[
  {
    "pmid": "42338463",
    "doi": "10.1093/noajnl/vdaf012",
    "year": 2026,
    "title": "Chemotherapy neurotoxicity and aging: Uncovering shared central nervous system pathologies and potential interventions.",
    "authors": [
      "Nunez MS",
      "Gibson EM"
    ],
    "journal": "Neuro-oncology advances",
    "journalAbbr": "Neurooncol Adv",
    "topic": "senescence",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Palo Alto, California, USA."
    ],
    "keywords": [
      "senescence"
    ],
    "abstract": "PubMed record in Neuro-oncology advances (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42333936",
    "doi": "10.1111/acel.70597",
    "year": 2026,
    "title": "Cellular Heterogeneity During Arterial Aging.",
    "authors": [
      "Xu H",
      "Mendez PL",
      "Kasakovski D",
      "Sluimer J"
    ],
    "journal": "Aging cell",
    "journalAbbr": "Aging Cell",
    "topic": "singlecell",
    "country": "Germany",
    "countryCode": "DE",
    "affiliation": [
      "Department of Pathology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands.",
      "Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Berlin, Germany."
    ],
    "keywords": [
      "senescence",
      "inflammaging",
      "Humans",
      "Aging",
      "Arteries",
      "Animals"
    ],
    "abstract": "PubMed record in Aging cell (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42327492",
    "doi": "10.1016/j.bioactmat.2026.06.011",
    "year": 2026,
    "title": "Neonatal muscle-derived extracellular vesicles containing miR-542-3p rejuvenate aged skeletal muscle via a functional microneedle patch.",
    "authors": [
      "Yuan F",
      "Chen Y",
      "Li W",
      "Zhang L",
      "Du R",
      "Xu S",
      "Hu Z",
      "Zhang T",
      "Qin L",
      "Lu H",
      "Li C"
    ],
    "journal": "Bioactive materials",
    "journalAbbr": "Bioact Mater",
    "topic": "senescence",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Department of Sports Medicine, Xiangya Hospital, Central South University, Changsha, China.",
      "Department of Spine Surgery and Orthopaedics, Xiangya Hospital, Central South University, Changsha, China."
    ],
    "keywords": [
      "senescence",
      "mitochondria"
    ],
    "abstract": "PubMed record in Bioactive materials (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42327386",
    "doi": "10.1016/j.bbih.2026.101269",
    "year": 2026,
    "title": "Maternal health behavior during pregnancy mediates the relationship between maternal stress and newborn telomere length.",
    "authors": [
      "de Punder K",
      "Godara M",
      "Speckle N",
      "Martens DS",
      "Klawitter H",
      "Moog NK",
      "Lazarides C",
      "La Nave SG",
      "Henrich W",
      "Heim C",
      "Braun T",
      "Lindsay K"
    ],
    "journal": "Brain, behavior, & immunity - health",
    "journalAbbr": "Brain Behav Immun Health",
    "topic": "telomere",
    "country": "Germany",
    "countryCode": "DE",
    "affiliation": [
      "Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Medical Psychology, Berlin, Germany.",
      "Department of Psychology, Clinical Psychology-II, University of Innsbruck, Innsbruck, Austria."
    ],
    "keywords": [
      "telomere",
      "lifespan"
    ],
    "abstract": "PubMed record in Brain, behavior, & immunity - health (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42327006",
    "doi": "10.1016/j.reth.2026.101146",
    "year": 2026,
    "title": "Long-term expandable auricular chondrocytes reveal a conserved nine-gene decline module underlying senescence-independent dedifferentiation.",
    "authors": [
      "Alemujiang D",
      "Tsuji N",
      "Sakamoto T",
      "Chu YY",
      "Hoshi K",
      "Hikita A"
    ],
    "journal": "Regenerative therapy",
    "journalAbbr": "Regen Ther",
    "topic": "senescence",
    "country": "Japan",
    "countryCode": "JP",
    "affiliation": [
      "Department of Oral and Maxillofacial Surgery, Dentistry and Orthodontics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.",
      "Department of Tissue Engineering, The University of Tokyo Hospital, Tokyo, Japan."
    ],
    "keywords": [
      "senescence"
    ],
    "abstract": "PubMed record in Regenerative therapy (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42313933",
    "doi": "10.1073/pnas.2426990123",
    "year": 2026,
    "title": "Endothelial KLF4 depletion drives age-related neurovascular dysfunction and neuropsychiatric impairment.",
    "authors": [
      "Dhar M",
      "Vázquez-Rosa E",
      "Chaubey K",
      "Miller E",
      "Corella SG",
      "Chakraborty S",
      "Tripathi SJ",
      "Das T",
      "Liao X",
      "Alosman MA",
      "Fang H",
      "Koh Y"
    ],
    "journal": "Proceedings of the National Academy of Sciences of the United States of America",
    "journalAbbr": "Proc Natl Acad Sci U S A",
    "topic": "singlecell",
    "country": "Unspecified",
    "countryCode": "--",
    "affiliation": [
      "Department of Psychiatry, Case Western Reserve University, Cleveland, OH 44106.",
      "Brain Health Medicines Center, Harrington Discovery Institute, University Hospitals Cleveland Medical Center, Cleveland, OH 44106."
    ],
    "keywords": [
      "senescence",
      "Animals",
      "Kruppel-Like Factor 4",
      "Mice",
      "Aging",
      "Kruppel-Like Transcription Factors"
    ],
    "abstract": "PubMed record in Proceedings of the National Academy of Sciences of the United States of America (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42300249",
    "doi": "10.1111/gtc.70127",
    "year": 2026,
    "title": "A Persistent Homology Approach Enables Single-Cell Detection of Chromatin Spatial Organization Changes During Pathological Senescence Transition.",
    "authors": [
      "Furuya K",
      "Umeno Y",
      "Ikura M",
      "Ikura Y",
      "Nishikawa S",
      "Ikura T"
    ],
    "journal": "Genes to cells : devoted to molecular & cellular mechanisms",
    "journalAbbr": "Genes Cells",
    "topic": "singlecell",
    "country": "Japan",
    "countryCode": "JP",
    "affiliation": [
      "Laboratory of Genome Maintenance, Department of Genome Biology, Radiation Biology Center, Graduate School of Biostudies, Kyoto University, Yoshida Konoe-cho, Sakyo-ku, Kyoto, Japan.",
      "Laboratory of Nano-Micro Mechanophysics, Department of Fundamental Engineering, Institute of Industrial Science, The University of Tokyo, Tokyo, Japan."
    ],
    "keywords": [
      "senescence",
      "Cellular Senescence",
      "Chromatin",
      "Histones",
      "Single-Cell Analysis",
      "Humans"
    ],
    "abstract": "PubMed record in Genes to cells : devoted to molecular & cellular mechanisms (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42281947",
    "doi": "10.1016/j.ibneur.2026.05.009",
    "year": 2026,
    "title": "DNA methylation-estimated phenotypes, telomere length, aging and risk of intracranial aneurysms: Evidence from genetic studies.",
    "authors": [
      "Zhang X",
      "Maimaiti A",
      "Xie M",
      "Turhon M",
      "Yalikun N",
      "Liang W"
    ],
    "journal": "IBRO neuroscience reports",
    "journalAbbr": "IBRO Neurosci Rep",
    "topic": "telomere",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Department of Neurosurgery, The Fourth Affiliated Hospital of Xinjiang Medical University (Xinjiang Uyhgur Autonomous Region Hospital of Traditional Chinese Medicine), Urumqi, Xinjiang, PR China.",
      "Department of Neurosurgery, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, PR China."
    ],
    "keywords": [
      "telomere",
      "DNA methylation",
      "longevity"
    ],
    "abstract": "PubMed record in IBRO neuroscience reports (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42261812",
    "doi": "10.1080/01443615.2026.2681760",
    "year": 2026,
    "title": "Delayed childbearing and reproductive ageing: a narrative review.",
    "authors": [
      "Yang D",
      "Huang H",
      "He Y"
    ],
    "journal": "Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology",
    "journalAbbr": "J Obstet Gynaecol",
    "topic": "mito",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Department of Reproductive Medicine, West China Second University Hospital, Sichuan University, Chengdu, China.",
      "Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, China."
    ],
    "keywords": [
      "mitochondria",
      "Humans",
      "Female",
      "Pregnancy",
      "Advanced Maternal Age",
      "Aging"
    ],
    "abstract": "PubMed record in Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42238310",
    "doi": "10.1016/j.gendis.2025.101980",
    "year": 2026,
    "title": "Obesity accelerates aging: Mechanisms and therapeutic implications.",
    "authors": [
      "Zhang R",
      "Liu L",
      "Shi X",
      "Ren Y"
    ],
    "journal": "Genes & diseases",
    "journalAbbr": "Genes Dis",
    "topic": "telomere",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.",
      "The First College of Clinical Medicine, Chongqing Medical University, Chongqing 400016, China."
    ],
    "keywords": [
      "telomere",
      "mitochondria"
    ],
    "abstract": "PubMed record in Genes & diseases (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42232748",
    "doi": "10.1016/j.bioactmat.2026.05.016",
    "year": 2026,
    "title": "A sustained NAD+ supplementation-biosynthesis nanoplatform for metabolic restoration in aged bone regeneration.",
    "authors": [
      "Xie F",
      "He Z",
      "Xu S",
      "Bai X",
      "Wang X",
      "Zhang F",
      "Yuan Y",
      "Liu C",
      "Niu D"
    ],
    "journal": "Bioactive materials",
    "journalAbbr": "Bioact Mater",
    "topic": "nad",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Key Laboratory for Ultrafine Materials of Ministry of Education, Engineering Research Center for Biomedical Materials of Ministry of Education, East China University of Science and Technology, Shanghai, 200237, PR China.",
      "Excellent Research Group Project of National Natural Science Foundation of China, East China University of Science and Technology, Shanghai, 200237, PR China."
    ],
    "keywords": [
      "NAD"
    ],
    "abstract": "PubMed record in Bioactive materials (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42222959",
    "doi": "10.1152/ajpheart.00007.2026",
    "year": 2026,
    "title": "Growth arrest of thoracic aortic aneurysms in aging Marfan mice.",
    "authors": [
      "Means CW",
      "Mays G",
      "Yeung N",
      "Cavinato C",
      "Manning EP",
      "Lam TT",
      "Humphrey JD",
      "Weiss D"
    ],
    "journal": "American journal of physiology. Heart and circulatory physiology",
    "journalAbbr": "Am J Physiol Heart Circ Physiol",
    "topic": "caloric",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Department of Biomedical Engineering, Yale University, New Haven, Connecticut, United States.",
      "School of Biological Sciences, University of Cambridge, Cambridge, United Kingdom."
    ],
    "keywords": [
      "mTOR",
      "Animals",
      "Marfan Syndrome",
      "Aortic Aneurysm, Thoracic",
      "Disease Models, Animal",
      "Fibrillin-1"
    ],
    "abstract": "PubMed record in American journal of physiology. Heart and circulatory physiology (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42222188",
    "doi": "10.3389/fragi.2026.1791853",
    "year": 2026,
    "title": "Dietary pyrroloquinoline quinone and spermidine in healthy longevity: targeting the hallmarks of aging.",
    "authors": [
      "Numaguchi T",
      "Nakamura M",
      "Koshizawa T",
      "Mohamad Ishak NS",
      "Hashimoto K"
    ],
    "journal": "Frontiers in aging",
    "journalAbbr": "Front Aging",
    "topic": "nad",
    "country": "Japan",
    "countryCode": "JP",
    "affiliation": [
      "Niigata Research Laboratory, Mitsubishi Gas Chemical Company, Inc., Niigata, Japan."
    ],
    "keywords": [
      "autophagy",
      "proteostasis",
      "mitochondria",
      "longevity",
      "lifespan",
      "healthspan"
    ],
    "abstract": "PubMed record in Frontiers in aging (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42220642",
    "doi": "10.1016/j.bioactmat.2026.05.030",
    "year": 2026,
    "title": "In vivo circRNA-engineered macrophages mediate localized MMP9 neutralization to rejuvenate aged bone.",
    "authors": [
      "Zhu D",
      "Ling S",
      "Fang H",
      "Yang Q",
      "Du Y",
      "Cui W",
      "Chen Y"
    ],
    "journal": "Bioactive materials",
    "journalAbbr": "Bioact Mater",
    "topic": "senescence",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Department of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 600 Yishan Road, Shanghai, 200233, PR China.",
      "Department of Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai, 200025, PR China."
    ],
    "keywords": [
      "senescence",
      "stem cell"
    ],
    "abstract": "PubMed record in Bioactive materials (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42214504",
    "doi": "10.1016/j.arr.2026.103189",
    "year": 2026,
    "title": "Spatial transcriptomics and multi-omics approach to decipher age-related tissue microenvironments and therapeutics in neurodegeneration and aging.",
    "authors": [
      "Lakra A",
      "Singh N",
      "Vashisth S",
      "Ambasta RK",
      "Kumar P"
    ],
    "journal": "Ageing research reviews",
    "journalAbbr": "Ageing Res Rev",
    "topic": "singlecell",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Molecular Neuroscience and Functional Genomics Laboratory, Department of Biotechnology, Delhi Technological University (Formerly DCE), Delhi 110042, India.",
      "Department of Medicine, School of Medicine, Vanderbilt University Medical Center, Vanderbilt University, TN, USA. Electronic address: rashmi.ambasta@vumc.org."
    ],
    "keywords": [
      "biomarkers",
      "Animals",
      "Humans",
      "Aging",
      "Cellular Microenvironment",
      "Multiomics"
    ],
    "abstract": "PubMed record in Ageing research reviews (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42211890",
    "doi": "10.1007/s10616-026-00947-3",
    "year": 2026,
    "title": "Downregulation of FLT1 delays vascular aging by suppressing MAPK signaling pathway activation in vascular smooth muscle cells​.",
    "authors": [
      "Fu L",
      "Duan J",
      "Ge M",
      "Fan Y",
      "Ou Y"
    ],
    "journal": "Cytotechnology",
    "journalAbbr": "Cytotechnology",
    "topic": "senescence",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Department of Geriatrics, The Third Hospital of Changsha, Changsha City, 410000 Hunan Province China.",
      "Department of Neurology, Changsha Hospital of Traditional Chinese Medicine (Changsha Eighth Hospital), No.22, Xingsha Avenue, Changsha County, Changsha City, 410000 Hunan Province China."
    ],
    "keywords": [
      "senescence",
      "NAD"
    ],
    "abstract": "PubMed record in Cytotechnology (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42208498",
    "doi": "10.1016/j.cell.2026.04.020",
    "year": 2026,
    "title": "Mesenchymal drift: A convergent framework for the hallmarks of aging.",
    "authors": [
      "Lu JY",
      "Tu WB",
      "Ma S",
      "Ma Z",
      "Imaz-Rosshandler I",
      "Weng M",
      "Qu J",
      "Rodriguez Esteban C",
      "Reddy P",
      "Liu GH",
      "Izpisua Belmonte JC"
    ],
    "journal": "Cell",
    "journalAbbr": "Cell",
    "topic": "genetherapy",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Altos Labs, San Diego, CA, USA.",
      "State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China."
