🧬 Single-Cell Analysis Report
2551
Cell-Cell Interactions
93
TF-Target Pairs
1269
Significant DEGs
117
Enriched GO Terms
📡 Cell-Cell Communication Analysis
Analysis of intercellular communication via ligand-receptor interactions.
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Identified 2551 significant ligand-receptor interactions
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Top signaling pathway: KIT
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Most active sender cell type: Podocytes
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Most active receiver cell type: Intercalated cells
Cell-Cell Communication Heatmap
Communication Network Graph
🧬 Gene Regulatory Network Analysis
Transcription factor regulatory relationships inferred from expression data.
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Analyzed 90 transcription factors
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Identified 93 TF-target gene relationships
Top Regulatory TFs
| Transcription Factor | Target Genes |
|---|---|
| HNF4A | 42 |
| GATA3 | 34 |
| RUNX1 | 7 |
| FOS | 2 |
| RB1 | 2 |
TF Activity Across Cell Types
Gene Regulatory Network
🔗 Gene Co-expression Network Analysis
WGCNA-style weighted gene co-expression network analysis.
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Identified 30 co-expression modules
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Analyzed 2000 highly variable genes
Module Dendrogram
Module-Cell Type Association
📊 Differential Expression Analysis
Cell type-specific marker genes and differential expression.
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Tested 1400 gene-celltype combinations
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Found 1269 significant DEGs
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Across 13 cell types
Volcano Plot
Marker Gene Expression Heatmap
🎯 Functional Enrichment Analysis
GO and KEGG pathway enrichment analysis of DEGs.
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Found 117 enriched GO terms
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Found 104 enriched KEGG pathways
GO Enrichment
KEGG Pathway Enrichment
🏥 Disease Association Analysis
Enrichment analysis for disease-associated genes.
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Tested 15 disease categories
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Found 10 significant associations
Top Associated Diseases
●Systemic lupus erythematosus
●Alzheimer disease
●Rheumatoid arthritis
●Multiple sclerosis
●Systemic lupus erythematosus
Disease Association Heatmap
Top Disease Associations