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Cell Type
Species / House mouse / Distal convoluted tubule cells
Distal convoluted tubule cells
Major003CT026Z
Epithelial cells
Cell Type Overview
Cells of the distal convoluted tubule (DCT) in the nephron. They are responsible for fine-tuning electrolyte balance. They actively reabsorb sodium and chloride (via the Na-Cl cotransporter, NCC) and are a major site for parathyroid hormone (PTH)-regulated calcium reabsorption. Their activity is crucial for maintaining blood pressure, potassium, calcium, and magnesium homeostasis.
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