    ],
    "keywords": [
      "reprogramming",
      "Aging",
      "Humans",
      "Animals",
      "Epithelial-Mesenchymal Transition",
      "Cellular Reprogramming"
    ],
    "abstract": "PubMed record in Cell (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42203047",
    "doi": "10.1016/j.bbr.2026.116296",
    "year": 2026,
    "title": "Thyronines and thyronamines: dual modulators of synaptic plasticity, cognitive decline, and geriatric depression in the aging brain.",
    "authors": [
      "Alruwaili NS",
      "Al-Kuraishy HM",
      "Fawzy MN",
      "Al-Gareeb AI",
      "Fahad EH",
      "Batiha GE"
    ],
    "journal": "Behavioural brain research",
    "journalAbbr": "Behav Brain Res",
    "topic": "caloric",
    "country": "Unspecified",
    "countryCode": "--",
    "affiliation": [
      "Department of Internal Medicine, College of Medicine, Northern Border University, Arar, Saudi Arabia. Electronic address: Nahi.Alruwaili@nbu.edu.sa.",
      "Department of Clinical Pharmacology and Medicine, College of Medicine, Mustansiriyah University, Baghdad, Iraq. Electronic address: haydermutter@uomustansiriyah.edu.iq."
    ],
    "keywords": [
      "mTOR",
      "autophagy",
      "mitochondria",
      "Animals",
      "Aging",
      "Humans"
    ],
    "abstract": "PubMed record in Behavioural brain research (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42173209",
    "doi": "10.1016/j.critrevonc.2026.105385",
    "year": 2026,
    "title": "Bidirectional roles of senescence in tumor-infiltrating immune cells: Mechanisms, impact on immunotherapy, and therapeutic strategies.",
    "authors": [
      "Zhao R",
      "Li Y",
      "Zhu R",
      "Zong R",
      "Sun M",
      "Liu M",
      "Guo H"
    ],
    "journal": "Critical reviews in oncology/hematology",
    "journalAbbr": "Crit Rev Oncol Hematol",
    "topic": "senescence",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Shandong University of Traditional Chinese Medicine, Jinan 250355, China. Electronic address: zrh19588956379@163.com.",
      "Shandong University of Traditional Chinese Medicine, Jinan 250355, China. Electronic address: 15668417715@163.com."
    ],
    "keywords": [
      "senescence",
      "reprogramming",
      "Humans",
      "Immunotherapy",
      "Tumor Microenvironment",
      "Neoplasms"
    ],
    "abstract": "PubMed record in Critical reviews in oncology/hematology (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42165002",
    "doi": "10.1016/j.bioactmat.2026.04.038",
    "year": 2026,
    "title": "Reconstructing protein conformations to activate follicular enzyme-nutrient reservoirs for reversing follicle aging.",
    "authors": [
      "Ling S",
      "Liu M",
      "Meng C",
      "Huo K",
      "Wang Y",
      "Zhang Y",
      "Wei Y",
      "Zhou L",
      "Du Y",
      "Cui W"
    ],
    "journal": "Bioactive materials",
    "journalAbbr": "Bioact Mater",
    "topic": "senescence",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Department of Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, PR China.",
      "School of Clinical Medicine, Shanghai Jiao Tong University School of Medicine, 227 Chongqing South Road, Huangpu District, Shanghai, 200025, PR China."
    ],
    "keywords": [
      "senescence",
      "stem cell"
    ],
    "abstract": "PubMed record in Bioactive materials (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42144205",
    "doi": "10.1016/j.exger.2026.113177",
    "year": 2026,
    "title": "Microglial senescence and epigenetic reprogramming in alzheimer's disease: An immunometabolic perspective.",
    "authors": [
      "Ma J",
      "Yang B",
      "Jiang X",
      "Wang L",
      "Wei W",
      "Cao Y",
      "Li H"
    ],
    "journal": "Experimental gerontology",
    "journalAbbr": "Exp Gerontol",
    "topic": "senescence",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China.",
      "Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China; Beijing University of Chinese Medicine, Beijing, China."
    ],
    "keywords": [
      "senescence",
      "mitochondria",
      "reprogramming",
      "Alzheimer Disease",
      "Humans",
      "Microglia"
    ],
    "abstract": "PubMed record in Experimental gerontology (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42142553",
    "doi": "10.1016/j.jep.2026.121873",
    "year": 2026,
    "title": "Jintiange ameliorates age-related sarcopenia by inhibiting the cGAS-STING signaling pathway via maintaining mitochondrial homeostasis.",
    "authors": [
      "Xu Y",
      "Li XL",
      "Guo YX",
      "Wu RB",
      "He MC",
      "Zhang Y"
    ],
    "journal": "Journal of ethnopharmacology",
    "journalAbbr": "J Ethnopharmacol",
    "topic": "senescence",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Spine Disease Research Institute, Longhua Hospital affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China.",
      "Development Research Institute of Science and Technology, University of Shanghai for Science and Technology, Shanghai, 200090, China."
    ],
    "keywords": [
      "senescence",
      "autophagy",
      "mitochondria",
      "Animals",
      "Male",
      "Sarcopenia"
    ],
    "abstract": "PubMed record in Journal of ethnopharmacology (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42140441",
    "doi": "10.1016/j.arr.2026.103181",
    "year": 2026,
    "title": "The Hallmarks of aging: Paradigms and scientific progress.",
    "authors": [
      "García-Barranquero P",
      "Luque VJ"
    ],
    "journal": "Ageing research reviews",
    "journalAbbr": "Ageing Res Rev",
    "topic": "mito",
    "country": "Spain",
    "countryCode": "ES",
    "affiliation": [
      "Department of Philosophy, University of Malaga, Malaga, Spain. Electronic address: pablogarcia@uma.es.",
      "Department of Philosophy, University of Valencia, Valencia, Spain."
    ],
    "keywords": [
      "Aging",
      "Humans",
      "Animals",
      "Geroscience"
    ],
    "abstract": "PubMed record in Ageing research reviews (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42134737",
    "doi": "10.1016/j.arr.2026.103175",
    "year": 2026,
    "title": "Cellular senescence as a systems-level driver of cardiovascular ageing.",
    "authors": [
      "Wang MM",
      "Liu T",
      "Xu CQ",
      "Zhong YL",
      "Liang ZQ",
      "Li J",
      "Cao YB",
      "Chen J"
    ],
    "journal": "Ageing research reviews",
    "journalAbbr": "Ageing Res Rev",
    "topic": "singlecell",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Institute of Vascular Anomalies, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200082, China.",
      "Department of Hepatobiliary Surgery, Shandong Provincial Hospital Heze Branch, Heze, China."
    ],
    "keywords": [
      "senescence",
      "telomere",
      "mitochondria",
      "reprogramming",
      "Humans",
      "Cellular Senescence"
    ],
    "abstract": "PubMed record in Ageing research reviews (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42134555",
    "doi": "10.1016/j.toxicon.2026.109152",
    "year": 2026,
    "title": "Neural and metabolic mechanisms of emetogenic foodborne toxins via the brain-gut axis in ageing and cachexia.",
    "authors": [
      "Xu H",
      "Li M",
      "Liu Y",
      "Nie G",
      "Li M",
      "Meng Z"
    ],
    "journal": "Toxicon : official journal of the International Society on Toxinology",
    "journalAbbr": "Toxicon",
    "topic": "senescence",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "School of Public Health, Guangxi Medical University, Nanning, Guangxi, 530021, China.",
      "College of Food Science and Technology, Huazhong Agricultural University, Wuhan, Hubei Province, 430070, China."
    ],
    "keywords": [
      "senescence",
      "reprogramming",
      "Humans",
      "Aging",
      "Animals",
      "Cachexia"
    ],
    "abstract": "PubMed record in Toxicon : official journal of the International Society on Toxinology (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42134515",
    "doi": "10.1016/j.cellsig.2026.112577",
    "year": 2026,
    "title": "The role of macrophage senescence in cardiovascular diseases.",
    "authors": [
      "Sun Y",
      "Chang Y",
      "Lin H",
      "Fan G",
      "Li L",
      "Ma C"
    ],
    "journal": "Cellular signalling",
    "journalAbbr": "Cell Signal",
    "topic": "senescence",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China; National Clinical Research Center for Chinese Medicine, Tianjin, China; State Key Laboratory of Modern Chinese Medicine, Key Laboratory of Pharmacology of Traditional Chinese Medical Formulae for the Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin, China.",
      "First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China; National Clinical Research Center for Chinese Medicine, Tianjin, China; State Key Laboratory of Modern Chinese Medicine, Key Laboratory of Pharmacology of Traditional Chinese Medical Formulae for the Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin, China. Electronic address: lilan_0813@163.com."
    ],
    "keywords": [
      "senescence",
      "telomere",
      "mitochondria",
      "Humans",
      "Macrophages",
      "Cellular Senescence"
    ],
    "abstract": "PubMed record in Cellular signalling (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42128044",
    "doi": "10.1016/j.exer.2026.111064",
    "year": 2026,
    "title": "Metabolic reprogramming and mitochondrial dynamics: Novel therapeutic perspectives for age-related macular degeneration.",
    "authors": [
      "Hu Z",
      "Qi H",
      "Dong X",
      "Tian Y",
      "Sun M",
      "Jia X",
      "Yu H"
    ],
    "journal": "Experimental eye research",
    "journalAbbr": "Exp Eye Res",
    "topic": "singlecell",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Department of Pathophysiology, College of Basic Medical Sciences, Jilin University, Changchun, 130021, China; The First School of Clinical Medicine of Jilin University, Changchun, 130033, China.",
      "Department of Pathophysiology, College of Basic Medical Sciences, Jilin University, Changchun, 130021, China."
    ],
    "keywords": [
      "mTOR",
      "mitochondria",
      "reprogramming",
      "Humans",
      "Mitochondrial Dynamics",
      "Metabolic Reprogramming"
    ],
    "abstract": "PubMed record in Experimental eye research (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42127842",
    "doi": "10.1016/j.schres.2026.04.020",
    "year": 2026,
    "title": "The role of global DNA methylation and epigenetic aging in the suicidality of patients with schizophrenia.",
    "authors": [
      "Nader G",
      "Raymond R",
      "Trad R",
      "Ducharme M",
      "Graff A",
      "Gerretsen P",
      "Fischer C",
      "De Luca V"
    ],
    "journal": "Schizophrenia research",
    "journalAbbr": "Schizophr Res",
    "topic": "telomere",
    "country": "Canada",
    "countryCode": "CA",
    "affiliation": [
      "Centre for Addiction and Mental Health, Toronto, ON, Canada; University of Toronto, Temerty Faculty of Medicine, Department of Pharmacology & Toxicology, Toronto, ON, Canada.",
      "Centre for Addiction and Mental Health, Toronto, ON, Canada."
    ],
    "keywords": [
      "telomere",
      "epigenetic clock",
      "DNA methylation",
      "Humans",
      "DNA Methylation",
      "Schizophrenia"
    ],
    "abstract": "PubMed record in Schizophrenia research (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42125221",
    "doi": "10.1016/j.vas.2026.100675",
    "year": 2026,
    "title": "Effect of Echinacea purpurea on cytokine gene expression (IL10, IL1β, TNFα, IFNγ), telomere length, lipid peroxidation, and nitric oxide in broilers reared at high altitude.",
    "authors": [
      "Bahadoran S",
      "Vaeznia S",
      "Hassanpour H"
    ],
    "journal": "Veterinary and animal science",
    "journalAbbr": "Vet Anim Sci",
    "topic": "telomere",
    "country": "Unspecified",
    "countryCode": "--",
    "affiliation": [
      "Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran.",
      "Department of Basic Sciences, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran."
    ],
    "keywords": [
      "telomere"
    ],
    "abstract": "PubMed record in Veterinary and animal science (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42116462",
    "doi": "10.1016/j.foodres.2026.119189",
    "year": 2026,
    "title": "Dietary geroprotective peptides: structural determinants, AI-driven discovery, and synthetic biology production for healthy ageing.",
    "authors": [
      "Lee CH",
      "Nyakuma BB",
      "Zhou T",
      "Xue J",
      "Cheong TH",
      "Li Y",
      "Wong SL",
      "Gao L",
      "Wu X"
    ],
    "journal": "Food research international (Ottawa, Ont.)",
    "journalAbbr": "Food Res Int",
    "topic": "caloric",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "State Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, No. 32, Xiqi Road, Tianjin, Airport Economic Park, Tianjin 300308, China.",
      "Department of Chemical Sciences, Faculty of Science and Computing, North-Eastern University, P. M. B. 0198 Gombe, Gombe State, Nigeria."
    ],
    "keywords": [
      "mTOR",
      "longevity",
      "lifespan",
      "healthspan",
      "Bioactive Peptides, Dietary",
      "Animals"
    ],
    "abstract": "PubMed record in Food research international (Ottawa, Ont.) (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42114673",
    "doi": "10.1016/j.metabol.2026.156630",
    "year": 2026,
    "title": "Single-cell and spatial omics in liver identify cell-cell communication regulators in aging and insulin resistance.",
    "authors": [
      "Zhao W",
      "Jiao X",
      "Du K",
      "Sun Q",
      "Duan J",
      "Cao Y",
      "Shen X",
      "Said Z",
      "Karri SS",
      "Ellsworth P",
      "Hu W",
      "Sargsyan A"
    ],
    "journal": "Metabolism: clinical and experimental",
    "journalAbbr": "Metabolism",
    "topic": "singlecell",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Department of Mathematics and the NSF-Simons Center for Multiscale Cell Fate Research, University of California, Irvine, Irvine, CA, USA; Diabetes Center, University of California Irvine, Irvine, CA, USA.",
      "Diabetes Center, University of California Irvine, Irvine, CA, USA; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of California, Irvine, Irvine, CA, USA; Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA, USA."
    ],
    "keywords": [
      "single-cell RNA-seq",
      "Animals",
      "Insulin Resistance",
      "Aging",
      "Liver",
      "Cell Communication"
    ],
    "abstract": "PubMed record in Metabolism: clinical and experimental (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42109930",
    "doi": "10.1007/s11571-026-10457-9",
    "year": 2026,
    "title": "Rosmarinic acid mitigates age-related loss of EEG complexity in temporal cortex: a recurrence quantification analysis.",
    "authors": [
      "Uslu S",
      "Kantar D"
    ],
    "journal": "Cognitive neurodynamics",
    "journalAbbr": "Cogn Neurodyn",
    "topic": "senescence",
    "country": "Unspecified",
    "countryCode": "--",
    "affiliation": [
      "Faculty of Medicine, Department of Biophysics, Akdeniz University, Antalya, Turkey.",
      "Faculty of Medicine, Department of Biophysics, Bursa Uludağ University, Bursa, Turkey."
    ],
    "keywords": [
      "senescence"
    ],
    "abstract": "PubMed record in Cognitive neurodynamics (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42107763",
    "doi": "10.1016/j.yjmcc.2026.05.005",
    "year": 2026,
    "title": "Heartbeats and hidden codes: Decoding cardiac aging with multi-omics and computational approaches.",
    "authors": [
      "Liu SL",
      "Qian L"
    ],
    "journal": "Journal of molecular and cellular cardiology",
    "journalAbbr": "J Mol Cell Cardiol",
    "topic": "singlecell",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Department of Pathology and Laboratory Medicine, McAllister Heart Institute, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, United States.",
      "Department of Pathology and Laboratory Medicine, McAllister Heart Institute, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, United States. Electronic address: li_qian@med.unc.edu."
    ],
    "keywords": [
      "senescence",
      "Multiomics",
      "Aging",
      "Animals",
      "Humans",
      "Computational Biology"
    ],
    "abstract": "PubMed record in Journal of molecular and cellular cardiology (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42107722",
    "doi": "10.1016/j.arr.2026.103158",
    "year": 2026,
    "title": "Ergothioneine as a potential geroprotector: Targeting molecular hallmarks of ageing and age-related diseases.",
    "authors": [
      "Zhao P",
      "Qi Y"
    ],
    "journal": "Ageing research reviews",
    "journalAbbr": "Ageing Res Rev",
    "topic": "telomere",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang 110122, China.",
      "Department of Radiology, Shengjing Hospital of China Medical University, Shenyang, China. Electronic address: womanman1982@163.com."
