{
  "generated_at": "2026-07-09 12:54:49 +0800",
  "dataset_id": "ds-cancerscem-2",
  "dataset_name": "CancerSCEM 2.0",
  "sample_id": "ESCC-111-07-1A",
  "donor_id": "ESCC-111-07-1A",
  "summary": {
    "sample_id": "ESCC-111-07-1A",
    "donor_id": "ESCC-111-07-1A",
    "cancer_type": "ESCC",
    "health_status": "Esophageal Squamous Cell Carcinoma; Tumour",
    "tissue_or_cell_source": "Tumour",
    "cells_in_umap_file": 4480,
    "cells_analyzed": 1998,
    "clusters": 22,
    "genes_read": 23818,
    "genes_nonzero_in_analyzed_cells": 22940,
    "mean_umi": 7679,
    "mean_genes": 1979,
    "mean_pct_mito": 2.999,
    "matrix_status": "Matrix available",
    "detail_url": "human-immune-donor-detail.php?dataset_id=ds-cancerscem-2&donor_id=ESCC-111-07-1A",
    "umap_href": "IMG/umap/cancerscem-2/donor/ESCC-111-07-1A.png",
    "umap_coordinates_url": "http://8.142.154.29/LACA/data/human_immune_atlas/cancerscem_2_umap/ESCC-111-07-1A.umap.tsv.gz",
    "umap_summary_url": "http://8.142.154.29/LACA/data/human_immune_atlas/cancerscem_2_umap/ESCC-111-07-1A.summary.json"
  },
  "visualizations": [
    {
      "title": "Donor-level analysis panel",
      "href": "IMG/human-immune-analysis/cancerscem-deep/donor/ESCC-111-07-1A.analysis.png",
      "description": "Cluster cell counts, cluster-by-program score heatmap, and top marker genes."
    }
  ],
  "cluster_qc": [
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_1",
      "cells": 207,
      "mean_umi": 4334.2754,
      "median_genes": 1541,
      "mean_pct_mito": 3.0996
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_2",
      "cells": 198,
      "mean_umi": 3997.2071,
      "median_genes": 1605.5,
      "mean_pct_mito": 2.6175
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_3",
      "cells": 186,
      "mean_umi": 5137.6183,
      "median_genes": 1998,
      "mean_pct_mito": 3.1346
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_4",
      "cells": 183,
      "mean_umi": 4824.4317,
      "median_genes": 1796,
      "mean_pct_mito": 2.7968
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_5",
      "cells": 162,
      "mean_umi": 11806.6914,
      "median_genes": 4178,
      "mean_pct_mito": 4.7288
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_6",
      "cells": 145,
      "mean_umi": 4497.3241,
      "median_genes": 1515,
      "mean_pct_mito": 4.2773
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_7",
      "cells": 140,
      "mean_umi": 4763.6786,
      "median_genes": 1748,
      "mean_pct_mito": 3.4427
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_8",
      "cells": 133,
      "mean_umi": 22725.3459,
      "median_genes": 2004,
      "mean_pct_mito": 1.2356
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_9",
      "cells": 128,
      "mean_umi": 6318.4922,
      "median_genes": 1533,
      "mean_pct_mito": 2.9181
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_10",
      "cells": 105,
      "mean_umi": 8455.2952,
      "median_genes": 1876,
      "mean_pct_mito": 1.389
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_11",
      "cells": 91,
      "mean_umi": 10361.4176,
      "median_genes": 3034,
      "mean_pct_mito": 3.5257
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_12",
      "cells": 88,
      "mean_umi": 1112.3068,
      "median_genes": 350,
      "mean_pct_mito": 0.9475
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_13",
      "cells": 47,
      "mean_umi": 3805.1064,
      "median_genes": 1824,
      "mean_pct_mito": 6.8133
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_14",
      "cells": 38,
      "mean_umi": 10408.3684,
      "median_genes": 3072,
      "mean_pct_mito": 3.3801
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_15",
      "cells": 36,
      "mean_umi": 7463.3889,
      "median_genes": 2666.5,
      "mean_pct_mito": 4.0197
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_16",
      "cells": 30,
      "mean_umi": 30266.6333,
      "median_genes": 2140,
      "mean_pct_mito": 0.7202
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_17",
      "cells": 21,
      "mean_umi": 4510,
      "median_genes": 1638,
      "mean_pct_mito": 3.3266
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_18",
      "cells": 17,
      "mean_umi": 4749.0588,
      "median_genes": 2203,
      "mean_pct_mito": 2.8857
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_19",
      "cells": 14,
      "mean_umi": 22625.5,
      "median_genes": 2114.5,
      "mean_pct_mito": 1.2295
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_20",
      "cells": 13,
      "mean_umi": 20450.0769,
      "median_genes": 2532,
      "mean_pct_mito": 1.0993
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_21",
      "cells": 12,
      "mean_umi": 22329.6667,
      "median_genes": 2194,
      "mean_pct_mito": 0.696
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_22",
      "cells": 4,
      "mean_umi": 11630.5,
      "median_genes": 2168.5,
      "mean_pct_mito": 1.8092
    }
  ],
  "program_scores": [
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_22",
      "program": "B_plasma",
      "genes_used": 8,
      "mean_log1p_score": 3.2133
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_21",
      "program": "B_plasma",
      "genes_used": 8,
      "mean_log1p_score": 2.683
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_20",
      "program": "B_plasma",
      "genes_used": 8,
      "mean_log1p_score": 2.6752
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_8",
      "program": "B_plasma",
      "genes_used": 8,
      "mean_log1p_score": 2.5166
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_16",
      "program": "B_plasma",
      "genes_used": 8,
      "mean_log1p_score": 2.1089
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_19",
      "program": "B_plasma",
      "genes_used": 8,
      "mean_log1p_score": 1.9731
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_14",
      "program": "B_plasma",
      "genes_used": 8,
      "mean_log1p_score": 1.3862
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_6",
