Goblet cells

Goblet cells are specialized unicellular mucus-secreting glands found within simple columnar epithelia of the respiratory and intestinal tracts. They have a characteristic goblet shape, with a basal nucleus and an apical region packed with mucin granules. They secrete mucins, which hydrate and form the protective mucus layer that traps particles, lubricates surfaces, and protects the epithelium from pathogens and damage.