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Cell Type
Species / House mouse / Pancreas ductal cells
Pancreas ductal cells
Major003CT054AA
Epithelial cells
Cell Type Overview
Pancreatic ductal cells form the lining of the ductal network that transports digestive enzymes from the acini and bicarbonate-rich fluid from the centroacinar cells to the duodenum. They modify the pancreatic juice by secreting bicarbonate ions (HCO3-) to neutralize gastric acid. They express CFTR, and mutations here cause cystic fibrosis-related pancreatic disease. They can also act as progenitor cells in certain contexts.
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Cell Type
Expression
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