      "program": "B_plasma",
      "genes_used": 8,
      "mean_log1p_score": 1.0846
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_9",
      "program": "B_plasma",
      "genes_used": 8,
      "mean_log1p_score": 0.4232
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_18",
      "program": "B_plasma",
      "genes_used": 8,
      "mean_log1p_score": 0.4161
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_3",
      "program": "B_plasma",
      "genes_used": 8,
      "mean_log1p_score": 0.3724
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_2",
      "program": "B_plasma",
      "genes_used": 8,
      "mean_log1p_score": 0.2879
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_4",
      "program": "B_plasma",
      "genes_used": 8,
      "mean_log1p_score": 0.2473
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_7",
      "program": "B_plasma",
      "genes_used": 8,
      "mean_log1p_score": 0.2277
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_1",
      "program": "B_plasma",
      "genes_used": 8,
      "mean_log1p_score": 0.2124
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_17",
      "program": "B_plasma",
      "genes_used": 8,
      "mean_log1p_score": 0.1896
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_13",
      "program": "B_plasma",
      "genes_used": 8,
      "mean_log1p_score": 0.1384
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_15",
      "program": "B_plasma",
      "genes_used": 8,
      "mean_log1p_score": 0.0755
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_11",
      "program": "B_plasma",
      "genes_used": 8,
      "mean_log1p_score": 0.0742
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_12",
      "program": "B_plasma",
      "genes_used": 8,
      "mean_log1p_score": 0.0308
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_10",
      "program": "B_plasma",
      "genes_used": 8,
      "mean_log1p_score": 0.0171
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_5",
      "program": "B_plasma",
      "genes_used": 8,
      "mean_log1p_score": 0.0137
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_3",
      "program": "Checkpoint_exhaustion",
      "genes_used": 8,
      "mean_log1p_score": 0.4071
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_14",
      "program": "Checkpoint_exhaustion",
      "genes_used": 8,
      "mean_log1p_score": 0.3213
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_4",
      "program": "Checkpoint_exhaustion",
      "genes_used": 8,
      "mean_log1p_score": 0.2824
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_2",
      "program": "Checkpoint_exhaustion",
      "genes_used": 8,
      "mean_log1p_score": 0.2145
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_7",
      "program": "Checkpoint_exhaustion",
      "genes_used": 8,
      "mean_log1p_score": 0.1973
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_1",
      "program": "Checkpoint_exhaustion",
      "genes_used": 8,
      "mean_log1p_score": 0.135
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_20",
      "program": "Checkpoint_exhaustion",
      "genes_used": 8,
      "mean_log1p_score": 0.0956
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_21",
      "program": "Checkpoint_exhaustion",
      "genes_used": 8,
      "mean_log1p_score": 0.0921
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_16",
      "program": "Checkpoint_exhaustion",
      "genes_used": 8,
      "mean_log1p_score": 0.0897
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_9",
      "program": "Checkpoint_exhaustion",
      "genes_used": 8,
      "mean_log1p_score": 0.0831
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_13",
      "program": "Checkpoint_exhaustion",
      "genes_used": 8,
      "mean_log1p_score": 0.0798
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_11",
      "program": "Checkpoint_exhaustion",
      "genes_used": 8,
      "mean_log1p_score": 0.0731
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_15",
      "program": "Checkpoint_exhaustion",
      "genes_used": 8,
      "mean_log1p_score": 0.0713
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_5",
      "program": "Checkpoint_exhaustion",
      "genes_used": 8,
      "mean_log1p_score": 0.0689
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_8",
      "program": "Checkpoint_exhaustion",
      "genes_used": 8,
      "mean_log1p_score": 0.0687
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_22",
      "program": "Checkpoint_exhaustion",
      "genes_used": 8,
      "mean_log1p_score": 0.065
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_17",
      "program": "Checkpoint_exhaustion",
      "genes_used": 8,
      "mean_log1p_score": 0.0568
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_6",
      "program": "Checkpoint_exhaustion",
      "genes_used": 8,
      "mean_log1p_score": 0.0355
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_19",
      "program": "Checkpoint_exhaustion",
      "genes_used": 8,
      "mean_log1p_score": 0.032
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_12",
      "program": "Checkpoint_exhaustion",
      "genes_used": 8,
      "mean_log1p_score": 0.0202
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_18",
      "program": "Checkpoint_exhaustion",
      "genes_used": 8,
      "mean_log1p_score": 0.0183
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_10",
      "program": "Checkpoint_exhaustion",
      "genes_used": 8,
      "mean_log1p_score": 0.0127
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_13",
      "program": "Endothelial",
      "genes_used": 7,
      "mean_log1p_score": 1.1217
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_21",
      "program": "Endothelial",
      "genes_used": 7,
      "mean_log1p_score": 0.1527
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_22",
      "program": "Endothelial",
      "genes_used": 7,
      "mean_log1p_score": 0.1462
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_15",
      "program": "Endothelial",
      "genes_used": 7,
