⚙ How is this computed? Methods: Correlation Analysis
SP121 · 15- and 12-gene sets

Longevity vs aging scores

Spearman ρ between a 15-gene longevity score and a 12-gene aging score in the SP121 human atlas, reported at system, tissue, and cell-type level. Cell-level association only.

Human · SP121Spearman ρ1,246,365 cells
Open human atlas → Gene-set definitions →
SP121 Human cell atlas input
3 levels System · tissue · cell type
Full atlas 1,246,365-cell versioned analysis
Analysis context Human · SP121 Loading versioned analysis manifest…
Run — Open atlas
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Input, score and quality controls

Longevity gene set
Aging gene set
Evidence snapshot

Analysis summary

Waiting for manifest
Overall status Loading… Versioned artifact status
Source cells — Human SP121 input
Mapped genes — Longevity / aging sets
Independent support — Donors / samples
Association catalogue

Correlation result table

Analysis in progress

Correlation results are being computed

The page will load the versioned summary when the run reaches ready. No placeholder coefficients are shown.

Waiting for the analysis artifact…

Coefficient display only: this versioned run does not report p or q values because donor/sample-level independent replicates are unavailable. n is the number of cells.

Method

What ρ is

Cell-level Spearman correlation of the two gene-set scores in SP121. Not a causal or ligand–receptor result.

  • Independent support: donor/sample aggregation is preferred over treating cells from one donor as independent.
  • Multiplicity: group-level tests must report BH-FDR alongside effect size.
  • Insufficient support: groups below the minimum observation threshold remain not estimable.