    ],
    "keywords": [
      "telomere",
      "mitochondria",
      "longevity",
      "healthspan",
      "Ergothioneine",
      "Humans"
    ],
    "abstract": "PubMed record in Ageing research reviews (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42107134",
    "doi": "10.1016/j.biomaterials.2026.124249",
    "year": 2026,
    "title": "Microvascular remodeling strategy for skin rejuvenation through microenvironmental reprogramming and appendage restoration.",
    "authors": [
      "Zhou J",
      "Jiang S",
      "Wang L",
      "Dong T",
      "Yu L",
      "Li H",
      "Gao Z",
      "Wu J",
      "Lin K"
    ],
    "journal": "Biomaterials",
    "journalAbbr": "Biomaterials",
    "topic": "senescence",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Department of Oral and Cranio-Maxillofacial Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, College of Stomatology, Shanghai Jiao Tong University, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology; Shanghai Research Institute of Stomatology, Shanghai, 200011, China; Department of Stomatology, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China; Stomatological Hospital of Xiamen Medical College, Xiamen Key Laboratory of Stomatological Disease Diagnosis and Treatment, Xiamen, 361008, China.",
      "Department of Oral and Cranio-Maxillofacial Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, College of Stomatology, Shanghai Jiao Tong University, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology; Shanghai Research Institute of Stomatology, Shanghai, 200011, China; Stomatological Hospital of Xiamen Medical College, Xiamen Key Laboratory of Stomatological Disease Diagnosis and Treatment, Xiamen, 361008, China."
    ],
    "keywords": [
      "senescence",
      "reprogramming",
      "rejuvenation",
      "Animals",
      "Humans",
      "Mice"
    ],
    "abstract": "PubMed record in Biomaterials (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42105713",
    "doi": "10.1016/j.intimp.2026.116795",
    "year": 2026,
    "title": "Yakuchinone A alleviates hepatic ischemia-reperfusion injury in aging livers via the SESN2/AKT1/NRF2 pathway.",
    "authors": [
      "Ran B",
      "Li W",
      "Li Y",
      "Fu C",
      "Xie Y",
      "Li Y"
    ],
    "journal": "International immunopharmacology",
    "journalAbbr": "Int Immunopharmacol",
    "topic": "singlecell",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Department of Hepatobiliary and Pancreatic Surgery, the Second Affiliated Hospital of Hainan Medical University, Haikou, Hainan 570105, China.",
      "Department of Liver Transplantation, the Second Affiliated Hospital of Hainan Medical University, Haikou, Hainan 570105, China."
    ],
    "keywords": [
      "single-cell RNA-seq",
      "Animals",
      "NF-E2-Related Factor 2",
      "Reperfusion Injury",
      "Proto-Oncogene Proteins c-akt",
      "Sestrins"
    ],
    "abstract": "PubMed record in International immunopharmacology (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42105620",
    "doi": "10.1016/j.theriogenology.2026.117974",
    "year": 2026,
    "title": "Transcriptome and metabolome analysis reveals that cuproptosis in bovine cumulus cells triggers the intercellular transmission of senescence and mitochondrial dysfunction to impair oocyte quality.",
    "authors": [
      "Xu H",
      "Tian T",
      "Xu D",
      "Du X",
      "Su R",
      "Liang J",
      "Liu Y",
      "Zhang Y",
      "Liu C",
      "Liang S",
      "Li Q",
      "Ding D"
    ],
    "journal": "Theriogenology",
    "journalAbbr": "Theriogenology",
    "topic": "senescence",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "College of Animal Sciences, Jilin University, Changchun, 130062, Jilin, China.",
      "College of Animal Sciences, Jilin University, Changchun, 130062, Jilin, China; Prenatal Diagnosis Center, Reproductive Medicine Center, The First Hospital of Jilin University, Changchun, 130062, Jilin, China."
    ],
    "keywords": [
      "senescence",
      "DNA methylation",
      "mitochondria",
      "Animals",
      "Cattle",
      "Female"
    ],
    "abstract": "PubMed record in Theriogenology (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42070665",
    "doi": "10.1016/j.arr.2026.103156",
    "year": 2026,
    "title": "Nitric oxide redox signaling as a convergent mechanism in aging and fibrosis.",
    "authors": [
      "Guo X",
      "Cao Y",
      "Liu L",
      "Peng Y",
      "Du Y",
      "Yang F",
      "Huang D"
    ],
    "journal": "Ageing research reviews",
    "journalAbbr": "Ageing Res Rev",
    "topic": "senescence",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, China.",
      "State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, China; Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, China."
    ],
    "keywords": [
      "senescence",
      "mTOR",
      "proteostasis",
      "Humans",
      "Aging",
      "Nitric Oxide"
    ],
    "abstract": "PubMed record in Ageing research reviews (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42070623",
    "doi": "10.1016/j.envres.2026.124600",
    "year": 2026,
    "title": "Do epigenetic aging biomarkers mediate the association between exposure and health outcomes? A scoping review of mediation analysis.",
    "authors": [
      "Fujii R",
      "Tsuboi Y",
      "Cardenas A",
      "Okuzono SS",
      "Valeri L",
      "Yamada H",
      "Yamazaki M",
      "Okumiyama H",
      "Murakami K",
      "Umematsu R",
      "Suzuki K"
    ],
    "journal": "Environmental research",
    "journalAbbr": "Environ Res",
    "topic": "epigenetic",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Department of Preventive Medical Sciences, Fujita Health University School of Medical Sciences, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Japan; Department of Preventive Medicine, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, Japan. Electronic address: rfujii@fujita-hu.ac.jp.",
      "Department of Preventive Medical Sciences, Fujita Health University School of Medical Sciences, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Japan."
    ],
    "keywords": [
      "DNA methylation",
      "biomarkers",
      "Aging",
      "Humans",
      "Epigenesis, Genetic",
      "Biomarkers"
    ],
    "abstract": "PubMed record in Environmental research (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42068880",
    "doi": "10.1016/j.phymed.2026.158244",
    "year": 2026,
    "title": "Limonin mitigates hepatic senescence and fibrosis in MASH mice by targeting STAT3 to inhibit Galectin-3/mTORC1 signaling.",
    "authors": [
      "Lan T",
      "Wang W",
      "Zeng XX",
      "Mao WL",
      "Lu T",
      "Wang SW"
    ],
    "journal": "Phytomedicine : international journal of phytotherapy and phytopharmacology",
    "journalAbbr": "Phytomedicine",
    "topic": "senescence",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Department of Pharmacy, the Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People's Hospital, Quzhou 324000, China.",
      "Zhejiang Chinese Medical University Affiliated Four-provinces Marginal Hospital of Traditional Chinese Medicine, Quzhou Hospital of Traditional Chinese Medicine, Quzhou 324000, China."
    ],
    "keywords": [
      "senescence",
      "rapamycin",
      "mTOR",
      "Animals",
      "STAT3 Transcription Factor",
      "Signal Transduction"
    ],
    "abstract": "PubMed record in Phytomedicine : international journal of phytotherapy and phytopharmacology (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42059427",
    "doi": "10.1080/07853890.2026.2663263",
    "year": 2026,
    "title": "Tranexamic acid protects human dermal fibroblasts from D-galactose-induced senescence via the GPR30/MAPK pathway.",
    "authors": [
      "Lin Y",
      "Wang Y",
      "Wang W",
      "Deng Z",
      "Zhang Y",
      "Peng Y",
      "Tang J",
      "Li J",
      "Huang C",
      "Jian D"
    ],
    "journal": "Annals of medicine",
    "journalAbbr": "Ann Med",
    "topic": "senescence",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China.",
      "National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China."
    ],
    "keywords": [
      "senescence",
      "Humans",
      "Female",
      "Fibroblasts",
      "Receptors, G-Protein-Coupled",
      "Cellular Senescence"
    ],
    "abstract": "PubMed record in Annals of medicine (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42056751",
    "doi": "10.1016/j.lssr.2025.12.002",
    "year": 2026,
    "title": "Transcriptomics analyses reveal microgravity triggers estrogen synthesis amidst degeneration and aging in human ovarian granulosa cells.",
    "authors": [
      "Yin C",
      "Zhang J",
      "Cheng Z",
      "He F",
      "Lu H",
      "Zhao S"
    ],
    "journal": "Life sciences in space research",
    "journalAbbr": "Life Sci Space Res (Amst)",
    "topic": "singlecell",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, 250012, China.",
      "Jinan Foreign Language School, Jinan, Shandong, 250012, China."
    ],
    "keywords": [
      "rapamycin",
      "mitochondria",
      "Female",
      "Humans",
      "Granulosa Cells",
      "Estrogens"
    ],
    "abstract": "PubMed record in Life sciences in space research (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42036745",
    "doi": "10.9758/cpn.25.1360",
    "year": 2026,
    "title": "Cellular Senescence of Patient-derived Fibroblasts Reveals the Mid-old Stage as a Critical Window for Transcriptomic Signatures Linked to Alzheimer's Disease Biomarkers and Classification.",
    "authors": [
      "Cho YJ",
      "Yoon S",
      "Kim Y",
      "Song HM",
      "Nam YJ",
      "Lee SH",
      "Lee S",
      "Shin D",
      "Lee SM",
      "Moon SY",
      "Kim EJ",
      "Cho SH"
    ],
    "journal": "Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology",
    "journalAbbr": "Clin Psychopharmacol Neurosci",
    "topic": "senescence",
    "country": "South Korea",
    "countryCode": "KR",
    "affiliation": [
      "Department of Biomedical Sciences, Graduate School of Ajou University, Suwon, Korea.",
      "Department of Psychiatry, Ajou University School of Medicine, Suwon, Korea."
    ],
    "keywords": [
      "senescence",
      "biomarkers"
    ],
    "abstract": "PubMed record in Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42034299",
    "doi": "10.1016/j.jnutbio.2026.110390",
    "year": 2026,
    "title": "A potential anti-aging probiotic: Lactobacillus paracasei JS-3 extends lifespan in Caenorhabditis elegans and modulates the gut microbiota in the elderly.",
    "authors": [
      "Li A",
      "Li H",
      "Yang L",
      "Zhang N",
      "Wu J",
      "Wang X",
      "Tan S",
      "Li L",
      "Min R",
      "Xiao M",
      "Su S",
      "Yang M"
    ],
    "journal": "The Journal of nutritional biochemistry",
    "journalAbbr": "J Nutr Biochem",
    "topic": "nad",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "School of Chinese Meteria Medica, Beijing University of Chinese Medicine, Beijing, China.",
      "School of Chinese Meteria Medica, Beijing University of Chinese Medicine, Beijing, China. Electronic address: wxyph.d@163.com."
    ],
    "keywords": [
      "lifespan",
      "Animals",
      "Caenorhabditis elegans",
      "Probiotics",
      "Lacticaseibacillus paracasei",
      "Gastrointestinal Microbiome"
    ],
    "abstract": "PubMed record in The Journal of nutritional biochemistry (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42027317",
    "doi": "10.1016/j.rpth.2026.103458",
    "year": 2026,
    "title": "Resistance to age-related hypercoagulability: insights from the naked mole rat.",
    "authors": [
      "Regnault V",
      "Lagrange J",
      "Faulkes CG",
      "Cruickshank JK",
      "Lakomy C",
      "Benetos A",
      "Denis CV",
      "Lacolley P"
    ],
    "journal": "Research and practice in thrombosis and haemostasis",
    "journalAbbr": "Res Pract Thromb Haemost",
    "topic": "singlecell",
    "country": "United Kingdom",
    "countryCode": "UK",
    "affiliation": [
      "Université de Lorraine, INSERM, DCAC, Nancy, France.",
      "School of Biological and Chemical Sciences, Queen Mary University of London, London, United Kingdom."
    ],
    "keywords": [
      "lifespan",
      "Animals",
      "Humans",
      "Thrombophilia",
      "Aging",
      "Mole Rats"
    ],
    "abstract": "PubMed record in Research and practice in thrombosis and haemostasis (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42025598",
    "doi": "10.1016/j.bioorg.2026.109868",
    "year": 2026,
    "title": "The structure-activity relationship study of torkinib derivatives as mTOR inhibitors with senolytic and STAT3 inhibitory activities.",
    "authors": [
      "Oleksak P",
      "Rysanek D",
      "Vancurova M",
      "Novak J",
      "Maurencova D",
      "Rousarova E",
      "Capek J",
      "Rousar T",
      "Vales K",
      "Skopek V",
      "Maslowska MJ",
      "Gumauskaite K"
    ],
    "journal": "Bioorganic chemistry",
    "journalAbbr": "Bioorg Chem",
    "topic": "senescence",
    "country": "Unspecified",
    "countryCode": "--",
    "affiliation": [
      "Department of Chemistry, Faculty of Science, University of Hradec Kralove, Rokitanskeho 62, 50003 Hradec Kralove, Czech Republic.",
      "Laboratory of Genome Integrity, Institute of Molecular Genetics of the Czech Academy of Sciences, Videnska 1083, 14220 Prague 4, Czech Republic."
    ],
    "keywords": [
      "rapamycin",
      "mTOR",
      "Structure-Activity Relationship",
      "STAT3 Transcription Factor",
      "TOR Serine-Threonine Kinases",
      "Humans"
    ],
    "abstract": "PubMed record in Bioorganic chemistry (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42012979",
    "doi": "10.1016/j.celrep.2026.117265",
    "year": 2026,
    "title": "The naked mole-rat microbiome is associated with healthy aging and social structure.",
    "authors": [
      "Tanes C",
      "Wilson NG",
      "Smith M",
      "Patel TT",
      "Merenstein C",
      "Bushman FD",
      "Bittinger K",
      "Buffenstein R"
    ],
    "journal": "Cell reports",
    "journalAbbr": "Cell Rep",
    "topic": "singlecell",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA, USA.",
      "Department of Biological Sciences, University of Illinois, Chicago, IL, USA."
    ],
    "keywords": [
      "microbiome",
      "naked mole-rat",
      "longevity"
    ],
    "abstract": "PubMed record in Cell reports (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42012850",
    "doi": "10.1080/13685538.2026.2662042",
    "year": 2026,
    "title": "Testosterone deficiency in aging males: a dual threat to vascular and bone health through coronary artery calcification and osteoporosis - a narrative review.",
    "authors": [
      "Li S"
    ],
    "journal": "The aging male : the official journal of the International Society for the Study of the Aging Male",
    "journalAbbr": "Aging Male",
    "topic": "nad",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Department of Hainan Health Care in the Second Medical Center of Chinese PLA General Hospital at Haitang Bay, Sanya City, Hainan Province, People's Republic of China."
    ],
    "keywords": [
      "NAD",
      "Humans",
      "Male",
      "Osteoporosis",
      "Testosterone",
      "Coronary Artery Disease"
    ],
    "abstract": "PubMed record in The aging male : the official journal of the International Society for the Study of the Aging Male (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42006013",
    "doi": "10.1016/j.bioactmat.2026.03.060",
    "year": 2026,
    "title": "Metformin alleviates aging-associated periodontitis via NRF2-mediated restoration of the IRE1α dependent unfolded protein response.",
    "authors": [
      "Sun Y",
      "Chen Q",
      "Zhao Y",
      "Yin Y",
      "Chen Q",
      "Yang L",
      "Liu Z",
      "Chen R",
      "Xu X",
      "Song J"
    ],
    "journal": "Bioactive materials",
    "journalAbbr": "Bioact Mater",
    "topic": "senescence",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "College of Stomatology, Chongqing Medical University, Chongqing, 401147, China.",
      "Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences, Chongqing, 401147, China."
    ],
    "keywords": [
      "senescence",
      "stem cell",
      "proteostasis"
    ],
    "abstract": "PubMed record in Bioactive materials (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "42000694",
    "doi": "10.1016/j.archger.2026.106254",
    "year": 2026,
    "title": "The metabolic-inflammatory axis in aging: A multi-organ framework anchored in Sarcopenia - A review.",
    "authors": [
      "Liang T"
    ],
    "journal": "Archives of gerontology and geriatrics",
    "journalAbbr": "Arch Gerontol Geriatr",
    "topic": "caloric",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Department of Geriatrics, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, 1111 XianXia Road, Shanghai 200336, China."