      "mean_log1p_score": 0.146
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_16",
      "program": "Endothelial",
      "genes_used": 7,
      "mean_log1p_score": 0.1313
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_19",
      "program": "Endothelial",
      "genes_used": 7,
      "mean_log1p_score": 0.1312
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_20",
      "program": "Endothelial",
      "genes_used": 7,
      "mean_log1p_score": 0.1303
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_8",
      "program": "Endothelial",
      "genes_used": 7,
      "mean_log1p_score": 0.1022
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_11",
      "program": "Endothelial",
      "genes_used": 7,
      "mean_log1p_score": 0.0737
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_9",
      "program": "Endothelial",
      "genes_used": 7,
      "mean_log1p_score": 0.0605
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_7",
      "program": "Endothelial",
      "genes_used": 7,
      "mean_log1p_score": 0.0322
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_2",
      "program": "Endothelial",
      "genes_used": 7,
      "mean_log1p_score": 0.0152
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_10",
      "program": "Endothelial",
      "genes_used": 7,
      "mean_log1p_score": 0.0145
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_18",
      "program": "Endothelial",
      "genes_used": 7,
      "mean_log1p_score": 0.0116
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_5",
      "program": "Endothelial",
      "genes_used": 7,
      "mean_log1p_score": 0.0111
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_6",
      "program": "Endothelial",
      "genes_used": 7,
      "mean_log1p_score": 0.0079
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_12",
      "program": "Endothelial",
      "genes_used": 7,
      "mean_log1p_score": 0.0068
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_1",
      "program": "Endothelial",
      "genes_used": 7,
      "mean_log1p_score": 0.0029
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_14",
      "program": "Endothelial",
      "genes_used": 7,
      "mean_log1p_score": 0.0026
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_4",
      "program": "Endothelial",
      "genes_used": 7,
      "mean_log1p_score": 0.0022
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_3",
      "program": "Endothelial",
      "genes_used": 7,
      "mean_log1p_score": 0.0016
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_17",
      "program": "Endothelial",
      "genes_used": 7,
      "mean_log1p_score": 0
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_5",
      "program": "Epithelial_tumor",
      "genes_used": 8,
      "mean_log1p_score": 1.68
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_10",
      "program": "Epithelial_tumor",
      "genes_used": 8,
      "mean_log1p_score": 1.1948
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_18",
      "program": "Epithelial_tumor",
      "genes_used": 8,
      "mean_log1p_score": 0.0942
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_15",
      "program": "Epithelial_tumor",
      "genes_used": 8,
      "mean_log1p_score": 0.0623
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_11",
      "program": "Epithelial_tumor",
      "genes_used": 8,
      "mean_log1p_score": 0.0308
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_13",
      "program": "Epithelial_tumor",
      "genes_used": 8,
      "mean_log1p_score": 0.0214
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_17",
      "program": "Epithelial_tumor",
      "genes_used": 8,
      "mean_log1p_score": 0.0189
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_19",
      "program": "Epithelial_tumor",
      "genes_used": 8,
      "mean_log1p_score": 0.0186
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_8",
      "program": "Epithelial_tumor",
      "genes_used": 8,
      "mean_log1p_score": 0.0112
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_9",
      "program": "Epithelial_tumor",
      "genes_used": 8,
      "mean_log1p_score": 0.0107
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_21",
      "program": "Epithelial_tumor",
      "genes_used": 8,
      "mean_log1p_score": 0.0072
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_7",
      "program": "Epithelial_tumor",
      "genes_used": 8,
      "mean_log1p_score": 0.0066
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_12",
      "program": "Epithelial_tumor",
      "genes_used": 8,
      "mean_log1p_score": 0.0059
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_16",
      "program": "Epithelial_tumor",
      "genes_used": 8,
      "mean_log1p_score": 0.0058
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_6",
      "program": "Epithelial_tumor",
      "genes_used": 8,
      "mean_log1p_score": 0.0048
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_3",
      "program": "Epithelial_tumor",
      "genes_used": 8,
      "mean_log1p_score": 0.0035
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_4",
      "program": "Epithelial_tumor",
      "genes_used": 8,
      "mean_log1p_score": 0.0026
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_14",
      "program": "Epithelial_tumor",
      "genes_used": 8,
      "mean_log1p_score": 0.0023
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_2",
      "program": "Epithelial_tumor",
      "genes_used": 8,
      "mean_log1p_score": 0.0009
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_1",
      "program": "Epithelial_tumor",
      "genes_used": 8,
      "mean_log1p_score": 0.0004
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_20",
      "program": "Epithelial_tumor",
      "genes_used": 8,
      "mean_log1p_score": 0
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_22",
      "program": "Epithelial_tumor",
      "genes_used": 8,
      "mean_log1p_score": 0
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_11",
      "program": "Fibroblast_stroma",
