๐งฌ
Cell Type
Effector chondrocytes
EC
Stromal cells
Cell Type Overview
This likely refers to chondrocytes in a state of active matrix degradation or inflammation, analogous to "effector" immune cells. In osteoarthritis or rheumatoid arthritis, some chondrocytes adopt a catabolic phenotype, expressing enzymes like matrix metalloproteinases (MMPs) and aggrecanases (ADAMTS) that break down the cartilage extracellular matrix, contributing to joint destruction.
Cell Type UMAP Atlas & Gene Explorer
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Cell Distribution โ WebGL
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Expression
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