    ],
    "keywords": [
      "rapamycin",
      "mTOR",
      "inflammaging",
      "mitochondria",
      "healthspan",
      "Humans"
    ],
    "abstract": "PubMed record in Archives of gerontology and geriatrics (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41967384",
    "doi": "10.1016/j.biomaterials.2026.124117",
    "year": 2026,
    "title": "Extracellular matrix-associated molecules of senescent cells induce a senescence phenotype in proliferative cells via TGF-β signaling pathway.",
    "authors": [
      "Sá Ferreira R",
      "Aires HR",
      "Rebelo C",
      "Passos JF",
      "Ori A",
      "Pitrez PR",
      "Ferreira L"
    ],
    "journal": "Biomaterials",
    "journalAbbr": "Biomaterials",
    "topic": "senescence",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "CNC- Center for Neurosciences and Cell Biology, University of Coimbra, Coimbra, Portugal; CIBB - Centre for Innovative Biomedicine and Biotechnology, University of Coimbra, Coimbra, Portugal.",
      "CIBB - Centre for Innovative Biomedicine and Biotechnology, University of Coimbra, Coimbra, Portugal."
    ],
    "keywords": [
      "senescence",
      "Humans",
      "Signal Transduction",
      "Cellular Senescence",
      "Cell Proliferation",
      "Animals"
    ],
    "abstract": "PubMed record in Biomaterials (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41962332",
    "doi": "10.1016/j.jnha.2026.100844",
    "year": 2026,
    "title": "Fatigue, muscle fatigability, and the Hallmarks of Aging: a narrative review.",
    "authors": [
      "Ronca A",
      "Bellelli F",
      "Proietti M",
      "Rolland Y",
      "Vellas B",
      "de Souto Barreto P"
    ],
    "journal": "The journal of nutrition, health & aging",
    "journalAbbr": "J Nutr Health Aging",
    "topic": "inflammaging",
    "country": "France",
    "countryCode": "FR",
    "affiliation": [
      "IHU Health Age, Toulouse, France; Division of Subacute Care, IRCCS Istituti Clinici Scientifici Maugeri, Milan, Italy. Electronic address: anna.ronca@icsmaugeri.it.",
      "IHU Health Age, Toulouse, France; Institut du Vieillissement, Gérontopole of the Centre Hospitalo-Universitaire of Toulouse, Toulouse, France."
    ],
    "keywords": [
      "autophagy",
      "proteostasis",
      "mitochondria",
      "biomarkers",
      "Humans",
      "Aging"
    ],
    "abstract": "PubMed record in The journal of nutrition, health & aging (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41953144",
    "doi": "10.1016/j.bioactmat.2026.03.036",
    "year": 2026,
    "title": "Epigenetic reprogramming periosteum promotes aging critical segmental bone defect repair via methylation remodeling.",
    "authors": [
      "Zheng J",
      "Ke J",
      "Wu S",
      "Lan Y",
      "Zhong Z",
      "Yang S",
      "Zhao N",
      "Wang Z",
      "Chai M",
      "Shi X",
      "Wang Y"
    ],
    "journal": "Bioactive materials",
    "journalAbbr": "Bioact Mater",
    "topic": "senescence",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "School of Materials Science and Engineering, South China University of Technology, Guangzhou, 510641, PR China.",
      "National Engineering Research Center for Tissue Restoration and Reconstruction, South China University of Technology, Guangzhou, 510006, PR China."
    ],
    "keywords": [
      "senescence",
      "DNA methylation",
      "reprogramming"
    ],
    "abstract": "PubMed record in Bioactive materials (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41942023",
    "doi": "10.1016/j.mce.2026.112802",
    "year": 2026,
    "title": "Concept and connotation of the geroprotective and anti-aging effects of metformin: From AMPK activation to SASP suppression.",
    "authors": [
      "Aedh AI",
      "Al-Kuraishy HM",
      "Shokr MM",
      "Alruwaili M",
      "El-Saber Batiha G"
    ],
    "journal": "Molecular and cellular endocrinology",
    "journalAbbr": "Mol Cell Endocrinol",
    "topic": "senescence",
    "country": "Unspecified",
    "countryCode": "--",
    "affiliation": [
      "Professor of internal medicine, Najran University, Saudi Arabia; Medicine and critical care consultant, Najran University Hospital, Saudi Arabia. Electronic address: Dr.abuwaleed3730@hotmail.com.",
      "Department of Clinical Pharmacology and Medicine, College of Medicine, Mustansiriyah University, Baghdad, Iraq. Electronic address: haydermutter@uomustansiriyah.edu.iq."
    ],
    "keywords": [
      "senescence",
      "rapamycin",
      "mTOR",
      "autophagy",
      "mitochondria",
      "Metformin"
    ],
    "abstract": "PubMed record in Molecular and cellular endocrinology (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41935903",
    "doi": "10.1016/j.scib.2026.03.017",
    "year": 2026,
    "title": "The naked mole-rat cGAS promotes homologous recombination repair and delays aging.",
    "authors": [
      "Du C",
      "Xie Y",
      "Ding H",
      "E T",
      "Li L",
      "Liu X"
    ],
    "journal": "Science bulletin",
    "journalAbbr": "Sci Bull (Beijing)",
    "topic": "singlecell",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Institute of Development and Regeneration, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangdong-Hong Kong Joint Laboratory for Stem Cell and Regenerative Medicine, GIBH-CUHK Joint Research Laboratory on Stem Cell and Regenerative Medicine, GIBH-HKU Guangdong-Hong Kong Stem Cell and Regenerative Medicine Research Centre, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China; School of Life Sciences, University of Science and Technology of China, Hefei 230027, China.",
      "GMU-GIBH Joint School of Life Sciences, State Key Lab of Respiratory Disease, The Guangdong-Hong Kong-Macao Joint Laboratory for Cell Fate Regulation and Diseases, Guangzhou Medical University, Guangzhou 511436, China."
    ],
    "keywords": [
      "naked mole-rat"
    ],
    "abstract": "PubMed record in Science bulletin (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41932624",
    "doi": "10.1016/j.jnutbio.2026.110362",
    "year": 2026,
    "title": "Mapping the genetically predicted associations of plasma metabolites with sarcopenia and aging traits: Evidence from bidirectional Mendelian randomization and transcriptome analysis.",
    "authors": [
      "Wang Q",
      "Lu S"
    ],
    "journal": "The Journal of nutritional biochemistry",
    "journalAbbr": "J Nutr Biochem",
    "topic": "singlecell",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Department of Orthopedics & Elderly Spinal Surgery, National Clinical Research Center for Geriatric Diseases, Xuanwu Hospital of Capital Medical University, Beijing, China; Laboratory for Clinical Medicine, Capital Medical University, Beijing, China.",
      "Department of Orthopedics & Elderly Spinal Surgery, National Clinical Research Center for Geriatric Diseases, Xuanwu Hospital of Capital Medical University, Beijing, China; Laboratory for Clinical Medicine, Capital Medical University, Beijing, China. Electronic address: spinelu@xwhosp.org."
    ],
    "keywords": [
      "telomere",
      "NAD",
      "Humans",
      "Sarcopenia",
      "Male",
      "Aging"
    ],
    "abstract": "PubMed record in The Journal of nutritional biochemistry (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41919394",
    "doi": "10.1080/07853890.2026.2627667",
    "year": 2026,
    "title": "Research progress of mesenchymal stem cells/stromal cells and their derivatives against cell senescence in the treatment of osteoarthritis.",
    "authors": [
      "Deng D",
      "Wu Y",
      "Wu T",
      "Huang D",
      "Liang X",
      "Tan C",
      "Li Y",
      "Liu Y"
    ],
    "journal": "Annals of medicine",
    "journalAbbr": "Ann Med",
    "topic": "senescence",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Department of Rheumatology and Immunology, Laboratory of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, China.",
      "Department of Rheumatology, Mianyang Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Mianyang, China."
    ],
    "keywords": [
      "senescence",
      "stem cell",
      "mitochondria",
      "Humans",
      "Cellular Senescence",
      "Osteoarthritis"
    ],
    "abstract": "PubMed record in Annals of medicine (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41833148",
    "doi": "10.1016/j.tice.2026.103473",
    "year": 2026,
    "title": "Mechanistic insights into aging and longevity: Implications for ovarian function and health.",
    "authors": [
      "Harrath AH"
    ],
    "journal": "Tissue & cell",
    "journalAbbr": "Tissue Cell",
    "topic": "caloric",
    "country": "Unspecified",
    "countryCode": "--",
    "affiliation": [
      "Department of Zoology, College of Science, King Saud University, Riyadh 11451, Saudi Arabia. Electronic address: hharrath@ksu.edu.sa."
    ],
    "keywords": [
      "rapamycin",
      "mTOR",
      "telomere",
      "sirtuins",
      "autophagy",
      "mitochondria"
    ],
    "abstract": "PubMed record in Tissue & cell (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41812700",
    "doi": "10.1016/j.mad.2026.112174",
    "year": 2026,
    "title": "NAD⁺ as a central metabolic hub Regulating the hallmarks of aging: Mechanisms and therapeutic implications.",
    "authors": [
      "Pei Z",
      "Liang F",
      "Wang X",
      "Li H"
    ],
    "journal": "Mechanisms of ageing and development",
    "journalAbbr": "Mech Ageing Dev",
    "topic": "senescence",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Institute of Traditional Chinese Medicine Health Industry, China Academy of Chinese Medical Sciences, Nanchang 330000, China.",
      "Department of Pharmacy, Tianjin Medical University General Hospital Airport Site, Tianjin, China."
    ],
    "keywords": [
      "senescence",
      "NAD",
      "mitochondria",
      "healthspan",
      "Humans",
      "Aging"
    ],
    "abstract": "PubMed record in Mechanisms of ageing and development (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41778393",
    "doi": "10.1080/15592294.2026.2632400",
    "year": 2026,
    "title": "Associations of breast DNA methylation-based measures of biological ageing with obesity-related breast cancer risk markers.",
    "authors": [
      "Singh A",
      "McElroy JP",
      "Weng DY",
      "Reisinger SA",
      "Freudenheim JL",
      "Shields PG",
      "Song MA"
    ],
    "journal": "Epigenetics",
    "journalAbbr": "Epigenetics",
    "topic": "telomere",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA.",
      "Department of Biomedical Informatics, Biomedical Informatics Shared Resources (BISR), The Ohio State University, Columbus, OH, USA."
    ],
    "keywords": [
      "telomere",
      "DNA methylation",
      "Humans",
      "Female",
      "DNA Methylation",
      "Breast Neoplasms"
    ],
    "abstract": "PubMed record in Epigenetics (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41747292",
    "doi": "10.18632/aging.206356",
    "year": 2026,
    "title": "A decline in glycolytic ATP production is the fundamental mechanism limiting lifespan; species with an optimal rate of decline over time survived.",
    "authors": [
      "Taguchi A",
      "Okinaka Y",
      "Claussen C",
      "Gul S"
    ],
    "journal": "Aging",
    "journalAbbr": "Aging (Albany NY)",
    "topic": "singlecell",
    "country": "Germany",
    "countryCode": "DE",
    "affiliation": [
      "Department of Regenerative Medicine Research, Foundation for Biomedical Research and Innovation at Kobe, Hyogo 650-0047, Japan.",
      "Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Discovery Research ScreeningPort, Hamburg 22525, Germany."
    ],
    "keywords": [
      "mitochondria",
      "lifespan",
      "rejuvenation"
    ],
    "abstract": "PubMed record in Aging (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41723572",
    "doi": "10.1080/19490976.2026.2630475",
    "year": 2026,
    "title": "Aging-caused the changes of the gut microbiota drive intestinal barrier dysfunction and increase sepsis susceptibility.",
    "authors": [
      "Liang H",
      "Ding X",
      "Liu S",
      "Tong S",
      "Wang X",
      "Zhang Z",
      "Wang W",
      "Zhang X",
      "Yuan Y",
      "Jiang Y",
      "Sun T"
    ],
    "journal": "Gut microbes",
    "journalAbbr": "Gut Microbes",
    "topic": "inflammaging",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Department of Critical Care Medicine, Department of Emergency Medicine, The First Affiliated Hospital of Zhengzhou University, Henan Engineering Research Center for Critical Care Medicine, Henan Key Laboratory of Critical Care Medicine, Henan Key Laboratory of Sepsis in Health Commission, Zhengzhou Key Laboratory of Sepsis, Henan Sepsis Diagnosis and Treatment Center, Zhengzhou, People's Republic of China.",
      "Department of Pediatrics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China."
    ],
    "keywords": [
      "autophagy",
      "Animals",
      "Sepsis",
      "Intestinal Barrier Function",
      "Gastrointestinal Microbiome",
      "Humans"
    ],
    "abstract": "PubMed record in Gut microbes (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41674011",
    "doi": "10.1080/0886022X.2026.2628471",
    "year": 2026,
    "title": "LncRNA Gm44981 modulates EZH2-H3K27me3-p21 axis to suppress mesangial cell senescence and kidney aging.",
    "authors": [
      "Li J",
      "Wei L",
      "Gao F",
      "Zeng L",
      "Jiang H",
      "Chen L"
    ],
    "journal": "Renal failure",
    "journalAbbr": "Ren Fail",
    "topic": "senescence",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Dialysis Department of Nephrology Hospital, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.",
      "Department of Nephrology, People's Hospital of Zhengzhou University, He'nan Provincial People's Hospital, He'nan Provincial Key Laboratory of Kidney Disease and Immunology, Zhengzhou, China."
    ],
    "keywords": [
      "senescence",
      "Animals",
      "RNA, Long Noncoding",
      "Enhancer of Zeste Homolog 2 Protein",
      "Cellular Senescence",
      "Mesangial Cells"
    ],
    "abstract": "PubMed record in Renal failure (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41636765",
    "doi": "10.1177/1096620X261421080",
    "year": 2026,
    "title": "Stimulatory Effects of (+)-Epicatechin on Mitochondrial Biogenesis and Function in Skeletal Muscle of Aged Rats: Underlying Mechanisms.",
    "authors": [
      "Ramirez-Sanchez I",
      "Ordoñez-Razo R",
      "Najera V",
      "Ceballos G",
      "Villarreal F"
    ],
    "journal": "Journal of medicinal food",
    "journalAbbr": "J Med Food",
    "topic": "nad",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Seccion de Estudios de Posgrado e Investigacion, Escuela Superior de Medicina, IPN, Mexico City, México.",
      "Unidad de Investigacion Medica en Genetica Humana, Hospital De Pediatria, Centro Médico Nacional Siglo XXI, Ciudad de Mexico, México."
    ],
    "keywords": [
      "NAD",
      "mitochondria",
      "Animals",
      "Catechin",
      "Male",
      "Muscle, Skeletal"
    ],
    "abstract": "PubMed record in Journal of medicinal food (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41635976",
    "doi": "10.1080/07853890.2026.2624183",
    "year": 2026,
    "title": "Testicular ageing as a central hallmark of male senescence: characteristics, molecular mechanisms and emerging therapeutic strategies.",
    "authors": [
      "Gao J",
      "Wang L",
      "Li W",
      "Liu W"
    ],
    "journal": "Annals of medicine",
    "journalAbbr": "Ann Med",
    "topic": "senescence",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital, Changsha, China.",
      "Hunan Provincial University Key Laboratory of the Fundamental and Clinical Research on Functional Nucleic Acid, Changsha Medical University, Changsha, China."