      "genes_used": 8,
      "mean_log1p_score": 2.1763
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_15",
      "program": "Fibroblast_stroma",
      "genes_used": 8,
      "mean_log1p_score": 1.3198
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_18",
      "program": "Fibroblast_stroma",
      "genes_used": 8,
      "mean_log1p_score": 0.1622
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_5",
      "program": "Fibroblast_stroma",
      "genes_used": 8,
      "mean_log1p_score": 0.0571
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_10",
      "program": "Fibroblast_stroma",
      "genes_used": 8,
      "mean_log1p_score": 0.0255
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_16",
      "program": "Fibroblast_stroma",
      "genes_used": 8,
      "mean_log1p_score": 0.0132
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_14",
      "program": "Fibroblast_stroma",
      "genes_used": 8,
      "mean_log1p_score": 0.0127
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_13",
      "program": "Fibroblast_stroma",
      "genes_used": 8,
      "mean_log1p_score": 0.0111
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_3",
      "program": "Fibroblast_stroma",
      "genes_used": 8,
      "mean_log1p_score": 0.0105
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_21",
      "program": "Fibroblast_stroma",
      "genes_used": 8,
      "mean_log1p_score": 0.0072
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_9",
      "program": "Fibroblast_stroma",
      "genes_used": 8,
      "mean_log1p_score": 0.0065
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_19",
      "program": "Fibroblast_stroma",
      "genes_used": 8,
      "mean_log1p_score": 0.0062
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_4",
      "program": "Fibroblast_stroma",
      "genes_used": 8,
      "mean_log1p_score": 0.0062
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_8",
      "program": "Fibroblast_stroma",
      "genes_used": 8,
      "mean_log1p_score": 0.0052
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_17",
      "program": "Fibroblast_stroma",
      "genes_used": 8,
      "mean_log1p_score": 0.0041
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_2",
      "program": "Fibroblast_stroma",
      "genes_used": 8,
      "mean_log1p_score": 0.0039
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_1",
      "program": "Fibroblast_stroma",
      "genes_used": 8,
      "mean_log1p_score": 0.0038
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_6",
      "program": "Fibroblast_stroma",
      "genes_used": 8,
      "mean_log1p_score": 0.0036
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_7",
      "program": "Fibroblast_stroma",
      "genes_used": 8,
      "mean_log1p_score": 0.0025
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_12",
      "program": "Fibroblast_stroma",
      "genes_used": 8,
      "mean_log1p_score": 0.002
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_20",
      "program": "Fibroblast_stroma",
      "genes_used": 8,
      "mean_log1p_score": 0
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_22",
      "program": "Fibroblast_stroma",
      "genes_used": 8,
      "mean_log1p_score": 0
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_9",
      "program": "Myeloid_APC",
      "genes_used": 9,
      "mean_log1p_score": 1.0388
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_6",
      "program": "Myeloid_APC",
      "genes_used": 9,
      "mean_log1p_score": 0.41
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_12",
      "program": "Myeloid_APC",
      "genes_used": 9,
      "mean_log1p_score": 0.397
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_14",
      "program": "Myeloid_APC",
      "genes_used": 9,
      "mean_log1p_score": 0.3445
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_10",
      "program": "Myeloid_APC",
      "genes_used": 9,
      "mean_log1p_score": 0.2091
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_18",
      "program": "Myeloid_APC",
      "genes_used": 9,
      "mean_log1p_score": 0.1881
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_2",
      "program": "Myeloid_APC",
      "genes_used": 9,
      "mean_log1p_score": 0.1147
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_7",
      "program": "Myeloid_APC",
      "genes_used": 9,
      "mean_log1p_score": 0.0825
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_22",
      "program": "Myeloid_APC",
      "genes_used": 9,
      "mean_log1p_score": 0.069
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_17",
      "program": "Myeloid_APC",
      "genes_used": 9,
      "mean_log1p_score": 0.0682
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_3",
      "program": "Myeloid_APC",
      "genes_used": 9,
      "mean_log1p_score": 0.0547
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_4",
      "program": "Myeloid_APC",
      "genes_used": 9,
      "mean_log1p_score": 0.0479
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_20",
      "program": "Myeloid_APC",
      "genes_used": 9,
      "mean_log1p_score": 0.0471
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_15",
      "program": "Myeloid_APC",
      "genes_used": 9,
      "mean_log1p_score": 0.0424
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_13",
      "program": "Myeloid_APC",
      "genes_used": 9,
      "mean_log1p_score": 0.0318
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_1",
      "program": "Myeloid_APC",
      "genes_used": 9,
      "mean_log1p_score": 0.0306
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_16",
      "program": "Myeloid_APC",
      "genes_used": 9,
      "mean_log1p_score": 0.0199
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_5",
      "program": "Myeloid_APC",
      "genes_used": 9,
      "mean_log1p_score": 0.018
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_8",
      "program": "Myeloid_APC",
      "genes_used": 9,
      "mean_log1p_score": 0.0111
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_19",
