/*
 * LACA Human Immune Atlas — donor explorer
 * Sibling layer to css/human-immune-atlas.css.
 */
.hia-donor-page {
    --hia-cyan: #00f0ff;
    --hia-pink: #ff2e97;
    --hia-gold: #ffd700;
    --hia-green: #00ff88;
    --hia-surface: rgba(10, 1, 24, 0.74);
    --hia-surface-strong: rgba(5, 0, 15, 0.9);
    --hia-border: rgba(255, 255, 255, 0.11);
    --hia-muted: rgba(255, 255, 255, 0.68);
    --hia-soft: rgba(255, 255, 255, 0.5);
    --hia-copy: rgba(255, 255, 255, 0.76);
    --hia-width: 1380px;
    cursor: default;
    isolation: isolate;
}

.hia-donor-page,
.hia-donor-page * {
    box-sizing: border-box;
}

.hia-donor-page a,
.hia-donor-page button,
.hia-donor-page input {
    cursor: pointer;
}

.hia-donor-shell {
    width: min(var(--hia-width), 92%);
    margin: 0 auto;
    padding: 0 0 clamp(4rem, 7vw, 7rem);
}

.hia-donor-top {
    position: relative;
    padding: clamp(4rem, 8vw, 6.5rem) 0 clamp(1.8rem, 4vw, 3rem);
    display: grid;
    grid-template-columns: minmax(0, 1.12fr) minmax(320px, 0.88fr);
    gap: clamp(1.6rem, 4vw, 3.4rem);
    align-items: center;
}

.hia-donor-top::before {
    content: "";
    position: absolute;
    width: min(42vw, 540px);
    aspect-ratio: 1;
    right: -8%;
    top: 10%;
    z-index: -1;
    border-radius: 50%;
    background: radial-gradient(circle, rgba(0, 240, 255, 0.15), transparent 68%);
    filter: blur(14px);
    pointer-events: none;
}

.hia-breadcrumb {
    display: flex;
    flex-wrap: wrap;
    gap: 0.45rem;
    margin-bottom: 1rem;
    color: var(--hia-soft);
    font-family: "Azeret Mono", monospace;
    font-size: 0.68rem;
    letter-spacing: 0.06em;
}

.hia-breadcrumb a,
.hia-donor-link {
    color: var(--hia-cyan);
    text-decoration: none;
}

.hia-breadcrumb a:hover,
.hia-breadcrumb a:focus-visible,
.hia-donor-link:hover,
.hia-donor-link:focus-visible {
    color: #fff;
    text-decoration: underline;
    text-underline-offset: 3px;
}

.hia-donor-eyebrow {
    display: inline-flex;
    align-items: center;
    gap: 0.65rem;
    color: var(--hia-cyan);
    font-family: "Azeret Mono", "JetBrains Mono", monospace;
    font-size: 0.7rem;
    font-weight: 700;
    letter-spacing: 0.17em;
    text-transform: uppercase;
}

.hia-donor-eyebrow::before {
    content: "";
    width: 32px;
    height: 1px;
    background: currentColor;
    box-shadow: 0 0 14px currentColor;
}

.hia-donor-title h1 {
    max-width: 18ch;
    margin: 0.85rem 0 1rem;
    color: #fff;
    font-family: "Orbitron", sans-serif;
    font-size: clamp(2rem, 4.4vw, 3.6rem);
    font-weight: 900;
    letter-spacing: -0.04em;
    line-height: 1.06;
    overflow-wrap: anywhere;
}

.hia-donor-title h1 span {
    background: linear-gradient(118deg, #fff 0%, var(--hia-cyan) 48%, var(--hia-gold) 100%);
    -webkit-background-clip: text;
    background-clip: text;
    -webkit-text-fill-color: transparent;
}

.hia-donor-lede {
    max-width: 680px;
    margin: 0;
    color: var(--hia-copy);
    font-family: "Crimson Pro", Georgia, serif;
    font-size: clamp(1.05rem, 1.8vw, 1.32rem);
    font-weight: 300;
    line-height: 1.65;
}