    ],
    "keywords": [
      "senescence",
      "Male",
      "Humans",
      "Aging",
      "Testis",
      "Spermatogenesis"
    ],
    "abstract": "PubMed record in Annals of medicine (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41536554",
    "doi": "10.1016/j.jor.2025.11.045",
    "year": 2026,
    "title": "Unveiling CDKN1A and RELA: Machine learning-driven aging biomarkers for precision diagnosis and therapy in knee osteoarthritis.",
    "authors": [
      "Hu Z",
      "Xu Z",
      "Xiao T",
      "Huang Q",
      "Wu Z"
    ],
    "journal": "Journal of orthopaedics",
    "journalAbbr": "J Orthop",
    "topic": "singlecell",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Shantou Hospital of Traditional Chinese Medicine, Guangzhou University of Traditional Chinese Medicine, Shantou, 515000, China.",
      "Guangzhou University of Traditional Chinese Medicine, Guangzhou, 510000, China."
    ],
    "keywords": [
      "senescence",
      "biomarkers"
    ],
    "abstract": "PubMed record in Journal of orthopaedics (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41510997",
    "doi": "10.1080/21623945.2025.2611481",
    "year": 2026,
    "title": "Lack of receptor for advanced glycation end products attenuates obesity-induced adipose tissue senescence in mice.",
    "authors": [
      "Du Z",
      "Wu J",
      "Zhang T",
      "Ma X",
      "Li Z",
      "Xu J",
      "You J",
      "Chen N",
      "Wu J"
    ],
    "journal": "Adipocyte",
    "journalAbbr": "Adipocyte",
    "topic": "senescence",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Department of Pharmacy, The Second People's Hospital of Yibin, Yibin, China.",
      "Basic Medicine Research Innovation Center for Cardiometabolic Diseases，Ministry of Education, Laboratory for Cardiovascular Pharmacology, Department of Pharmacology, School of Pharmacy, Luzhou Municipal Key Laboratory of Thrombosis and Vascular Biology Southwest Medical University, Luzhou, China."
    ],
    "keywords": [
      "senescence",
      "Animals",
      "Receptor for Advanced Glycation End Products",
      "Adipose Tissue",
      "Mice",
      "Obesity"
    ],
    "abstract": "PubMed record in Adipocyte (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41490578",
    "doi": "10.1016/j.arr.2026.103009",
    "year": 2026,
    "title": "The epigenetic rejuvenation promise: Partial reprogramming as a therapeutic strategy for aging and disease.",
    "authors": [
      "Li YY",
      "Tay FR"
    ],
    "journal": "Ageing research reviews",
    "journalAbbr": "Ageing Res Rev",
    "topic": "stemcell",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "State Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi International Joint Research Center for Oral Diseases, School of Stomatology, The Fourth Military Medical University, Xi'an, Shaanxi 710032, China; Department of General Dentistry, Xiamen University Affiliated Chenggong Hospital, The 73rd Army Hospital of Chinese PLA, Xiamen, Fujian 361001, China. Electronic address: yuanyuanli1@fmmu.edu.cn.",
      "Dental College of Georgia, Augusta University, Augusta, GA 30912, USA. Electronic address: ftay@augusta.edu."
    ],
    "keywords": [
      "stem cell",
      "reprogramming",
      "rejuvenation",
      "Humans",
      "Kruppel-Like Factor 4",
      "Rejuvenation"
    ],
    "abstract": "PubMed record in Ageing research reviews (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41468690",
    "doi": "10.2460/ajvr.25.09.0343",
    "year": 2026,
    "title": "Senescence-associated gene pathways are differentially expressed in equine aging-related osteoarthritis.",
    "authors": [
      "Singer J",
      "Chow L",
      "Ammons D",
      "Sabino I",
      "Impastato R",
      "Dow S",
      "Pezzanite LM"
    ],
    "journal": "American journal of veterinary research",
    "journalAbbr": "Am J Vet Res",
    "topic": "singlecell",
    "country": "Unspecified",
    "countryCode": "--",
    "affiliation": [
      "Orthopaedic Research Center, Translational Medicine Institute, Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO.",
      "Immunotherapy Research Laboratory, Translational Medicine Institute, Department of Clinical Science, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO."
    ],
    "keywords": [
      "senescence",
      "Animals",
      "Horses",
      "Osteoarthritis",
      "Horse Diseases",
      "Aging"
    ],
    "abstract": "PubMed record in American journal of veterinary research (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41468122",
    "doi": "10.1177/08892229251411059",
    "year": 2026,
    "title": "Epigenetic Age Acceleration and Frailty Among People with HIV.",
    "authors": [
      "Oursler KK",
      "Sun YV",
      "Lozano AJ",
      "Xu K",
      "So-Armah KA",
      "Montano M",
      "Justice AC",
      "Marconi VC"
    ],
    "journal": "AIDS research and human retroviruses",
    "journalAbbr": "AIDS Res Hum Retroviruses",
    "topic": "epigenetic",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Department of Medicine, Virginia Tech Carilion School of Medicine, Roanoke, Virginia, USA.",
      "Salem VA Healthcare System, Roanoke, Virginia, USA."
    ],
    "keywords": [
      "epigenetic clock",
      "DNA methylation",
      "Humans",
      "HIV Infections",
      "Frailty",
      "Male"
    ],
    "abstract": "PubMed record in AIDS research and human retroviruses (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41454672",
    "doi": "10.1080/19490976.2025.2607076",
    "year": 2026,
    "title": "The role of gut microbiome in aging-associated diseases: where do we stand now and how technology will transform the future.",
    "authors": [
      "Aldriwesh MG",
      "Alotibi RS",
      "Alqurainy N",
      "Alrabiah S",
      "Arafah AM",
      "Alghoribi MF",
      "Ajina R"
    ],
    "journal": "Gut microbes",
    "journalAbbr": "Gut Microbes",
    "topic": "inflammaging",
    "country": "Unspecified",
    "countryCode": "--",
    "affiliation": [
      "Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.",
      "Infectious Disease Research Department, King Abdullah International Medical Research Center, Riyadh, Saudi Arabia."
    ],
    "keywords": [
      "microbiome",
      "healthspan",
      "Humans",
      "Gastrointestinal Microbiome",
      "Aging",
      "Dysbiosis"
    ],
    "abstract": "PubMed record in Gut microbes (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41453296",
    "doi": "10.1016/j.archger.2025.106123",
    "year": 2026,
    "title": "Inhibition of c-Jun/Bak signaling alleviates endothelial cell senescence and inflammation caused by mitochondrial dysfunction in DMED.",
    "authors": [
      "Jianxiong M",
      "Yingxue G",
      "Zeng Z",
      "Li Y",
      "Jie H",
      "Qiang H"
    ],
    "journal": "Archives of gerontology and geriatrics",
    "journalAbbr": "Arch Gerontol Geriatr",
    "topic": "singlecell",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Department of Nephrology, the First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Hangzhou, Zhejiang, 310000, China; Zhejiang Key Laboratory of Research and Translation for Kidney Deficiency-Stasis-Turbidity Disease, Hangzhou, Zhejiang, 310000, China.",
      "The Second Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310000, China."
    ],
    "keywords": [
      "senescence",
      "mitochondria",
      "Animals",
      "Male",
      "Cellular Senescence",
      "Rats"
    ],
    "abstract": "PubMed record in Archives of gerontology and geriatrics (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41452464",
    "doi": "10.1007/s00239-025-10296-y",
    "year": 2026,
    "title": "An Evolutionary Metric for Estimating PhyloAges from Bulk Sequencing of Hematopoietic Stem Cells Reveals the Tempo of Blood Aging in Cancer and Longevity.",
    "authors": [
      "Craig JM",
      "Tobin RM",
      "Wolfsberger W",
      "Oleksyk TK",
      "Miura S",
      "Gerhard GS",
      "Kumar S"
    ],
    "journal": "Journal of molecular evolution",
    "journalAbbr": "J Mol Evol",
    "topic": "singlecell",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Institute for Genomics and Evolutionary Medicine, Temple University, Philadelphia, PA, USA.",
      "Department of Biology, Temple University, Philadelphia, PA, USA."
    ],
    "keywords": [
      "stem cell",
      "longevity",
      "Humans",
      "Hematopoietic Stem Cells",
      "Longevity",
      "Phylogeny"
    ],
    "abstract": "PubMed record in Journal of molecular evolution (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41443306",
    "doi": "10.1016/j.jad.2025.120962",
    "year": 2026,
    "title": "Mental health across the lifecourse as predictors of epigenetic aging from a longitudinal birth cohort in the United States.",
    "authors": [
      "Jones-Antwi RE",
      "Clausing ES",
      "Shelton RC",
      "Conneely KN",
      "Prada-Ortega D",
      "Factor-Litvak P",
      "Cirrillo P",
      "Baccarelli A",
      "Cohn B",
      "Keyes KM",
      "Link BG",
      "Suglia SF"
    ],
    "journal": "Journal of affective disorders",
    "journalAbbr": "J Affect Disord",
    "topic": "epigenetic",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Department of Epidemiology, Rollins School of Public Health, Emory University, United States; Department of Public Health, Baylor University, United States. Electronic address: Rebecca_jones-antwi@baylor.edu.",
      "School of Global Integrative Studies, University of Nebraska-Lincoln, United States; Center for Brain, Biology, and Behavior, University of Nebraska-Lincoln, United States."
    ],
    "keywords": [
      "epigenetic clock",
      "DNA methylation",
      "Humans",
      "Female",
      "Male",
      "Longitudinal Studies"
    ],
    "abstract": "PubMed record in Journal of affective disorders (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41443115",
    "doi": "10.1016/j.tice.2025.103290",
    "year": 2026,
    "title": "Boosting muscle health in aging rats: The synergistic effect of vitamin C, silymarin, and endurance swimming on a high-fat diet.",
    "authors": [
      "Aghaei F",
      "Arabzadeh E",
      "Feizolahi F",
      "Nejati Bezdi A",
      "Abasi M",
      "Zargani M"
    ],
    "journal": "Tissue & cell",
    "journalAbbr": "Tissue Cell",
    "topic": "caloric",
    "country": "Unspecified",
    "countryCode": "--",
    "affiliation": [
      "Department of Exercise Physiology, Ka. C., Islamic Azad University, Karaj, Iran.",
      "Exercise Physiology Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran."
    ],
    "keywords": [
      "mTOR",
      "Animals",
      "Diet, High-Fat",
      "Swimming",
      "Ascorbic Acid",
      "Male"
    ],
    "abstract": "PubMed record in Tissue & cell (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41437892",
    "doi": "10.1002/oby.70119",
    "year": 2026,
    "title": "Senescent Mesenchymal Stromal Cells Differentially Alter Adipogenesis in Adipose Tissue, Skeletal Muscle, and Bone Marrow.",
    "authors": [
      "Zhang X",
      "Doolittle ML",
      "Fan T",
      "Tripathi U",
      "Ng YE",
      "Jiang X",
      "Passos JF",
      "Jurk D",
      "Monroe DG",
      "Tchkonia T",
      "Kirkland JL",
      "Robbins PD"
    ],
    "journal": "Obesity (Silver Spring, Md.)",
    "journalAbbr": "Obesity (Silver Spring)",
    "topic": "singlecell",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, Minnesota, USA.",
      "Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, USA."
    ],
    "keywords": [
      "senescence",
      "Mesenchymal Stem Cells",
      "Adipogenesis",
      "Animals",
      "Muscle, Skeletal",
      "Adipose Tissue"
    ],
    "abstract": "PubMed record in Obesity (Silver Spring, Md.) (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41423065",
    "doi": "10.1016/j.tcm.2025.12.004",
    "year": 2026,
    "title": "The Yin and Yang of cellular senescence in ischemia-induced myocardial injury.",
    "authors": [
      "Wolff von Gudenberg R",
      "Iske J",
      "Roeschl T",
      "Stawowy P",
      "Kirkland JL",
      "Ruhparwar A",
      "Tullius SG"
    ],
    "journal": "Trends in cardiovascular medicine",
    "journalAbbr": "Trends Cardiovasc Med",
    "topic": "senescence",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Division of Transplant Surgery, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA; Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Carl-Neuberg Straße 1, 30625 Hannover, Germany.",
      "Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum der Charité (DHZC), Augustenburger Platz 1, 13353 Berlin, Germany; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, Charitéplatz 1, 10117 Berlin, Germany."
    ],
    "keywords": [
      "senescence",
      "Humans",
      "Cellular Senescence",
      "Animals",
      "Myocardial Reperfusion Injury",
      "Fibrosis"
    ],
    "abstract": "PubMed record in Trends in cardiovascular medicine (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41330857",
    "doi": "10.1016/j.molmed.2025.11.002",
    "year": 2026,
    "title": "Neuroendocrine timekeepers: changes in normal and premature aging.",
    "authors": [
      "Petrică M",
      "Ferreira-Marques M",
      "Ribeiro RFN",
      "Cavadas C"
    ],
    "journal": "Trends in molecular medicine",
    "journalAbbr": "Trends Mol Med",
    "topic": "caloric",
    "country": "Unspecified",
    "countryCode": "--",
    "affiliation": [
      "CNC-UC - Centre for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal; CIBB - Centre for Innovation in Biomedicine and Biotechnology, University of Coimbra, Coimbra, Portugal; FMUC - Faculty of Medicine, University of Coimbra, Coimbra, Portugal.",
      "CNC-UC - Centre for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal; CIBB - Centre for Innovation in Biomedicine and Biotechnology, University of Coimbra, Coimbra, Portugal; FFUC - Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal."
    ],
    "keywords": [
      "caloric restriction",
      "Humans",
      "Aging, Premature",
      "Animals",
      "Circadian Rhythm",
      "Neurosecretory Systems"
    ],
    "abstract": "PubMed record in Trends in molecular medicine (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41319492",
    "doi": "10.1016/j.archger.2025.106088",
    "year": 2026,
    "title": "Single-cell transcriptomic analysis reveals the molecular alterations of endothelial cells during ageing.",
    "authors": [
      "Sun Y",
      "Dai Y",
      "Yin Y"
    ],
    "journal": "Archives of gerontology and geriatrics",
    "journalAbbr": "Arch Gerontol Geriatr",
    "topic": "singlecell",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Institute of Medicine, Jishou University, Jishou, Hunan 416000, China.",
      "Institute of Medicine, Jishou University, Jishou, Hunan 416000, China. Electronic address: yinyh@jsu.edu.cn."
    ],
    "keywords": [
      "Aging",
      "Endothelial Cells",
      "Gene Expression Profiling",
      "Single-Cell Analysis",
      "Transcriptome",
      "Humans"
    ],
    "abstract": "PubMed record in Archives of gerontology and geriatrics (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41318012",
    "doi": "10.1016/j.cpcardiol.2025.103233",
    "year": 2026,
    "title": "Mechanisms and targets of vascular natural aging from a systems biology perspective.",
    "authors": [
      "Ma X",
      "Zhou S",
      "Zhu Q"
    ],
    "journal": "Current problems in cardiology",
    "journalAbbr": "Curr Probl Cardiol",
    "topic": "singlecell",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Department of Anesthesiology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.",
      "Department of Cardiovascular Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China."
    ],
    "keywords": [
      "Humans",
      "Aging",
      "Systems Biology",
      "Protein Interaction Maps",
      "Signal Transduction",
      "Gene Expression Profiling"
    ],
    "abstract": "PubMed record in Current problems in cardiology (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41297544",
    "doi": "10.1016/j.cmet.2025.10.016",
    "year": 2026,
    "title": "A metabolic atlas of mouse aging.",
    "authors": [
      "Pilley SE",
      "Awad D",
      "Latumalea D",
      "New C",
      "Esparza E",
      "Wang S",
      "Shi X",
      "Zhang L",
      "Unfried M",
      "Lee JH",
      "Schmid E",
      "Mohanty I"
    ],
    "journal": "Cell metabolism",
    "journalAbbr": "Cell Metab",
    "topic": "mito",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Department of Immunology and Immune Therapeutics, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.",
      "Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA."
