🧬 Single-Cell Analysis Report

Dataset: sys02tis05 | Generated: 2026-02-24 09:47

2197
Cell-Cell Interactions
72
TF-Target Pairs
977
Significant DEGs
99
Enriched GO Terms

📡 Cell-Cell Communication Analysis

Analysis of intercellular communication via ligand-receptor interactions.

● Identified 2197 significant ligand-receptor interactions
● Top signaling pathway: IGF
● Most active sender cell type: Macrophages
● Most active receiver cell type: Adipocytes
Communication Heatmap
Cell-Cell Communication Heatmap
Communication Network
Communication Network Graph

🧬 Gene Regulatory Network Analysis

Transcription factor regulatory relationships inferred from expression data.

● Analyzed 90 transcription factors
● Identified 72 TF-target gene relationships

Top Regulatory TFs

Transcription FactorTarget Genes
LEF136
SOX912
FOXA110
GATA43
TCF73
TF Activity Heatmap
TF Activity Across Cell Types
GRN Network
Gene Regulatory Network

🔗 Gene Co-expression Network Analysis

WGCNA-style weighted gene co-expression network analysis.

● Identified 30 co-expression modules
● Analyzed 2000 highly variable genes
Module Dendrogram
Module Dendrogram
Module Heatmap
Module-Cell Type Association

📊 Differential Expression Analysis

Cell type-specific marker genes and differential expression.

● Tested 1200 gene-celltype combinations
● Found 977 significant DEGs
● Across 11 cell types
Volcano Plot
Volcano Plot
Marker Heatmap
Marker Gene Expression Heatmap

🎯 Functional Enrichment Analysis

GO and KEGG pathway enrichment analysis of DEGs.

● Found 99 enriched GO terms
● Found 88 enriched KEGG pathways
GO Enrichment
GO Enrichment
KEGG Enrichment
KEGG Pathway Enrichment

🏥 Disease Association Analysis

Enrichment analysis for disease-associated genes.

● Tested 15 disease categories
● Found 11 significant associations

Top Associated Diseases

●Systemic lupus erythematosus
●Schizophrenia
●Multiple sclerosis
●Systemic lupus erythematosus
●Autism spectrum disorder
Disease Heatmap
Disease Association Heatmap
Disease Dotplot
Top Disease Associations