.hia-donor-actions {
    display: flex;
    flex-wrap: wrap;
    gap: 0.7rem;
    margin-top: 1.5rem;
}

.hia-donor-pill {
    min-height: 44px;
    padding: 0.72rem 1.05rem;
    border: 1px solid rgba(0, 240, 255, 0.46);
    border-radius: 999px;
    display: inline-flex;
    align-items: center;
    justify-content: center;
    color: #fff;
    background: linear-gradient(135deg, rgba(0, 240, 255, 0.18), rgba(107, 70, 193, 0.2));
    box-shadow: 0 10px 34px rgba(0, 240, 255, 0.1);
    font-size: 0.72rem;
    font-weight: 700;
    letter-spacing: 0.06em;
    text-decoration: none;
    text-transform: uppercase;
    transition: transform 220ms ease, border-color 220ms ease, box-shadow 220ms ease;
}

.hia-donor-pill.secondary {
    border-color: rgba(255, 255, 255, 0.16);
    color: var(--hia-cyan);
    background: rgba(5, 0, 15, 0.48);
    box-shadow: none;
}

.hia-donor-pill:hover,
.hia-donor-pill:focus-visible {
    color: #fff;
    border-color: var(--hia-cyan);
    transform: translateY(-2px);
    outline: none;
}

.hia-donor-metrics {
    position: relative;
    padding: 1.15rem;
    border: 1px solid var(--hia-border);
    border-radius: 28px;
    overflow: hidden;
    background:
        linear-gradient(145deg, rgba(255, 255, 255, 0.055), transparent 38%),
        radial-gradient(circle at 50% 18%, rgba(0, 240, 255, 0.14), transparent 58%),
        var(--hia-surface);
    box-shadow: 0 24px 80px rgba(0, 0, 0, 0.27), inset 0 1px rgba(255, 255, 255, 0.08);
    backdrop-filter: blur(18px);
}

.hia-donor-metrics::after {
    content: "";
    position: absolute;
    inset: 16px;
    border: 1px solid rgba(255, 255, 255, 0.07);
    border-radius: 20px;
    pointer-events: none;
}

.hia-donor-metrics-head {
    position: relative;
    z-index: 1;
    margin: 0.2rem 0.25rem 0.85rem;
    color: var(--hia-cyan);
    font-family: "Azeret Mono", monospace;
    font-size: 0.68rem;
    font-weight: 700;
    letter-spacing: 0.16em;
    text-transform: uppercase;
}

.hia-donor-stats {
    position: relative;
    z-index: 1;
    display: grid;
    grid-template-columns: repeat(2, minmax(0, 1fr));
    gap: 0.65rem;
}

.hia-donor-stat {
    min-height: 96px;
    padding: 0.9rem;
    border: 1px solid rgba(255, 255, 255, 0.09);
    border-radius: 14px;
    background: rgba(5, 0, 15, 0.58);
}

.hia-donor-stat strong {
    display: block;
    color: var(--hia-cyan);
    font-family: "Orbitron", sans-serif;
    font-size: clamp(1.2rem, 2.4vw, 1.7rem);
    line-height: 1.1;
    margin-bottom: 0.35rem;
}

.hia-donor-stat:nth-child(2) strong { color: var(--hia-green); }
.hia-donor-stat:nth-child(3) strong { color: var(--hia-gold); }
.hia-donor-stat:nth-child(4) strong { color: var(--hia-pink); }

.hia-donor-stat span {
    display: block;
    color: var(--hia-soft);
    font-size: 0.7rem;
    line-height: 1.4;
}

.hia-dataset-strip {
    position: sticky;
    top: calc(var(--laca-nav-height, 76px) + 16px);
    z-index: 50;
    display: flex;
    flex-wrap: wrap;
    gap: 0.5rem;
    margin: 0 0 clamp(1.6rem, 3vw, 2.4rem);
    padding: 0.7rem;
    border: 1px solid rgba(255, 255, 255, 0.09);
    border-radius: 16px;
    background: rgba(10, 1, 24, 0.88);
    box-shadow: 0 12px 35px rgba(0, 0, 0, 0.18);
    backdrop-filter: blur(16px) saturate(130%);
}