      "program": "Myeloid_APC",
      "genes_used": 9,
      "mean_log1p_score": 0.011
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_21",
      "program": "Myeloid_APC",
      "genes_used": 9,
      "mean_log1p_score": 0.0102
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_11",
      "program": "Myeloid_APC",
      "genes_used": 9,
      "mean_log1p_score": 0.0042
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_14",
      "program": "Proliferation",
      "genes_used": 7,
      "mean_log1p_score": 0.8088
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_5",
      "program": "Proliferation",
      "genes_used": 7,
      "mean_log1p_score": 0.3755
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_10",
      "program": "Proliferation",
      "genes_used": 7,
      "mean_log1p_score": 0.3311
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_11",
      "program": "Proliferation",
      "genes_used": 7,
      "mean_log1p_score": 0.0829
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_18",
      "program": "Proliferation",
      "genes_used": 7,
      "mean_log1p_score": 0.0709
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_17",
      "program": "Proliferation",
      "genes_used": 7,
      "mean_log1p_score": 0.0649
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_15",
      "program": "Proliferation",
      "genes_used": 7,
      "mean_log1p_score": 0.061
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_7",
      "program": "Proliferation",
      "genes_used": 7,
      "mean_log1p_score": 0.0602
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_2",
      "program": "Proliferation",
      "genes_used": 7,
      "mean_log1p_score": 0.0563
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_13",
      "program": "Proliferation",
      "genes_used": 7,
      "mean_log1p_score": 0.0475
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_3",
      "program": "Proliferation",
      "genes_used": 7,
      "mean_log1p_score": 0.0429
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_9",
      "program": "Proliferation",
      "genes_used": 7,
      "mean_log1p_score": 0.0407
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_6",
      "program": "Proliferation",
      "genes_used": 7,
      "mean_log1p_score": 0.038
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_1",
      "program": "Proliferation",
      "genes_used": 7,
      "mean_log1p_score": 0.0367
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_21",
      "program": "Proliferation",
      "genes_used": 7,
      "mean_log1p_score": 0.033
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_4",
      "program": "Proliferation",
      "genes_used": 7,
      "mean_log1p_score": 0.0291
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_16",
      "program": "Proliferation",
      "genes_used": 7,
      "mean_log1p_score": 0.0283
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_20",
      "program": "Proliferation",
      "genes_used": 7,
      "mean_log1p_score": 0.0273
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_8",
      "program": "Proliferation",
      "genes_used": 7,
      "mean_log1p_score": 0.0194
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_19",
      "program": "Proliferation",
      "genes_used": 7,
      "mean_log1p_score": 0.0141
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_12",
      "program": "Proliferation",
      "genes_used": 7,
      "mean_log1p_score": 0.0011
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_22",
      "program": "Proliferation",
      "genes_used": 7,
      "mean_log1p_score": 0
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_7",
      "program": "T_NK_cytotoxic",
      "genes_used": 10,
      "mean_log1p_score": 1.2177
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_2",
      "program": "T_NK_cytotoxic",
      "genes_used": 10,
      "mean_log1p_score": 1.001
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_4",
      "program": "T_NK_cytotoxic",
      "genes_used": 10,
      "mean_log1p_score": 0.8121
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_3",
      "program": "T_NK_cytotoxic",
      "genes_used": 10,
      "mean_log1p_score": 0.5704
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_1",
      "program": "T_NK_cytotoxic",
      "genes_used": 10,
      "mean_log1p_score": 0.4769
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_14",
      "program": "T_NK_cytotoxic",
      "genes_used": 10,
      "mean_log1p_score": 0.4491
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_16",
      "program": "T_NK_cytotoxic",
      "genes_used": 10,
      "mean_log1p_score": 0.0953
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_21",
      "program": "T_NK_cytotoxic",
      "genes_used": 10,
      "mean_log1p_score": 0.0679
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_8",
      "program": "T_NK_cytotoxic",
      "genes_used": 10,
      "mean_log1p_score": 0.0552
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_11",
      "program": "T_NK_cytotoxic",
      "genes_used": 10,
      "mean_log1p_score": 0.0537
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_17",
      "program": "T_NK_cytotoxic",
      "genes_used": 10,
      "mean_log1p_score": 0.0376
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_12",
      "program": "T_NK_cytotoxic",
      "genes_used": 10,
      "mean_log1p_score": 0.0322
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_9",
      "program": "T_NK_cytotoxic",
      "genes_used": 10,
      "mean_log1p_score": 0.0318
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_6",
      "program": "T_NK_cytotoxic",
      "genes_used": 10,
      "mean_log1p_score": 0.0315
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_10",
      "program": "T_NK_cytotoxic",
      "genes_used": 10,
      "mean_log1p_score": 0.0181
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_19",
      "program": "T_NK_cytotoxic",
      "genes_used": 10,
      "mean_log1p_score": 0.0177
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_22",