    ],
    "keywords": [
      "lifespan",
      "Animals",
      "Aging",
      "Mice",
      "Female",
      "Male"
    ],
    "abstract": "PubMed record in Cell metabolism (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41178687",
    "doi": "10.1177/00220345251382572",
    "year": 2026,
    "title": "CD300lf Regulates Neutrophil Aging and Periodontal Immune Homeostasis.",
    "authors": [
      "Zou Z",
      "Guo J",
      "Li J",
      "Bao Y",
      "Xie W",
      "Hu Q",
      "Wen L",
      "Lu H",
      "Liu X",
      "Dong Q",
      "Fang J",
      "Hu Q"
    ],
    "journal": "Journal of dental research",
    "journalAbbr": "J Dent Res",
    "topic": "senescence",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Hospital of Stomatology, Guanghua School of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-Sen University, Guangzhou, China.",
      "Department of Stomatology, Third Xiangya Hospital, Central South University, Changsha, China."
    ],
    "keywords": [
      "senescence",
      "Neutrophils",
      "Animals",
      "Homeostasis",
      "Mice",
      "Humans"
    ],
    "abstract": "PubMed record in Journal of dental research (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41145651",
    "doi": "10.1038/s41386-025-02237-6",
    "year": 2026,
    "title": "Hyper-maturity and accelerated aging in the hippocampus of mouse models of neuropsychiatric disorders with anxiety-like behavior.",
    "authors": [
      "Hagihara H",
      "Koshimizu H",
      "Hattori S",
      "Shoji H",
      "Tanaka M",
      "Ikeda K",
      "Miyakawa T"
    ],
    "journal": "Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology",
    "journalAbbr": "Neuropsychopharmacology",
    "topic": "singlecell",
    "country": "Japan",
    "countryCode": "JP",
    "affiliation": [
      "Division of Systems Medical Science, Center for Medical Science, Fujita Health University, Toyoake, Aichi, Japan. h-hagi@fujita-hu.ac.jp.",
      "Division of Systems Medical Science, Center for Medical Science, Fujita Health University, Toyoake, Aichi, Japan."
    ],
    "keywords": [
      "senescence",
      "single-cell RNA-seq",
      "Animals",
      "Hippocampus",
      "Disease Models, Animal",
      "Mice"
    ],
    "abstract": "PubMed record in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41130360",
    "doi": "10.1016/j.jare.2025.10.023",
    "year": 2026,
    "title": "The brain-joint axis: links between osteoarthritis and neurodegenerative disorders in aging.",
    "authors": [
      "Rabie MA",
      "Madry H",
      "Cucchiarini M",
      "El-Sayed NS"
    ],
    "journal": "Journal of advanced research",
    "journalAbbr": "J Adv Res",
    "topic": "senescence",
    "country": "Germany",
    "countryCode": "DE",
    "affiliation": [
      "Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, Egypt; Center of Experimental Orthopaedics, Saarland University and Saarland University Medical Center, Homburg/Saar, Germany. Electronic address: Mostafa.mohammed@pharma.cu.edu.eg.",
      "Center of Experimental Orthopaedics, Saarland University and Saarland University Medical Center, Homburg/Saar, Germany. Electronic address: Henning.Madry@uks.eu."
    ],
    "keywords": [
      "senescence",
      "mitochondria",
      "Humans",
      "Osteoarthritis",
      "Neurodegenerative Diseases",
      "Aging"
    ],
    "abstract": "PubMed record in Journal of advanced research (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "40957604",
    "doi": "10.1055/a-2702-4789",
    "year": 2026,
    "title": "Exercise-Induced Epigenetic Modifications: Implications for Healthy Aging.",
    "authors": [
      "Yang Q",
      "Hu Y",
      "Zhang B",
      "Hong W"
    ],
    "journal": "International journal of sports medicine",
    "journalAbbr": "Int J Sports Med",
    "topic": "epigenetic",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "School of Physical Education and Sports Training, Hunan Sports Vocational College, Changsha, China.",
      "College of Education and Liberal Arts, Adamson University, Manila, Philippines."
    ],
    "keywords": [
      "DNA methylation",
      "Humans",
      "Epigenesis, Genetic",
      "DNA Methylation",
      "Exercise",
      "Healthy Aging"
    ],
    "abstract": "PubMed record in International journal of sports medicine (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "40817725",
    "doi": "10.4103/NRR.NRR-D-25-00161",
    "year": 2026,
    "title": "Proteostasis decline and endoplasmic reticulum stress in aging: Implications for cellular senescence and senescence-associated secretory phenotype regulation.",
    "authors": [
      "Pihán P",
      "Ellerby LM",
      "Hetz C"
    ],
    "journal": "Neural regeneration research",
    "journalAbbr": "Neural Regen Res",
    "topic": "senescence",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Buck Institute for Research on Aging, Novato, CA, USA."
    ],
    "keywords": [
      "senescence",
      "proteostasis"
    ],
    "abstract": "PubMed record in Neural regeneration research (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "40751793",
    "doi": "10.1007/s11357-025-01786-4",
    "year": 2026,
    "title": "Treatment of age-related decreases in GTP levels restores endocytosis and autophagy.",
    "authors": [
      "Santana RA",
      "McWhirt JM",
      "Brewer GJ"
    ],
    "journal": "GeroScience",
    "journalAbbr": "Geroscience",
    "topic": "caloric",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Department of Biomedical Engineering, University of California Irvine, Irvine, CA, 92697, USA.",
      "Department of Biomedical Engineering, University of California Irvine, Irvine, CA, 92697, USA. GJBrewer@uci.edu."
    ],
    "keywords": [
      "rapamycin",
      "NAD",
      "autophagy",
      "proteostasis",
      "mitochondria",
      "Animals"
    ],
    "abstract": "PubMed record in GeroScience (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "40516773",
    "doi": "10.1016/j.hrthm.2025.06.005",
    "year": 2026,
    "title": "The senescent heart and atrial fibrillation.",
    "authors": [
      "Pandey AC",
      "Bidaoui G",
      "Younes H",
      "Tsakiris E",
      "Marrouche NF"
    ],
    "journal": "Heart rhythm",
    "journalAbbr": "Heart Rhythm",
    "topic": "senescence",
    "country": "Unspecified",
    "countryCode": "--",
    "affiliation": [
      "Department of Cardiology, Heart and Vascular Institute, Tulane University School of Medicine, New Orleans, Louisiana; Southeast Louisiana Veterans Health Care System, New Orleans, Louisiana.",
      "Department of Cardiology, Heart and Vascular Institute, Tulane University School of Medicine, New Orleans, Louisiana."
    ],
    "keywords": [
      "senescence",
      "mitochondria",
      "Humans",
      "Atrial Fibrillation",
      "Aging",
      "Cellular Senescence"
    ],
    "abstract": "PubMed record in Heart rhythm (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "39977444",
    "doi": "10.1113/JP287387",
    "year": 2026,
    "title": "The role of cellular senescence in endothelial dysfunction and vascular remodelling in arteriovenous fistula maturation.",
    "authors": [
      "González I",
      "Maldonado-Agurto R"
    ],
    "journal": "The Journal of physiology",
    "journalAbbr": "J Physiol",
    "topic": "senescence",
    "country": "Unspecified",
    "countryCode": "--",
    "affiliation": [
      "Center for Biomedical Research (CIBMED), Faculty of Medicine, Universidad Finis Terrae, Santiago, Chile."
    ],
    "keywords": [
      "senescence",
      "Humans",
      "Vascular Remodeling",
      "Cellular Senescence",
      "Animals",
      "Endothelium, Vascular"
    ],
    "abstract": "PubMed record in The Journal of physiology (2026). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41066590",
    "doi": "10.1126/science.aeb6125",
    "year": 2025,
    "title": "Longevity steps on the cGAS.",
    "authors": [
      "Martinez JC",
      "Seluanov A",
      "Gorbunova V"
    ],
    "journal": "Science (New York, N.Y.)",
    "journalAbbr": "Science",
    "topic": "singlecell",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Department of Biology, University of Rochester, Rochester, NY, USA.",
      "University of Rochester Medical Center, Rochester, NY, USA."
    ],
    "keywords": [
      "naked mole-rat",
      "longevity",
      "Longevity",
      "Animals",
      "DNA Repair",
      "Nucleotidyltransferases"
    ],
    "abstract": "PubMed record in Science (New York, N.Y.) (2025). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "41066557",
    "doi": "10.1126/science.adp5056",
    "year": 2025,
    "title": "A cGAS-mediated mechanism in naked mole-rats potentiates DNA repair and delays aging.",
    "authors": [
      "Chen Y",
      "Chen Z",
      "Wang H",
      "Cui Z",
      "Li KL",
      "Song Z",
      "Chen L",
      "Sun X",
      "Xu X",
      "Zhang Y",
      "Tan L",
      "Yuan J"
    ],
    "journal": "Science (New York, N.Y.)",
    "journalAbbr": "Science",
    "topic": "singlecell",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Shanghai Key Laboratory of Maternal Fetal Medicine, Clinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai, China.",
      "Key Laboratory of Medical Epigenetics and Metabolism, Institutes of Biomedical Sciences, Fudan University, Shanghai, China."
    ],
    "keywords": [
      "naked mole-rat",
      "longevity",
      "Animals",
      "Nucleotidyltransferases",
      "Mole Rats",
      "Humans"
    ],
    "abstract": "PubMed record in Science (New York, N.Y.) (2025). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "40828005",
    "doi": "10.1097/HTR.0000000000001096",
    "year": 2025,
    "title": "Traumatic Brain Injury and Accelerated Epigenetic Aging Among Post-9/11 Veterans.",
    "authors": [
      "Bourassa KJ",
      "Martindale SL",
      "Garrett ME",
      "Ashley-Koch AE",
      "Beckham JC",
      "Kimbrel NA",
      "Rowland JA",
      "VA Mid-Atlantic Mirecc Workgroup"
    ],
    "journal": "The Journal of head trauma rehabilitation",
    "journalAbbr": "J Head Trauma Rehabil",
    "topic": "epigenetic",
    "country": "Unspecified",
    "countryCode": "--",
    "affiliation": [
      "Author Affiliations: VISN 6 Mid-Atlantic Mental Illness, Research Education and Clinical Center (MIRECC), Durham, North Carolina (Dr Bourassa, Dr Martindale, MIRECC Workgroup, Dr Beckham, Dr Kimbrel, and Dr Rowland); Durham VA Health Care System, Durham, North Carolina (Dr Bourassa); Department of Psychology, Georgetown University, Washington, District of Columbia (Dr Bourassa); Salisbury VA Health Care System, Salisbury, North Carolina (Dr Martindale and Dr Rowland); Department of Translational Neuroscience, Wake Forest School of Medicine, Winston-Salem, North Carolina (Dr Martindale and Dr Rowland); Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, North Carolina (Ms Garrett and Dr Ashley-Koch); Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, North Carolina (Dr Beckham and Dr Kimbrel); and Health Services Research and Development ADAPT Center of Innovation, Durham, North Carolina (Dr Kimbrel)."
    ],
    "keywords": [
      "DNA methylation",
      "Humans",
      "Veterans",
      "Brain Injuries, Traumatic",
      "Female",
      "Male"
    ],
    "abstract": "PubMed record in The Journal of head trauma rehabilitation (2025). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "40816266",
    "doi": "10.1016/j.cell.2025.07.031",
    "year": 2025,
    "title": "Prevalent mesenchymal drift in aging and disease is reversed by partial reprogramming.",
    "authors": [
      "Lu JY",
      "Tu WB",
      "Li R",
      "Weng M",
      "Sanketi BD",
      "Yuan B",
      "Reddy P",
      "Rodriguez Esteban C",
      "Izpisua Belmonte JC"
    ],
    "journal": "Cell",
    "journalAbbr": "Cell",
    "topic": "mito",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "San Diego Institute of Science, Altos Labs, San Diego, CA, USA.",
      "San Diego Institute of Science, Altos Labs, San Diego, CA, USA; Salk Institute for Biological Studies, La Jolla, CA, USA."
    ],
    "keywords": [
      "reprogramming",
      "rejuvenation",
      "Humans",
      "Aging",
      "Cellular Reprogramming",
      "Animals"
    ],
    "abstract": "PubMed record in Cell (2025). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "40612666",
    "doi": "10.1016/j.gendis.2024.101490",
    "year": 2025,
    "title": "The role of the aging process and related factor EMP1 in promoting progression of resectable pancreatic cancer.",
    "authors": [
      "Zhang J",
      "Gu J",
      "Zhang T",
      "Xia R",
      "Li J",
      "Tan M",
      "Yang Y",
      "Xiang J",
      "Xie B",
      "Tang R",
      "Li W",
      "Wang X"
    ],
    "journal": "Genes & diseases",
    "journalAbbr": "Genes Dis",
    "topic": "agingdisease"
    , "organism": "Human and mouse models"
    , "modality": "Prognostic model; in vitro/in vivo experiments and tissue microarray"
    , "evidence_type": "Aging-related disease mechanism and prognostic study"
    , "longevity_relevance": "Indirect"
    , "scope_note": "Pancreatic-cancer aging study; not a general longevity cohort or single-cell atlas.",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "University of Chinese Academy of Sciences (UCAS) Chongqing School, Chongqing Medical University, Chongqing 401147, China.",
      "Institute of Hepatopancreatobiliary Surgery, Chongqing General Hospital, Chongqing University, Chongqing 401147, China."
    ],
    "keywords": [
      "aging",
      "longevity"
    ],
    "abstract": "PubMed record in Genes & diseases (2025). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "40122394",
    "doi": "10.1016/j.arr.2025.102737",
    "year": 2025,
    "title": "Conserved biological processes in partial cellular reprogramming: Relevance to aging and rejuvenation.",
    "authors": [
      "Avelar RA",
      "Palmer D",
      "Kulaga AY",
      "Fuellen G"
    ],
    "journal": "Ageing research reviews",
    "journalAbbr": "Ageing Res Rev",
    "topic": "senescence",
    "country": "Germany",
    "countryCode": "DE",
    "affiliation": [
      "Institute for Biostatistics and Informatics in Medicine and Ageing Research, Rostock University Medical Center, Germany. Electronic address: roberto.avelar@uni-rostock.de.",
      "Institute for Biostatistics and Informatics in Medicine and Ageing Research, Rostock University Medical Center, Germany. Electronic address: daniel.palmer@uni-rostock.de."
    ],
    "keywords": [
      "senescence",
      "autophagy",
      "mitochondria",
      "reprogramming",
      "rejuvenation",
      "biomarkers"
    ],
    "abstract": "PubMed record in Ageing research reviews (2025). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "39731913",
    "doi": "10.1016/j.devcel.2024.12.010",
    "year": 2025,
    "title": "Aging-induced changes in lymphatic muscle cell transcriptomes are associated with reduced pumping of peripheral collecting lymphatic vessels in mice.",
    "authors": [
      "Lei PJ",
      "Ruscic KJ",
      "Roh K",
      "Rajotte JJ",
      "O'Melia MJ",
      "Bouta EM",
      "Marquez M",
      "Pereira ER",
      "Kumar AS",
      "Razavi MS",
      "Zhou H",
      "Menzel L"
    ],
    "journal": "Developmental cell",
    "journalAbbr": "Dev Cell",
    "topic": "singlecell",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital Cancer Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.",
      "Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital Cancer Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA."