.hia-dataset-pill,
.hia-dataset-toggle {
    display: inline-flex;
    align-items: center;
    min-height: 38px;
    padding: 0.5rem 0.8rem;
    border: 1px solid rgba(0, 240, 255, 0.2);
    border-radius: 999px;
    color: rgba(255, 255, 255, 0.78);
    background: rgba(0, 240, 255, 0.045);
    font-family: "Azeret Mono", monospace;
    font-size: 0.66rem;
    letter-spacing: 0.03em;
    text-decoration: none;
    transition: color 180ms ease, border-color 180ms ease, background 180ms ease;
}

.hia-dataset-pill:hover,
.hia-dataset-pill:focus-visible,
.hia-dataset-pill-active {
    color: #fff;
    border-color: rgba(0, 240, 255, 0.62);
    background: rgba(0, 240, 255, 0.14);
    outline: none;
}

.hia-dataset-pill-hidden {
    display: none;
}

.hia-dataset-toggle {
    border-style: dashed;
    color: var(--hia-cyan);
    cursor: pointer;
}

.hia-dataset-toggle:hover,
.hia-dataset-toggle:focus-visible {
    border-style: solid;
    color: #fff;
    outline: none;
}

.hia-context {
    display: grid;
    grid-template-columns: repeat(3, minmax(0, 1fr));
    gap: 0.8rem;
    margin-bottom: 1.1rem;
}

.hia-context div {
    min-height: 86px;
    padding: 1rem 1.05rem;
    border: 1px solid var(--hia-border);
    border-radius: 16px;
    background:
        linear-gradient(145deg, rgba(255, 255, 255, 0.04), transparent 45%),
        var(--hia-surface);
    box-shadow: inset 0 1px rgba(255, 255, 255, 0.045);
    backdrop-filter: blur(16px);
    color: rgba(255, 255, 255, 0.9);
}

.hia-context strong {
    display: block;
    margin-bottom: 0.35rem;
    color: var(--hia-cyan);
    font-family: "Azeret Mono", monospace;
    font-size: 0.64rem;
    letter-spacing: 0.12em;
    text-transform: uppercase;
}

.hia-alert {
    margin: 0 0 1.1rem;
    padding: 0.95rem 1.1rem;
    border: 1px solid rgba(255, 215, 0, 0.22);
    border-left: 3px solid var(--hia-gold);
    border-radius: 14px;
    background: rgba(255, 215, 0, 0.05);
    color: var(--hia-copy);
    font-size: 0.86rem;
    line-height: 1.65;
}

.hia-table-panel {
    overflow: hidden;
    border: 1px solid var(--hia-border);
    border-radius: 20px;
    background: var(--hia-surface);
    box-shadow: 0 20px 55px rgba(0, 0, 0, 0.22), inset 0 1px 0 rgba(255, 255, 255, 0.05);
}

.hia-table-head {
    display: flex;
    justify-content: space-between;
    gap: 1rem;
    align-items: end;
    padding: 1.15rem 1.2rem 1rem;
    border-bottom: 1px solid rgba(255, 255, 255, 0.08);
}

.hia-table-head h2 {
    margin: 0 0 0.35rem;
    color: #fff;
    font-family: "Orbitron", sans-serif;
    font-size: clamp(1.15rem, 2vw, 1.55rem);
    letter-spacing: -0.02em;
}

.hia-table-head p,
.hia-page-summary {
    color: var(--hia-soft);
    font-size: 0.78rem;
    line-height: 1.5;
}

.hia-search {
    display: flex;
    flex-direction: column;
    align-items: flex-end;
    gap: 0.55rem;
}

.hia-search input {
    min-width: min(360px, 72vw);
    min-height: 44px;
    padding: 0 0.95rem;
    border: 1px solid rgba(0, 240, 255, 0.26);
    border-radius: 999px;
    background: rgba(5, 0, 15, 0.42);
    color: #fff;
    font-family: "Azeret Mono", monospace;
    font-size: 0.76rem;
}

