🧬 Single-Cell Analysis Report
4784
Cell-Cell Interactions
631
TF-Target Pairs
1573
Significant DEGs
144
Enriched GO Terms
📡 Cell-Cell Communication Analysis
Analysis of intercellular communication via ligand-receptor interactions.
●
Identified 4784 significant ligand-receptor interactions
●
Top signaling pathway: CXCL
●
Most active sender cell type: Fibroblasts
●
Most active receiver cell type: Fibroblasts
Cell-Cell Communication Heatmap
Communication Network Graph
🧬 Gene Regulatory Network Analysis
Transcription factor regulatory relationships inferred from expression data.
●
Analyzed 90 transcription factors
●
Identified 631 TF-target gene relationships
Top Regulatory TFs
| Transcription Factor | Target Genes |
|---|---|
| FOS | 70 |
| CEBPB | 54 |
| LEF1 | 50 |
| EGR1 | 50 |
| GATA1 | 48 |
TF Activity Across Cell Types
Gene Regulatory Network
🔗 Gene Co-expression Network Analysis
WGCNA-style weighted gene co-expression network analysis.
●
Identified 30 co-expression modules
●
Analyzed 2000 highly variable genes
Module Dendrogram
Module-Cell Type Association
📊 Differential Expression Analysis
Cell type-specific marker genes and differential expression.
●
Tested 1600 gene-celltype combinations
●
Found 1573 significant DEGs
●
Across 16 cell types
Volcano Plot
Marker Gene Expression Heatmap
🎯 Functional Enrichment Analysis
GO and KEGG pathway enrichment analysis of DEGs.
●
Found 144 enriched GO terms
●
Found 128 enriched KEGG pathways
GO Enrichment
KEGG Pathway Enrichment
🏥 Disease Association Analysis
Enrichment analysis for disease-associated genes.
●
Tested 15 disease categories
●
Found 14 significant associations
Top Associated Diseases
●Systemic lupus erythematosus
●Type 2 diabetes
●Alzheimer disease
●Alzheimer disease
●Obesity
Disease Association Heatmap
Top Disease Associations