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Compare scores only within the same source species and an identical mapped gene set. Higher expression scores do not imply a pro-longevity direction, and these results do not establish causality.", "method_status": "validated_real", "schema_version": "2.0", "signature": { "coverage_status": "full", "denominator_gene_count": 15, "gene_set_id": "LACA-LONGEVITY-15-v1", "mapped_count": 15, "mapped_genes": [ "APOE", "FOXO3", "CETP", "SIRT6", "SIRT1", "SIRT3", "IGF1R", "KLOTHO", "APOC3", "IL6", "TERT", "IRS2", "TP53", "SHC1", "ACE" ], "mapping_method": "case_insensitive_exact", "missing_gene_handling": "none_missing", "missing_genes": [], "ortholog_inference": false, "score_basis": "all_curated_genes", "total_genes": 15 }, "status": "available" }