.hia-search input:focus {
    outline: none;
    border-color: var(--hia-cyan);
    box-shadow: 0 0 0 3px rgba(0, 240, 255, 0.1);
}

.hia-filter-tabs {
    display: inline-flex;
    flex-wrap: wrap;
    justify-content: flex-end;
    gap: 0.4rem;
}

.hia-filter-tabs button {
    min-height: 34px;
    padding: 0 0.75rem;
    border: 1px solid rgba(255, 255, 255, 0.14);
    border-radius: 999px;
    background: rgba(255, 255, 255, 0.05);
    color: rgba(255, 255, 255, 0.72);
    font-family: "Azeret Mono", monospace;
    font-size: 0.64rem;
    letter-spacing: 0.04em;
}

.hia-filter-tabs button[aria-pressed="true"],
.hia-filter-tabs button:hover,
.hia-filter-tabs button:focus-visible {
    border-color: rgba(0, 240, 255, 0.5);
    color: #fff;
    background: rgba(0, 240, 255, 0.12);
    outline: none;
}

.hia-table-wrap {
    overflow-x: auto;
    -webkit-overflow-scrolling: touch;
    scrollbar-width: thin;
    scrollbar-color: var(--hia-cyan) rgba(255, 255, 255, 0.08);
}

.hia-donor-table {
    width: 100%;
    min-width: 860px;
    border-collapse: separate;
    border-spacing: 0;
}

.hia-donor-table th,
.hia-donor-table td {
    padding: 0.88rem 0.95rem;
    border-bottom: 1px solid rgba(255, 255, 255, 0.075);
    vertical-align: top;
    text-align: left;
}

.hia-donor-table th {
    position: sticky;
    top: 0;
    z-index: 1;
    color: var(--hia-cyan);
    background: var(--hia-surface-strong);
    font-family: "Azeret Mono", monospace;
    font-size: 0.66rem;
    font-weight: 700;
    letter-spacing: 0.08em;
    text-transform: uppercase;
}

.hia-donor-table td {
    color: rgba(255, 255, 255, 0.86);
    font-size: 0.86rem;
    line-height: 1.55;
    overflow-wrap: anywhere;
}

.hia-donor-table tbody tr:nth-child(even) td {
    background: rgba(255, 255, 255, 0.026);
}

.hia-donor-table tbody tr:hover td {
    background: rgba(0, 240, 255, 0.055);
}

.hia-donor-table td:nth-child(1) { max-width: 240px; }
.hia-donor-table td:nth-child(5) { max-width: 340px; }
.hia-donor-table td:nth-child(6) { max-width: 320px; }
.hia-donor-table td:last-child {
    width: 1%;
    white-space: nowrap;
    text-align: right;
}

.hia-sort-button {
    display: inline-flex;
    align-items: center;
    gap: 0.42rem;
    width: 100%;
    border: 0;
    padding: 0;
    background: transparent;
    color: inherit;
    font: inherit;
    letter-spacing: inherit;
    text-transform: inherit;
    text-align: left;
}

.hia-sort-button::after {
    content: "";
    width: 0;
    height: 0;
    border-left: 4px solid transparent;
    border-right: 4px solid transparent;
    border-top: 5px solid rgba(255, 255, 255, 0.42);
    opacity: 0.7;
}

.hia-sort-button:focus-visible {
    outline: 2px solid rgba(0, 240, 255, 0.5);
    outline-offset: 4px;
    border-radius: 4px;
}

.hia-donor-table th[data-sort-direction="asc"] .hia-sort-button::after {
    border-top: 0;
    border-bottom: 5px solid var(--hia-green);
    opacity: 1;
}

.hia-donor-table th[data-sort-direction="desc"] .hia-sort-button::after {
    border-top: 5px solid var(--hia-green);
    opacity: 1;
}

.hia-row-actions {
    display: inline-flex;
    align-items: center;
    justify-content: flex-end;
    gap: 0.45rem;
}

