.

● Tested 1700 gene-celltype combinations
● Found 1687 significant DEGs
● Across 17 cell types
Volcano Plot
Volcano Plot
Marker Heatmap
Marker Gene Expression Heatmap

🎯 Functional Enrichment Analysis

GO and KEGG pathway enrichment analysis of DEGs.

● Found 153 enriched GO terms
● Found 136 enriched KEGG pathways
GO Enrichment
GO Enrichment
KEGG Enrichment
KEGG Pathway Enrichment

🏥 Disease Association Analysis

Enrichment analysis for disease-associated genes.

● Tested 15 disease categories
● Found 5 significant associations

Top Associated Diseases

●Systemic lupus erythematosus
●Multiple sclerosis
●Systemic lupus erythematosus
●Multiple sclerosis
●Alzheimer disease
Disease Heatmap
Disease Association Heatmap
Disease Dotplot
Top Disease Associations