    ],
    "keywords": [
      "lifespan",
      "Animals",
      "Lymphatic Vessels",
      "Transcriptome",
      "Mice",
      "Aging"
    ],
    "abstract": "PubMed record in Developmental cell (2025). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "39731228",
    "doi": "10.1111/cpr.13797",
    "year": 2025,
    "title": "Single-Cell Transcriptomics Uncovers Core Signature for Regulating Mitochondrial Homeostasis During Testicular Ageing.",
    "authors": [
      "Xu W",
      "Huang Q",
      "Qi Y",
      "Hu Q",
      "Shen C",
      "Chen X",
      "Li J",
      "Xia Q",
      "Pan Z",
      "Zhang Y",
      "Han G",
      "Huang J"
    ],
    "journal": "Cell proliferation",
    "journalAbbr": "Cell Prolif",
    "topic": "singlecell",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Department of Geriatrics, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, China.",
      "Institute of Reproductive Medicine, Medical School of Nantong University, Nantong University, Nantong, China."
    ],
    "keywords": [
      "mitochondria",
      "Male",
      "Animals",
      "Testis",
      "Mitochondria",
      "Homeostasis"
    ],
    "abstract": "PubMed record in Cell proliferation (2025). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "39720856",
    "doi": "10.1111/acel.14446",
    "year": 2025,
    "title": "Nuclear respiratory factor-1 (NRF1) induction as a powerful strategy to deter mitochondrial dysfunction and senescence in mesenchymal stem cells.",
    "authors": [
      "Lee H",
      "Massaro M",
      "Abdelfattah N",
      "Baudo G",
      "Liu H",
      "Yun K",
      "Blanco E"
    ],
    "journal": "Aging cell",
    "journalAbbr": "Aging Cell",
    "topic": "singlecell",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Department of Nanomedicine, Houston Methodist Research Institute, Houston, Texas, USA.",
      "Department of Neurology, Houston Methodist Research Institute, Houston, Texas, USA."
    ],
    "keywords": [
      "senescence",
      "stem cell",
      "mitochondria",
      "Mesenchymal Stem Cells",
      "Cellular Senescence",
      "Nuclear Respiratory Factor 1"
    ],
    "abstract": "PubMed record in Aging cell (2025). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "39697114",
    "doi": "10.1080/15476286.2024.2440678",
    "year": 2025,
    "title": "The role and function of lncRNA in ageing-associated liver diseases.",
    "authors": [
      "Zarandi PK",
      "Ghiasi M",
      "Heiat M"
    ],
    "journal": "RNA biology",
    "journalAbbr": "RNA Biol",
    "topic": "senescence",
    "country": "Unspecified",
    "countryCode": "--",
    "affiliation": [
      "Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran.",
      "Cancer Biology Signaling Pathway Interest Group (CBSPIG), Universal Scientific Education and Research Network (USERN), Tehran, Iran."
    ],
    "keywords": [
      "senescence",
      "reprogramming",
      "RNA, Long Noncoding",
      "Humans",
      "Aging",
      "Liver Diseases"
    ],
    "abstract": "PubMed record in RNA biology (2025). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "39674503",
    "doi": "10.1016/j.jare.2024.12.018",
    "year": 2025,
    "title": "Insulin-like growth factor binding protein 7 identified in aged dental pulp by single-cell RNA sequencing.",
    "authors": [
      "Tong Z",
      "Wu J",
      "Gong Q",
      "Yuan Y",
      "Wang S",
      "Jiang W"
    ],
    "journal": "Journal of advanced research",
    "journalAbbr": "J Adv Res",
    "topic": "singlecell",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Hospital of Stomatology, Sun Yat-sen University, Guangzhou, Guangdong, China; Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-sen University, Guangzhou, Guangdong, China; Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, Guangdong, China.",
      "State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration & National Clinical Research Center for Oral Diseases & Shaanxi Key Laboratory of Stomatology, Department of Operative Dentistry & Endodontics, School of Stomatology, Fourth Military Medical University, No.145 Western Changle Road, Xi'an, Shaanxi 710032, China."
    ],
    "keywords": [
      "senescence",
      "stem cell",
      "Dental Pulp",
      "Humans",
      "Single-Cell Analysis",
      "Aging"
    ],
    "abstract": "PubMed record in Journal of advanced research (2025). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "39362333",
    "doi": "10.1016/j.jare.2024.09.026",
    "year": 2025,
    "title": "Unravelling the role of WRKY transcription factors in leaf senescence: Genetic and molecular insights.",
    "authors": [
      "Ahmad Z",
      "Ramakrishnan M",
      "Wang C",
      "Rehman S",
      "Shahzad A",
      "Wei Q"
    ],
    "journal": "Journal of advanced research",
    "journalAbbr": "J Adv Res",
    "topic": "senescence"
    , "organism": "Plant"
    , "modality": "Review"
    , "evidence_type": "Review"
    , "longevity_relevance": "Indirect"
    , "scope_note": "Plant leaf senescence review; not a mammalian longevity study.",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "State Key Laboratory of Tree Genetics and Breeding, Co-Innovation Centre for Sustainable Forestry in Southern China, Bamboo Research Institute, Key Laboratory of National Forestry and Grassland Administration on Subtropical Forest Biodiversity Conservation, School of Life Sciences, Nanjing Forestry University, Nanjing 210037, Jiangsu, China.",
      "National Key Laboratory of Wheat Improvement, Peking University Institute of Advanced Agricultural Sciences, Shandong Laboratory of Advanced Agriculture Sciences in Weifang, Weifang 261325, China."
    ],
    "keywords": [
      "senescence",
      "Transcription Factors",
      "Plant Leaves",
      "Gene Expression Regulation, Plant",
      "Plant Proteins",
      "Plant Senescence"
    ],
    "abstract": "PubMed record in Journal of advanced research (2025). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "39329281",
    "doi": "10.1097/CM9.0000000000003312",
    "year": 2025,
    "title": "Systemic comparison of molecular characteristics in different skin fibroblast senescent models.",
    "authors": [
      "Fang X",
      "Zhang S",
      "Wu M",
      "Luo Y",
      "Chen X",
      "Zhou Y",
      "Zhang Y",
      "Liu X",
      "Yao X"
    ],
    "journal": "Chinese medical journal",
    "journalAbbr": "Chin Med J (Engl)",
    "topic": "singlecell",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Department of Allergy and Rheumatology, Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs, Hospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, Jiangsu 210042, China."
    ],
    "keywords": [
      "senescence",
      "Humans",
      "Fibroblasts",
      "Cellular Senescence",
      "Skin",
      "Child"
    ],
    "abstract": "PubMed record in Chinese medical journal (2025). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "38940935",
    "doi": "10.1007/s10557-024-07590-0",
    "year": 2025,
    "title": "Heme Oxygenase-1, Cardiac Senescence, and Myocardial Infarction: A Critical Review of the Triptych.",
    "authors": [
      "Padda I",
      "Sethi Y",
      "Das M",
      "Fabian D",
      "Ralhan T",
      "Aziz D",
      "Sexton J",
      "Johal G"
    ],
    "journal": "Cardiovascular drugs and therapy",
    "journalAbbr": "Cardiovasc Drugs Ther",
    "topic": "senescence",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Richmond University Medical Center/Mount Sinai, Staten Island, NY, USA.",
      "PearResearch, Dehradun, India."
    ],
    "keywords": [
      "senescence",
      "Humans",
      "Heme Oxygenase-1",
      "Myocardial Infarction",
      "Cellular Senescence",
      "Animals"
    ],
    "abstract": "PubMed record in Cardiovascular drugs and therapy (2025). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "38887160",
    "doi": "10.1111/nmo.14848",
    "year": 2025,
    "title": "The human colon: Evidence for degenerative changes during aging and the physiological consequences.",
    "authors": [
      "Baidoo N",
      "Sanger GJ"
    ],
    "journal": "Neurogastroenterology and motility",
    "journalAbbr": "Neurogastroenterol Motil",
    "topic": "inflammaging",
    "country": "United Kingdom",
    "countryCode": "UK",
    "affiliation": [
      "School of Life Sciences, University of Westminster, London, UK.",
      "Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK."
    ],
    "keywords": [
      "inflammaging",
      "Humans",
      "Aging",
      "Colon",
      "Aged"
    ],
    "abstract": "PubMed record in Neurogastroenterology and motility (2025). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "38718895",
    "doi": "10.1016/j.jare.2024.05.006",
    "year": 2025,
    "title": "Crosstalk between endothelial cells and dermal papilla entails hair regeneration and angiogenesis during aging.",
    "authors": [
      "Zhou S",
      "Li Z",
      "Li X",
      "Ye Y",
      "Wang M",
      "Jiang J",
      "Tao L",
      "Wang Y",
      "Tung CT",
      "Chung Y",
      "Kim E",
      "Shen X"
    ],
    "journal": "Journal of advanced research",
    "journalAbbr": "J Adv Res",
    "topic": "singlecell",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Key Laboratory of Biorheological Science and Technology of Ministry of Education & 111 Project Laboratory of Biomechanics and Tissue Repair, College of Bioengineering, Chongqing University, Chongqing 400044, China. Electronic address: 202119021085@stu.cqu.edu.cn.",
      "Key Laboratory of Biorheological Science and Technology of Ministry of Education & 111 Project Laboratory of Biomechanics and Tissue Repair, College of Bioengineering, Chongqing University, Chongqing 400044, China. Electronic address: 202219021036@stu.cqu.edu.cn."
    ],
    "keywords": [
      "single-cell RNA-seq",
      "Animals",
      "Mice",
      "Endothelial Cells",
      "Regeneration",
      "Hair Follicle"
    ],
    "abstract": "PubMed record in Journal of advanced research (2025). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "39259812",
    "doi": "10.1126/scitranslmed.adg1777",
    "year": 2024,
    "title": "Targeted partial reprogramming of age-associated cell states improves markers of health in mouse models of aging.",
    "authors": [
      "Sahu SK",
      "Reddy P",
      "Lu J",
      "Shao Y",
      "Wang C",
      "Tsuji M",
      "Delicado EN",
      "Rodriguez Esteban C",
      "Belmonte JCI"
    ],
    "journal": "Science translational medicine",
    "journalAbbr": "Sci Transl Med",
    "topic": "senescence",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Altos Labs, San Diego, CA 92122, USA.",
      "Universidad Católica San Antonio de Murcia, Guadalupe 30107, Spain."
    ],
    "keywords": [
      "senescence",
      "stem cell",
      "reprogramming",
      "rejuvenation",
      "Animals",
      "Kruppel-Like Factor 4"
    ],
    "abstract": "PubMed record in Science translational medicine (2024). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "39169434",
    "doi": "10.1111/acel.14308",
    "year": 2024,
    "title": "Single-cell transcriptomic atlas of taste papilla aging.",
    "authors": [
      "Ren W",
      "Li W",
      "Cha X",
      "Wang S",
      "Cai B",
      "Wang T",
      "Li F",
      "Li T",
      "Xie Y",
      "Xu Z",
      "Wang Z",
      "Liu H"
    ],
    "journal": "Aging cell",
    "journalAbbr": "Aging Cell",
    "topic": "singlecell",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Department of Otolaryngology, The Second Affiliated Hospital of the Naval Medical University (Shanghai Changzheng Hospital), Shanghai, China.",
      "ENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, China."
    ],
    "keywords": [
      "Animals",
      "Mice",
      "Aging",
      "Transcriptome",
      "Taste Buds",
      "Single-Cell Analysis"
    ],
    "abstract": "PubMed record in Aging cell (2024). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "38381405",
    "doi": "10.1089/cell.2023.0072",
    "year": 2024,
    "title": "Gene Therapy-Mediated Partial Reprogramming Extends Lifespan and Reverses Age-Related Changes in Aged Mice.",
    "authors": [
      "Macip CC",
      "Hasan R",
      "Hoznek V",
      "Kim J",
      "Lu YR",
      "Metzger LE",
      "Sethna S",
      "Davidsohn N"
    ],
    "journal": "Cellular reprogramming",
    "journalAbbr": "Cell Reprogram",
    "topic": "genetherapy",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Rejuvenate Bio, San Diego, California, USA.",
      "Department of Biology, Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, USA."
    ],
    "keywords": [
      "lifespan",
      "healthspan",
      "reprogramming",
      "Aged",
      "Male",
      "Humans"
    ],
    "abstract": "PubMed record in Cellular reprogramming (2024). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "38366188",
    "doi": "10.1093/procel/pwad067",
    "year": 2024,
    "title": "Single-cell transcriptomic Atlas of aging macaque ocular outflow tissues.",
    "authors": [
      "Wu J",
      "Wang C",
      "Sun S",
      "Ren T",
      "Pan L",
      "Liu H",
      "Hou S",
      "Wu S",
      "Yan X",
      "Zhang J",
      "Zhao X",
      "Liu W"
    ],
    "journal": "Protein & cell",
    "journalAbbr": "Protein Cell",
    "topic": "singlecell",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing 100730, China.",
      "State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China."
    ],
    "keywords": [
      "mitochondria",
      "Animals",
      "Aging",
      "Trabecular Meshwork",
      "Transcriptome",
      "Single-Cell Analysis"
    ],
    "abstract": "PubMed record in Protein & cell (2024). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "38102454",
    "doi": "10.1038/s43587-023-00539-2",
    "year": 2024,
    "title": "Mechanisms, pathways and strategies for rejuvenation through epigenetic reprogramming.",
    "authors": [
      "Cipriano A",
      "Moqri M",
      "Maybury-Lewis SY",
      "Rogers-Hammond R",
      "de Jong TA",
      "Parker A",
      "Rasouli S",
      "Schöler HR",
      "Sinclair DA",
      "Sebastiano V"
    ],
    "journal": "Nature aging",
    "journalAbbr": "Nat Aging",
    "topic": "genetherapy",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Department of Obstetrics & Gynecology, Stanford School of Medicine, Stanford University, Stanford, CA, USA.",
      "Institute for Stem Cell Biology and Regenerative Medicine, Stanford School of Medicine, Stanford, CA, USA."
    ],
    "keywords": [
      "reprogramming",
      "rejuvenation",
      "Humans",
      "Animals",
      "Mice",
      "Rejuvenation"
    ],
    "abstract": "PubMed record in Nature aging (2024). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "37993056",
    "doi": "10.1016/j.mad.2023.111887",
    "year": 2023,
    "title": "The skin of the naked mole-rat and its resilience against aging and cancer.",
    "authors": [
      "Wlaschek M",
      "Singh K",
      "Maity P",
      "Scharffetter-Kochanek K"
    ],
    "journal": "Mechanisms of ageing and development",
    "journalAbbr": "Mech Ageing Dev",
    "topic": "singlecell",
    "country": "Germany",
    "countryCode": "DE",
    "affiliation": [
      "Department of Dermatology and Allergic Diseases, Ulm University, Ulm, Germany. Electronic address: meinhard.wlaschek@uni-ulm.de.",
      "Department of Dermatology and Allergic Diseases, Ulm University, Ulm, Germany. Electronic address: Karmveer.singh@uni-ulm.de."
    ],
    "keywords": [
      "naked mole-rat",
      "longevity",
      "Animals",
      "Resilience, Psychological",
      "Aging",
      "Longevity"
    ],
    "abstract": "PubMed record in Mechanisms of ageing and development (2023). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "37612507",
    "doi": "10.1038/s41586-023-06463-0",
    "year": 2023,
    "title": "Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice.",
    "authors": [
      "Zhang Z",
      "Tian X",
      "Lu JY",
      "Boit K",
      "Ablaeva J",
      "Zakusilo FT",
      "Emmrich S",
      "Firsanov D",
      "Rydkina E",
      "Biashad SA",
      "Lu Q",
      "Tyshkovskiy A"
    ],
    "journal": "Nature",
    "journalAbbr": "Nature",
    "topic": "singlecell",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Department of Biology, University of Rochester, Rochester, NY, USA.",
      "Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA."