.hia-detail-btn,
.hia-button {
    display: inline-flex;
    align-items: center;
    justify-content: center;
    min-height: 32px;
    padding: 0.32rem 0.78rem;
    border: 1px solid rgba(0, 240, 255, 0.4);
    border-radius: 999px;
    background: rgba(0, 240, 255, 0.08);
    color: var(--hia-cyan);
    font-family: "Azeret Mono", monospace;
    font-size: 0.64rem;
    font-weight: 700;
    letter-spacing: 0.04em;
    text-decoration: none;
    transition: background 160ms ease, color 160ms ease, border-color 160ms ease;
}

.hia-detail-btn:hover,
.hia-detail-btn:focus-visible,
.hia-button:hover,
.hia-button:focus-visible {
    background: var(--hia-cyan);
    color: #04121c;
    outline: none;
}

.hia-tag,
.hia-tag-success,
.hia-tag-accent,
.hia-tag-warning {
    display: inline-flex;
    align-items: center;
    min-height: 24px;
    padding: 0.2rem 0.58rem;
    border: 1px solid rgba(255, 255, 255, 0.14);
    border-radius: 999px;
    background: rgba(255, 255, 255, 0.07);
    color: rgba(255, 255, 255, 0.84);
    font-family: "Azeret Mono", monospace;
    font-size: 0.66rem;
    font-weight: 700;
    white-space: nowrap;
}

.hia-tag-success {
    border-color: rgba(0, 255, 136, 0.34);
    color: var(--hia-green);
    background: rgba(0, 255, 136, 0.075);
}

.hia-tag-accent {
    border-color: rgba(0, 240, 255, 0.34);
    color: var(--hia-cyan);
    background: rgba(0, 240, 255, 0.075);
}

.hia-tag-warning {
    border-color: rgba(255, 215, 0, 0.34);
    color: var(--hia-gold);
    background: rgba(255, 215, 0, 0.075);
}

.hia-pager {
    display: flex;
    flex-wrap: wrap;
    justify-content: space-between;
    align-items: center;
    gap: 0.8rem;
    padding: 1rem 1.15rem;
}

.hia-pager-buttons {
    display: flex;
    gap: 0.5rem;
}

.hia-page-indicator {
    color: var(--hia-cyan);
    font-family: "Orbitron", sans-serif;
    font-size: 0.74rem;
    letter-spacing: 0.04em;
}

.hia-pager button {
    min-height: 38px;
    padding: 0.45rem 0.95rem;
    border: 1px solid rgba(0, 240, 255, 0.28);
    border-radius: 999px;
    background: rgba(0, 240, 255, 0.08);
    color: #fff;
    font-family: "Azeret Mono", monospace;
    font-size: 0.68rem;
}

.hia-pager button:hover:not(:disabled),
.hia-pager button:focus-visible:not(:disabled) {
    border-color: var(--hia-cyan);
    outline: none;
}

.hia-pager button:disabled {
    cursor: not-allowed;
    opacity: 0.42;
}

.hia-modal-overlay {
    position: fixed;
    inset: 0;
    z-index: 3000;
    display: none;
    align-items: center;
    justify-content: center;
    padding: 1.5rem;
    background:
        radial-gradient(120% 120% at 50% 0%, rgba(0, 240, 255, 0.08), transparent 55%),
        rgba(2, 4, 8, 0.74);
    backdrop-filter: blur(8px);
}

.hia-modal-overlay.open {
    display: flex;
}

.hia-modal {
    width: min(740px, 100%);
    max-height: 86vh;
    display: flex;
    flex-direction: column;
    overflow: hidden;
    border: 1px solid var(--hia-border);
    border-radius: 22px;
    background:
        linear-gradient(145deg, rgba(255, 255, 255, 0.05), transparent 38%),
        var(--hia-surface-strong);
    box-shadow: 0 30px 80px rgba(0, 0, 0, 0.5);
}

.hia-modal-head {
    display: flex;
    align-items: center;
    justify-content: space-between;
    gap: 1rem;
    padding: 1.15rem 1.3rem 1rem;
    border-bottom: 1px solid rgba(255, 255, 255, 0.08);
}

