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Cell Type
Cell Type Overview
Osteoblasts are bone-forming cells of mesenchymal origin that synthesize and mineralize bone matrix by secreting type I collagen and regulators of hydroxyapatite deposition. They mature into osteocytes embedded within bone or into bone-lining cells, and they control osteoclast formation through RANKL and OPG signaling. Their declining activity with age contributes to skeletal fragility.
Cell Type UMAP Atlas & Gene Explorer
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