    ],
    "keywords": [
      "naked mole-rat",
      "longevity",
      "lifespan",
      "healthspan",
      "Animals",
      "Mice"
    ],
    "abstract": "PubMed record in Nature (2023). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "37329949",
    "doi": "10.1016/j.molmet.2023.101755",
    "year": 2023,
    "title": "Chronic inflammation and the hallmarks of aging.",
    "authors": [
      "Baechle JJ",
      "Chen N",
      "Makhijani P",
      "Winer S",
      "Furman D",
      "Winer DA"
    ],
    "journal": "Molecular metabolism",
    "journalAbbr": "Mol Metab",
    "topic": "inflammaging",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Buck Artificial Intelligence Platform, the Buck Institute for Research on Aging, Novato, CA, USA.",
      "Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada; Division of Cellular & Molecular Biology, Diabetes Research Group, Toronto General Hospital Research Institute (TGHRI), University Health Network, Toronto, ON, Canada."
    ],
    "keywords": [
      "inflammaging",
      "autophagy",
      "Humans",
      "Aged",
      "Inflammation",
      "Anti-Inflammatory Agents"
    ],
    "abstract": "PubMed record in Molecular metabolism (2023). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "37269831",
    "doi": "10.1016/j.cell.2023.05.002",
    "year": 2023,
    "title": "Distinct longevity mechanisms across and within species and their association with aging.",
    "authors": [
      "Tyshkovskiy A",
      "Ma S",
      "Shindyapina AV",
      "Tikhonov S",
      "Lee SG",
      "Bozaykut P",
      "Castro JP",
      "Seluanov A",
      "Schork NJ",
      "Gorbunova V",
      "Dmitriev SE",
      "Miller RA"
    ],
    "journal": "Cell",
    "journalAbbr": "Cell",
    "topic": "mito",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Belozersky Institute of Physico-Chemical Biology, Moscow State University, Moscow 119234, Russia.",
      "Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA."
    ],
    "keywords": [
      "mitochondria",
      "longevity",
      "lifespan",
      "healthspan",
      "biomarkers",
      "Animals"
    ],
    "abstract": "PubMed record in Cell (2023). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "36933008",
    "doi": "10.1093/procel/pwac058",
    "year": 2023,
    "title": "Single-cell transcriptomic atlas of mouse cochlear aging.",
    "authors": [
      "Sun G",
      "Zheng Y",
      "Fu X",
      "Zhang W",
      "Ren J",
      "Ma S",
      "Sun S",
      "He X",
      "Wang Q",
      "Ji Z",
      "Cheng F",
      "Yan K"
    ],
    "journal": "Protein & cell",
    "journalAbbr": "Protein Cell",
    "topic": "singlecell",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.",
      "University of Chinese Academy of Sciences, Beijing 100049, China."
    ],
    "keywords": [
      "proteostasis",
      "Mice",
      "Animals",
      "Transcriptome",
      "Aging",
      "Cochlea"
    ],
    "abstract": "PubMed record in Protein & cell (2023). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "36871150",
    "doi": "10.1002/bies.202200208",
    "year": 2023,
    "title": "Epigenetic rejuvenation by partial reprogramming.",
    "authors": [
      "Puri D",
      "Wagner W"
    ],
    "journal": "BioEssays : news and reviews in molecular, cellular and developmental biology",
    "journalAbbr": "Bioessays",
    "topic": "senescence",
    "country": "Germany",
    "countryCode": "DE",
    "affiliation": [
      "Helmholtz-Institute for Biomedical Engineering, RWTH Aachen University, Medical Faculty, Aachen, Germany.",
      "Institute for Stem Cell Biology, RWTH Aachen University Medical School, Aachen, Germany."
    ],
    "keywords": [
      "senescence",
      "telomere",
      "epigenetic clock",
      "stem cell",
      "reprogramming",
      "rejuvenation"
    ],
    "abstract": "PubMed record in BioEssays : news and reviews in molecular, cellular and developmental biology (2023). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "36599349",
    "doi": "10.1016/j.cell.2022.11.001",
    "year": 2023,
    "title": "Hallmarks of aging: An expanding universe.",
    "authors": [
      "López-Otín C",
      "Blasco MA",
      "Partridge L",
      "Serrano M",
      "Kroemer G"
    ],
    "journal": "Cell",
    "journalAbbr": "Cell",
    "topic": "senescence",
    "country": "United Kingdom",
    "countryCode": "UK",
    "affiliation": [
      "Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo, Oviedo, Spain; Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain. Electronic address: clo@uniovi.es.",
      "Telomeres and Telomerase Group, Molecular Oncology Program, Spanish National Cancer Centre (CNIO), Madrid, Spain."
    ],
    "keywords": [
      "senescence",
      "telomere",
      "stem cell",
      "autophagy",
      "proteostasis",
      "mitochondria"
    ],
    "abstract": "PubMed record in Cell (2023). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "36599298",
    "doi": "10.1016/j.cmet.2022.11.001",
    "year": 2023,
    "title": "Meta-hallmarks of aging and cancer.",
    "authors": [
      "López-Otín C",
      "Pietrocola F",
      "Roiz-Valle D",
      "Galluzzi L",
      "Kroemer G"
    ],
    "journal": "Cell metabolism",
    "journalAbbr": "Cell Metab",
    "topic": "senescence",
    "country": "Spain",
    "countryCode": "ES",
    "affiliation": [
      "Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo, Oviedo, Spain; Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain. Electronic address: clo@uniovi.es.",
      "Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden."
    ],
    "keywords": [
      "senescence",
      "telomere",
      "stem cell",
      "autophagy",
      "Humans",
      "Aged"
    ],
    "abstract": "PubMed record in Cell metabolism (2023). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "36318672",
    "doi": "10.1146/annurev-animal-050322-074744",
    "year": 2023,
    "title": "The Naked Mole-Rat as a Model for Healthy Aging.",
    "authors": [
      "Oka K",
      "Yamakawa M",
      "Kawamura Y",
      "Kutsukake N",
      "Miura K"
    ],
    "journal": "Annual review of animal biosciences",
    "journalAbbr": "Annu Rev Anim Biosci",
    "topic": "singlecell",
    "country": "Japan",
    "countryCode": "JP",
    "affiliation": [
      "Department of Aging and Longevity Research, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan; email: okaori@kumamoto-u.ac.jp, kawamuray@kumamoto-u.ac.jp, miurak@kumamoto-u.ac.jp.",
      "Department of Evolutionary Studies of Biosystems, Sokendai (The Graduate University for Advanced Studies), Kanagawa, Japan; email: yamakawa_masanori@soken.ac.jp, kutsu@soken.ac.jp."
    ],
    "keywords": [
      "naked mole-rat",
      "longevity",
      "Animals",
      "Healthy Aging",
      "Aging",
      "Longevity"
    ],
    "abstract": "PubMed record in Annual review of animal biosciences (2023). Open the PMID link for the publisher abstract and full bibliographic metadata.",
    "citations": 0,
    "ifactor": 1,
    "source": "PubMed"
  },
  {
    "pmid": "37118377",
    "doi": "10.1038/s43587-022-00183-2",
    "year": 2022,
    "title": "In vivo partial reprogramming alters age-associated molecular changes during physiological aging in mice.",
    "authors": [
      "Browder KC",
      "Reddy P",
      "Yamamoto M",
      "Haghani A",
      "Guillen IG",
      "Sahu S",
      "Wang C",
      "Luque Y",
      "Prieto J",
      "Shi L",
      "Shojima K",
      "Hishida T"
    ],
    "journal": "Nature aging",
    "journalAbbr": "Nat Aging",
    "topic": "senescence",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Immunology Discovery, Genentech, Inc., South San Francisco, CA, USA.",
      "Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA."
    ],
    "keywords": [
      "senescence",
      "epigenetic clock",
      "reprogramming",
      "Animals",
      "Mice",
      "Cellular Reprogramming"
    ],
    "abstract": "PubMed record in Nature aging (2022). Open the PMID link for the publisher abstract and full bibliographic metadata.",
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    "year": 2021,
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      "Cuervo AM"
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    "topic": "proteostasis",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, NY, USA; Institute for Aging Studies, Albert Einstein College of Medicine, NY, USA.",
      "Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, NY, USA; Institute for Aging Studies, Albert Einstein College of Medicine, NY, USA; Departmento de Bioquimica y Biologia Molecular, Universidad de Cordoba, Cordoba, Spain."
    ],
    "keywords": [
      "autophagy",
      "proteostasis",
      "lifespan",
      "healthspan",
      "Aging",
      "Autophagy"
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    "abstract": "PubMed record in Ageing research reviews (2021). Open the PMID link for the publisher abstract and full bibliographic metadata.",
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    "doi": "10.1007/978-3-030-65943-1_8",
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    "authors": [
      "Buffenstein R",
      "Craft W"
    ],
    "journal": "Advances in experimental medicine and biology",
    "journalAbbr": "Adv Exp Med Biol",
    "topic": "singlecell",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Calico Life Sciences LLC, South San Francisco, CA, USA. rbuffen@calicolabs.com.",
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      "longevity",
      "lifespan",
      "healthspan",
      "Aging",
      "Animals"
    ],
    "abstract": "PubMed record in Advances in experimental medicine and biology (2021). Open the PMID link for the publisher abstract and full bibliographic metadata.",
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    "pmid": "33450206",
    "doi": "10.1016/j.cell.2020.12.028",
    "year": 2021,
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    "authors": [
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    "journal": "Cell",
    "journalAbbr": "Cell",
    "topic": "telomere",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.",
      "Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address: rdepinho@mdanderson.org."
    ],
    "keywords": [
      "telomere",
      "Aging",
      "Animals",
      "Cellular Senescence",
      "Genomic Instability",
      "Health"
    ],
    "abstract": "PubMed record in Cell (2021). Open the PMID link for the publisher abstract and full bibliographic metadata.",
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    "pmid": "33238152",
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    "year": 2021,
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      "He Y",
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      "Yu N",
      "Huang J"
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    "journal": "Developmental cell",
    "journalAbbr": "Dev Cell",
    "topic": "singlecell",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China.",
      "Division of Plastic Surgery, Peking Union Medical College Hospital, Beijing 100032, China."
    ],
    "keywords": [
      "senescence",
      "Adolescent",
      "Adult",
      "Aged",
      "Dermis",
      "Epidermis"
    ],
    "abstract": "PubMed record in Developmental cell (2021). Open the PMID link for the publisher abstract and full bibliographic metadata.",
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    "pmid": "32913304",
    "doi": "10.1038/s41422-020-00412-6",
    "year": 2021,
    "title": "Single-cell transcriptomic atlas of primate cardiopulmonary aging.",
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      "Zhang S"
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    "journal": "Cell research",
    "journalAbbr": "Cell Res",
    "topic": "singlecell",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.",
      "State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China."
    ],
    "keywords": [
      "Aging",
      "Alveolar Epithelial Cells",
      "Angiotensin-Converting Enzyme 2",
      "Animals",
      "Ascorbic Acid",
      "COVID-19"
    ],
    "abstract": "PubMed record in Cell research (2021). Open the PMID link for the publisher abstract and full bibliographic metadata.",
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    "pmid": "32669714",
    "doi": "10.1038/s41586-020-2496-1",
    "year": 2020,
    "title": "A single-cell transcriptomic atlas characterizes ageing tissues in the mouse.",
    "authors": [
      "Tabula Muris Consortium"
    ],
    "journal": "Nature",
    "journalAbbr": "Nature",
    "topic": "singlecell",
    "country": "Unspecified",
    "countryCode": "--",
    "affiliation": [
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    ],
    "keywords": [
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      "lifespan",
      "Aging",
      "Animals",
      "Cellular Senescence",
      "DNA Mutational Analysis"
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    "abstract": "PubMed record in Nature (2020). Open the PMID link for the publisher abstract and full bibliographic metadata.",
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    "doi": "10.1016/j.cell.2020.01.009",
    "year": 2020,
    "title": "Single-Cell Transcriptomic Atlas of Primate Ovarian Aging.",
    "authors": [
      "Wang S",
      "Zheng Y",
      "Li J",
      "Yu Y",
      "Zhang W",
      "Song M",
      "Liu Z",
      "Min Z",
      "Hu H",
      "Jing Y",
      "He X",
      "Sun L"
    ],
    "journal": "Cell",
    "journalAbbr": "Cell",
    "topic": "singlecell",
    "country": "China",
    "countryCode": "CN",
    "affiliation": [
      "State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; Beijing Institute for Brain Disorders, Advanced Innovation Center for Human Brain Protection, National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital Capital Medical University, Beijing 100053, China; University of Chinese Academy of Sciences, Beijing 100049, China.",
      "Beijing Advanced Innovation Center for Genomics, College of Life Sciences, Peking University, Beijing 100871, China; Biomedical Institute for Pioneering Investigation via Convergence, Ministry of Education Key Laboratory of Cell Proliferation and Differentiation, Beijing 100871, China; Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China."
    ],
    "keywords": [
      "biomarkers",
      "Aged",
      "Aging",
      "Animals",
      "Antioxidants",
      "Apoptosis"
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    "abstract": "PubMed record in Cell (2020). Open the PMID link for the publisher abstract and full bibliographic metadata.",
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    "pmid": "30478397",
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    "year": 2019,
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    "journal": "Nature immunology",
    "journalAbbr": "Nat Immunol",
    "topic": "nad",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Department of Neurology & Neurological Sciences, Stanford School of Medicine, Stanford, CA, USA.",
      "Neurosciences Graduate Program, Stanford University, Stanford, CA, USA."
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    "keywords": [
      "NAD",
      "mitochondria",
      "Aging",
      "Animals",
      "Cells, Cultured",
      "Homeostasis"
    ],
    "abstract": "PubMed record in Nature immunology (2019). Open the PMID link for the publisher abstract and full bibliographic metadata.",
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    "topic": "nad",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Georgia Regents University, Augusta, GA 30912, United States.",
      "Georgia Regents University, Augusta, GA 30912, United States. Electronic address: RRaju@gru.edu."
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    "keywords": [
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      "sirtuins",
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      "longevity"
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    "abstract": "PubMed record in Biochimica et biophysica acta (2015). Open the PMID link for the publisher abstract and full bibliographic metadata.",
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      "Mercken EM",
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    "journal": "Cell",
    "journalAbbr": "Cell",
    "topic": "nad",
    "country": "United States",
    "countryCode": "US",
    "affiliation": [
      "Glenn Labs for the Biological Mechanisms of Aging, Department of Genetics, Harvard Medical School, Boston, MA 02115, USA; Center for Neurosciences and Cell Biology, 3004-517 Coimbra, Portugal; Department of Life Sciences, Faculty of Science and Technology, University of Coimbra, 3004-517 Coimbra, Portugal.",
      "Glenn Labs for the Biological Mechanisms of Aging, Department of Genetics, Harvard Medical School, Boston, MA 02115, USA."
    ],
    "keywords": [
      "NAD",
      "mitochondria",
      "reprogramming",
      "AMP-Activated Protein Kinases",
      "Aging",
      "Animals"
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    "abstract": "PubMed record in Cell (2013). Open the PMID link for the publisher abstract and full bibliographic metadata.",
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    "year": 2013,
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      "Blasco MA",
      "Partridge L",
      "Serrano M",
      "Kroemer G"
    ],
    "journal": "Cell",
    "journalAbbr": "Cell",
    "topic": "senescence",
    "country": "Spain",
    "countryCode": "ES",
    "affiliation": [
      "Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo, Oviedo, Spain."
    ],
    "keywords": [
      "senescence",
      "telomere",
      "stem cell",
      "proteostasis",
      "mitochondria",
      "Aging"
    ],
    "abstract": "PubMed record in Cell (2013). Open the PMID link for the publisher abstract and full bibliographic metadata.",
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    "source": "PubMed"
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