      "program": "T_NK_cytotoxic",
      "genes_used": 10,
      "mean_log1p_score": 0.0173
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_5",
      "program": "T_NK_cytotoxic",
      "genes_used": 10,
      "mean_log1p_score": 0.0098
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_20",
      "program": "T_NK_cytotoxic",
      "genes_used": 10,
      "mean_log1p_score": 0.0053
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_15",
      "program": "T_NK_cytotoxic",
      "genes_used": 10,
      "mean_log1p_score": 0.0019
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_13",
      "program": "T_NK_cytotoxic",
      "genes_used": 10,
      "mean_log1p_score": 0.0015
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_18",
      "program": "T_NK_cytotoxic",
      "genes_used": 10,
      "mean_log1p_score": 0
    }
  ],
  "program_summary": [
    {
      "program": "B_plasma",
      "cluster_count": 22,
      "mean_score": 0.9258,
      "max_score": 3.2133,
      "mean_genes_used": 8
    },
    {
      "program": "T_NK_cytotoxic",
      "cluster_count": 22,
      "mean_score": 0.2275,
      "max_score": 1.2177,
      "mean_genes_used": 10
    },
    {
      "program": "Fibroblast_stroma",
      "cluster_count": 22,
      "mean_score": 0.1745,
      "max_score": 2.1763,
      "mean_genes_used": 8
    },
    {
      "program": "Myeloid_APC",
      "cluster_count": 22,
      "mean_score": 0.1478,
      "max_score": 1.0388,
      "mean_genes_used": 9
    },
    {
      "program": "Epithelial_tumor",
      "cluster_count": 22,
      "mean_score": 0.1447,
      "max_score": 1.68,
      "mean_genes_used": 8
    },
    {
      "program": "Checkpoint_exhaustion",
      "cluster_count": 22,
      "mean_score": 0.1146,
      "max_score": 0.4071,
      "mean_genes_used": 8
    },
    {
      "program": "Endothelial",
      "cluster_count": 22,
      "mean_score": 0.1047,
      "max_score": 1.1217,
      "mean_genes_used": 7
    },
    {
      "program": "Proliferation",
      "cluster_count": 22,
      "mean_score": 0.1032,
      "max_score": 0.8088,
      "mean_genes_used": 7
    }
  ],
  "top_markers": [
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_21",
      "rank": 1,
      "gene": "IGKV3-15",
      "score_log1p_diff": 8.8765,
      "mean_log1p_expr": 9.2364,
      "detect_fraction": 1
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_20",
      "rank": 1,
      "gene": "IGLV1-44",
      "score_log1p_diff": 8.8183,
      "mean_log1p_expr": 8.8948,
      "detect_fraction": 1
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_22",
      "rank": 1,
      "gene": "IGHV1-69",
      "score_log1p_diff": 7.9199,
      "mean_log1p_expr": 7.9556,
      "detect_fraction": 1
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_19",
      "rank": 1,
      "gene": "IGLV1-47",
      "score_log1p_diff": 7.6608,
      "mean_log1p_expr": 7.7726,
      "detect_fraction": 1
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_16",
      "rank": 1,
      "gene": "IGLC2",
      "score_log1p_diff": 4.8171,
      "mean_log1p_expr": 4.922,
      "detect_fraction": 0.9667
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_8",
      "rank": 1,
      "gene": "IGHG1",
      "score_log1p_diff": 4.7264,
      "mean_log1p_expr": 5.01,
      "detect_fraction": 0.9398
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_11",
      "rank": 1,
      "gene": "COL1A1",
      "score_log1p_diff": 3.4854,
      "mean_log1p_expr": 3.551,
      "detect_fraction": 0.9231
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_10",
      "rank": 1,
      "gene": "KRT17",
      "score_log1p_diff": 3.439,
      "mean_log1p_expr": 3.7344,
      "detect_fraction": 0.9524
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_17",
      "rank": 1,
      "gene": "TPSAB1",
      "score_log1p_diff": 3.4354,
      "mean_log1p_expr": 3.4354,
      "detect_fraction": 1
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_15",
      "rank": 1,
      "gene": "IGFBP7",
      "score_log1p_diff": 3.341,
      "mean_log1p_expr": 3.6362,
      "detect_fraction": 0.9167
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_5",
      "rank": 1,
      "gene": "CXCL14",
      "score_log1p_diff": 3.2841,
      "mean_log1p_expr": 3.3311,
      "detect_fraction": 0.9074
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_18",
      "rank": 1,
      "gene": "CRYAB",
      "score_log1p_diff": 2.9736,
      "mean_log1p_expr": 3.2282,
      "detect_fraction": 0.9412
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_12",
      "rank": 1,
      "gene": "CXCL8",
      "score_log1p_diff": 2.9602,
      "mean_log1p_expr": 3.2221,
      "detect_fraction": 0.9886
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_6",
      "rank": 1,
      "gene": "HLA-DRA",
      "score_log1p_diff": 2.9507,
      "mean_log1p_expr": 3.4896,
      "detect_fraction": 0.9862
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_13",
      "rank": 1,
      "gene": "IGFBP7",
      "score_log1p_diff": 2.9128,
      "mean_log1p_expr": 3.1997,
      "detect_fraction": 1
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_14",
      "rank": 1,
      "gene": "CD74",
      "score_log1p_diff": 2.495,
      "mean_log1p_expr": 4.2684,
      "detect_fraction": 1
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_9",
      "rank": 1,
      "gene": "IL1B",
      "score_log1p_diff": 2.1278,
      "mean_log1p_expr": 2.2431,
      "detect_fraction": 0.7344
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_3",
      "rank": 1,
      "gene": "IL32",
      "score_log1p_diff": 2.1081,
      "mean_log1p_expr": 3.0262,
      "detect_fraction": 0.9839
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_2",
      "rank": 1,
      "gene": "CCL5",
      "score_log1p_diff": 2.0191,
      "mean_log1p_expr": 2.3941,
      "detect_fraction": 0.9596
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_7",
      "rank": 1,
      "gene": "GNLY",
      "score_log1p_diff": 1.9958,
      "mean_log1p_expr": 2.1249,
      "detect_fraction": 0.6929
