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Cell Type
Pre-hypertrophic chondrocytes
preHTC
Stromal cells
Cell Type Overview
A transitional state in the growth plate between proliferating and hypertrophic chondrocytes. They have stopped dividing and begin to express early markers of hypertrophy, such as Indian hedgehog (Ihh), which is a key signaling molecule that regulates the pace of endochondral ossification and coordinates chondrocyte differentiation with osteoblast recruitment.
Cell Type UMAP Atlas & Gene Explorer
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Expression
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