.hia-modal-kicker {
    display: inline-flex;
    align-items: center;
    gap: 0.45rem;
    margin-bottom: 0.35rem;
    color: var(--hia-green);
    font-family: "Azeret Mono", monospace;
    font-size: 0.62rem;
    letter-spacing: 0.14em;
    text-transform: uppercase;
}

.hia-modal-head h3 {
    margin: 0;
    color: #fff;
    font-family: "Orbitron", sans-serif;
    font-size: 1.05rem;
    word-break: break-word;
}

.hia-modal-close {
    flex: 0 0 auto;
    width: 36px;
    height: 36px;
    border: 1px solid rgba(255, 255, 255, 0.18);
    border-radius: 999px;
    background: rgba(255, 255, 255, 0.04);
    color: rgba(255, 255, 255, 0.72);
}

.hia-modal-close:hover,
.hia-modal-close:focus-visible {
    border-color: var(--hia-cyan);
    color: #04121c;
    background: var(--hia-cyan);
    outline: none;
}

.hia-modal-body {
    padding: 1.15rem 1.3rem 1.4rem;
    overflow-y: auto;
    scrollbar-width: thin;
}

.hia-modal-grid {
    display: grid;
    grid-template-columns: repeat(2, minmax(0, 1fr));
    gap: 0.7rem;
}

.hia-modal-field {
    min-width: 0;
    padding: 0.65rem 0.8rem;
    border: 1px solid rgba(255, 255, 255, 0.08);
    border-radius: 12px;
    background: rgba(255, 255, 255, 0.03);
}

.hia-modal-field.full {
    grid-column: 1 / -1;
}

.hia-modal-field dt {
    margin-bottom: 0.3rem;
    color: var(--hia-cyan);
    font-family: "Azeret Mono", monospace;
    font-size: 0.6rem;
    letter-spacing: 0.12em;
    text-transform: uppercase;
}

.hia-modal-field dd {
    margin: 0;
    color: rgba(255, 255, 255, 0.92);
    font-size: 0.9rem;
    line-height: 1.55;
    word-break: break-word;
}

.hia-modal-field dd a {
    color: var(--hia-cyan);
    text-decoration: none;
}

.hia-modal-actions {
    display: flex;
    flex-wrap: wrap;
    gap: 0.7rem;
    margin-top: 1.1rem;
    padding-top: 1.05rem;
    border-top: 1px solid rgba(255, 255, 255, 0.08);
}

.hia-modal-actions #hiaDonorModalDetailLink {
    background: linear-gradient(90deg, var(--hia-cyan), rgba(0, 240, 255, 0.75));
    border-color: transparent;
    color: #04121c;
}

.hia-modal-actions #hiaDonorModalDone {
    background: transparent;
    border-color: rgba(255, 255, 255, 0.22);
    color: rgba(255, 255, 255, 0.78);
}

@media (max-width: 980px) {
    .hia-donor-top,
    .hia-context {
        grid-template-columns: 1fr;
    }

    .hia-donor-top {
        padding-top: clamp(6.4rem, 16vw, 8.2rem);
    }

    .hia-table-head,
    .hia-search {
        display: block;
    }

    .hia-search {
        margin-top: 0.85rem;
    }

    .hia-search input,
    .hia-filter-tabs {
        width: 100%;
        justify-content: flex-start;
    }

    .hia-dataset-strip {
        flex-wrap: nowrap;
        overflow-x: auto;
        scrollbar-width: thin;
    }
}

@media (max-width: 620px) {
    .hia-donor-shell {
        width: min(var(--hia-width), calc(100% - 1.4rem));
    }

    .hia-donor-stats,
    .hia-modal-grid {
        grid-template-columns: 1fr;
    }

    .hia-donor-table {
        min-width: 720px;
    }
}

@media (prefers-reduced-motion: reduce) {
    .hia-donor-pill,
    .hia-dataset-pill,
    .hia-detail-btn {
        transition: none;
    }

    .hia-donor-pill:hover {
        transform: none;
    }
}