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_4",
      "rank": 1,
      "gene": "CD3E",
      "score_log1p_diff": 1.2776,
      "mean_log1p_expr": 1.8996,
      "detect_fraction": 0.9727
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_1",
      "rank": 1,
      "gene": "IL7R",
      "score_log1p_diff": 1.0005,
      "mean_log1p_expr": 1.3582,
      "detect_fraction": 0.7826
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_19",
      "rank": 2,
      "gene": "IGHV4-31",
      "score_log1p_diff": 7.0658,
      "mean_log1p_expr": 7.092,
      "detect_fraction": 1
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_21",
      "rank": 2,
      "gene": "IGHV1-2",
      "score_log1p_diff": 7.0612,
      "mean_log1p_expr": 7.1471,
      "detect_fraction": 1
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_22",
      "rank": 2,
      "gene": "IGKV1-12",
      "score_log1p_diff": 6.0873,
      "mean_log1p_expr": 6.0937,
      "detect_fraction": 1
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_20",
      "rank": 2,
      "gene": "IGHV3-64",
      "score_log1p_diff": 5.736,
      "mean_log1p_expr": 5.7612,
      "detect_fraction": 1
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_16",
      "rank": 2,
      "gene": "IGHG1",
      "score_log1p_diff": 4.7191,
      "mean_log1p_expr": 5.2464,
      "detect_fraction": 0.9667
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_8",
      "rank": 2,
      "gene": "IGKC",
      "score_log1p_diff": 4.4305,
      "mean_log1p_expr": 4.5972,
      "detect_fraction": 0.9023
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_11",
      "rank": 2,
      "gene": "COL1A2",
      "score_log1p_diff": 3.3369,
      "mean_log1p_expr": 3.3743,
      "detect_fraction": 0.9451
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_5",
      "rank": 2,
      "gene": "CD9",
      "score_log1p_diff": 3.2003,
      "mean_log1p_expr": 3.5024,
      "detect_fraction": 0.9753
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_17",
      "rank": 2,
      "gene": "TPSB2",
      "score_log1p_diff": 3.1257,
      "mean_log1p_expr": 3.1257,
      "detect_fraction": 1
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_10",
      "rank": 2,
      "gene": "KRT6A",
      "score_log1p_diff": 2.9771,
      "mean_log1p_expr": 3.2026,
      "detect_fraction": 0.9429
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_6",
      "rank": 2,
      "gene": "CD74",
      "score_log1p_diff": 2.8237,
      "mean_log1p_expr": 4.4396,
      "detect_fraction": 0.9931
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_15",
      "rank": 2,
      "gene": "TAGLN",
      "score_log1p_diff": 2.7151,
      "mean_log1p_expr": 2.7729,
      "detect_fraction": 0.9722
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_12",
      "rank": 2,
      "gene": "G0S2",
      "score_log1p_diff": 2.6223,
      "mean_log1p_expr": 2.7771,
      "detect_fraction": 0.9432
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_18",
      "rank": 2,
      "gene": "CLU",
      "score_log1p_diff": 2.2933,
      "mean_log1p_expr": 2.3963,
      "detect_fraction": 0.7647
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_14",
      "rank": 2,
      "gene": "HLA-DRA",
      "score_log1p_diff": 2.2819,
      "mean_log1p_expr": 2.9915,
      "detect_fraction": 0.8947
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_9",
      "rank": 2,
      "gene": "CXCL8",
      "score_log1p_diff": 2.0584,
      "mean_log1p_expr": 2.3189,
      "detect_fraction": 0.6953
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_13",
      "rank": 2,
      "gene": "HSPG2",
      "score_log1p_diff": 2.0483,
      "mean_log1p_expr": 2.0829,
      "detect_fraction": 0.8723
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_7",
      "rank": 2,
      "gene": "CCL5",
      "score_log1p_diff": 1.8774,
      "mean_log1p_expr": 2.321,
      "detect_fraction": 0.8714
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_2",
      "rank": 2,
      "gene": "NKG7",
      "score_log1p_diff": 1.6447,
      "mean_log1p_expr": 1.8804,
      "detect_fraction": 0.9091
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_3",
      "rank": 2,
      "gene": "TNFRSF4",
      "score_log1p_diff": 1.5053,
      "mean_log1p_expr": 1.6073,
      "detect_fraction": 0.8548
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_4",
      "rank": 2,
      "gene": "CD3D",
      "score_log1p_diff": 1.246,
      "mean_log1p_expr": 1.7179,
      "detect_fraction": 0.9617
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_1",
      "rank": 2,
      "gene": "SARAF",
      "score_log1p_diff": 0.8679,
      "mean_log1p_expr": 2.2904,
      "detect_fraction": 0.9855
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_19",
      "rank": 3,
      "gene": "IGHV4-28",
      "score_log1p_diff": 5.4225,
      "mean_log1p_expr": 5.4343,
      "detect_fraction": 1
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_22",
      "rank": 3,
      "gene": "IGHG1",
      "score_log1p_diff": 5.3303,
      "mean_log1p_expr": 5.9179,
      "detect_fraction": 1
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_20",
      "rank": 3,
      "gene": "IGLC1",
      "score_log1p_diff": 5.1526,
      "mean_log1p_expr": 5.3071,
      "detect_fraction": 1
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_21",
      "rank": 3,
      "gene": "IGKC",
      "score_log1p_diff": 5.0448,
      "mean_log1p_expr": 5.4762,
      "detect_fraction": 1
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_16",
      "rank": 3,
      "gene": "IGLV3-25",
      "score_log1p_diff": 3.842,
      "mean_log1p_expr": 3.9178,
      "detect_fraction": 0.7333
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_8",
      "rank": 3,
      "gene": "IGKV3-15",
      "score_log1p_diff": 3.3605,
      "mean_log1p_expr": 3.55,
      "detect_fraction": 0.7594
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_17",
      "rank": 3,
      "gene": "CPA3",
      "score_log1p_diff": 3.1255,
      "mean_log1p_expr": 3.1255,
      "detect_fraction": 1
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_11",
      "rank": 3,
      "gene": "COL3A1",
      "score_log1p_diff": 3.1108,
      "mean_log1p_expr": 3.1473,
      "detect_fraction": 0.9011
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_5",
      "rank": 3,
      "gene": "KRT17",
      "score_log1p_diff": 3.0067,
      "mean_log1p_expr": 3.2391,
      "detect_fraction": 0.9691
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_15",
      "rank": 3,
      "gene": "SPARC",
      "score_log1p_diff": 2.6869,
      "mean_log1p_expr": 2.9946,
      "detect_fraction": 0.8611
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_10",
      "rank": 3,
      "gene": "PERP",
      "score_log1p_diff": 2.3554,
      "mean_log1p_expr": 2.749,
      "detect_fraction": 0.9714
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_9",
      "rank": 3,
      "gene": "HLA-DRA",
      "score_log1p_diff": 2.0489,
      "mean_log1p_expr": 2.6706,
      "detect_fraction": 0.8984
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_13",
      "rank": 3,
      "gene": "COL4A1",
      "score_log1p_diff": 2.0297,
      "mean_log1p_expr": 2.1179,
      "detect_fraction": 0.9362
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_18",
      "rank": 3,
      "gene": "FOS",
      "score_log1p_diff": 2.0001,
      "mean_log1p_expr": 3.2668,
      "detect_fraction": 1
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_6",
      "rank": 3,
      "gene": "HLA-DRB1",
      "score_log1p_diff": 1.9821,
      "mean_log1p_expr": 2.5574,
      "detect_fraction": 0.9862
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_14",
      "rank": 3,
      "gene": "CORO1A",
      "score_log1p_diff": 1.8681,
      "mean_log1p_expr": 2.7171,
      "detect_fraction": 1
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_12",
      "rank": 3,
      "gene": "IL1B",
      "score_log1p_diff": 1.8533,
      "mean_log1p_expr": 2.0232,
      "detect_fraction": 0.9091
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_7",
      "rank": 3,
      "gene": "NKG7",
      "score_log1p_diff": 1.7658,
      "mean_log1p_expr": 2.0409,
      "detect_fraction": 0.9143
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_3",
      "rank": 3,
      "gene": "BATF",
      "score_log1p_diff": 1.437,
      "mean_log1p_expr": 1.7197,
      "detect_fraction": 0.9086
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_2",
      "rank": 3,
      "gene": "CD8A",
      "score_log1p_diff": 1.3536,
      "mean_log1p_expr": 1.419,
      "detect_fraction": 0.8081
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_4",
      "rank": 3,
      "gene": "KLRB1",
      "score_log1p_diff": 1.2229,
      "mean_log1p_expr": 1.3807,
      "detect_fraction": 0.7923
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_1",
      "rank": 3,
      "gene": "CXCR4",
      "score_log1p_diff": 0.8159,
      "mean_log1p_expr": 1.8025,
      "detect_fraction": 0.8937
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_22",
      "rank": 4,
      "gene": "IGKC",
      "score_log1p_diff": 5.25,
      "mean_log1p_expr": 5.7011,
      "detect_fraction": 1
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_20",
      "rank": 4,
      "gene": "IGHG1",
      "score_log1p_diff": 5.0919,
      "mean_log1p_expr": 5.657,
      "detect_fraction": 1
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_21",
      "rank": 4,
      "gene": "IGHG1",
      "score_log1p_diff": 5.0438,
      "mean_log1p_expr": 5.6117,
      "detect_fraction": 1
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_19",
      "rank": 4,
      "gene": "IGHG1",
      "score_log1p_diff": 4.8419,
      "mean_log1p_expr": 5.4062,
      "detect_fraction": 1
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_16",
      "rank": 4,
      "gene": "IGLV3-19",
      "score_log1p_diff": 3.7031,
      "mean_log1p_expr": 3.7782,
      "detect_fraction": 0.7667
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_11",
      "rank": 4,
      "gene": "SPARC",
      "score_log1p_diff": 3.0785,
      "mean_log1p_expr": 3.2945,
      "detect_fraction": 0.9341
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_8",
      "rank": 4,
      "gene": "SSR4",
      "score_log1p_diff": 3.0297,
      "mean_log1p_expr": 4.0152,
      "detect_fraction": 0.985
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_5",
      "rank": 4,
      "gene": "PERP",
      "score_log1p_diff": 2.92,
      "mean_log1p_expr": 3.2007,
      "detect_fraction": 0.9877
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_15",
      "rank": 4,
      "gene": "CALD1",
      "score_log1p_diff": 2.6553,
      "mean_log1p_expr": 2.8964,
      "detect_fraction": 0.9722
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_10",
      "rank": 4,
      "gene": "S100A2",
      "score_log1p_diff": 2.314,
      "mean_log1p_expr": 2.518,
      "detect_fraction": 0.8762
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_9",
      "rank": 4,
      "gene": "LYZ",
      "score_log1p_diff": 2.0366,
      "mean_log1p_expr": 2.0451,
      "detect_fraction": 0.7422
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_17",
      "rank": 4,
      "gene": "CLU",
      "score_log1p_diff": 1.979,
      "mean_log1p_expr": 2.0807,
      "detect_fraction": 1
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_13",
      "rank": 4,
      "gene": "PLVAP",
      "score_log1p_diff": 1.9733,
      "mean_log1p_expr": 1.9749,
      "detect_fraction": 0.9149
    },
    {
      "sample_id": "ESCC-111-07-1A",
      "cluster": "cluster_18",
      "rank": 4,
      "gene": "ATF3",
      "score_log1p_diff": 1.9689,
      "mean_log1p_expr": 2.511,
      "detect_fraction": 1
    }
  ],
  "source_tables": {
    "sample_index": "data/human_immune_atlas/analysis/cancerscem_deep/cancerscem_sample_index.tsv",
    "cluster_qc": "data/human_immune_atlas/analysis/cancerscem_deep/cancerscem_cluster_qc.tsv",
    "program_scores": "data/human_immune_atlas/analysis/cancerscem_deep/cancerscem_program_scores.tsv",
    "cluster_markers": "data/human_immune_atlas/analysis/cancerscem_deep/cancerscem_cluster_markers.tsv"
  }
}