Tabula Muris Senis DS Dataset
Aging Atlas / House mouse / Tabula Muris Senis

Tabula Muris Senis

A single-cell transcriptomic atlas of ageing mouse tissues
Aging dataset
356,213
Released cells
155
Cell types
23
Source records
32669714
PMID
Liver
Requested tissue
Statistics Analysis

Dataset overview

This page is scoped to the official full Tabula Muris Senis release (PMID 32669714), not the full SP124 mouse integration. It integrates droplet and FACS profiles spanning 1, 3, 18, 21, 24, and 30 months of age across the study tissues. The requested alias Data0451 identifies the Liver source record; it does not filter the integrated UMAP to that tissue. The validated release contains 356,213 cells and 20,116 genes.

Tabula Muris Senis single-cell atlas & gene explorer

Data processing BioID-standardised Input: Processed matrix Methods Per-dataset records
Scientific scope guardrail This release contains only Tabula Muris Senis cells (PMID 32669714). The stable dataset URL is content.php?SP_ID=SP124&dataset=tabula-muris-senis. Requested alias Data0451 records Liver metadata; the UMAP below remains the integrated TMS dataset and is not presented as a tissue-specific subset. Age-group composition is shown only when validated author metadata are available; it is descriptive and not a differential-expression result.
23 LACA registered source records

Age group composition

1m: 25,9803m: 90,12018m: 78,67221m: 36,55624m: 69,21130m: 55,674

Sex composition

male: 235,645female: 120,568

Protocol composition

droplet: 245,389facs: 110,824

Tissue composition

Marrow: 54,737Spleen: 39,552Limb Muscle: 32,722Lung: 29,758Tongue: 24,415Kidney: 23,480Mammary Gland: 15,577Brain Myeloid: 13,417Thymus: 13,322Bladder: 11,377Trachea: 11,136Large Intestine: 10,198Liver: 10,153Heart: 9,669Pancreas: 9,585Skin: 9,314Heart and Aorta: 8,613Brain Non-Myeloid: 7,249Fat: 6,777SCAT: 3,755GAT: 3,406MAT: 3,014BAT: 2,223Diaphragm: 1,858Aorta: 906
Age, sex, protocol, and tissue counts are descriptive compositions from author metadata. The gene-expression explorer is dataset-wide; age-stratified expression and differential-expression analyses have not been performed. A future age-DEG analysis must use audited mouse-level biological replicates and control for tissue, protocol, and sex.
Nature DOI PubMed 32669714 GEO GSE149590
๐Ÿงฌ
Size
Opacity
Loading UMAP for Tabula Muris Senisโ€ฆ
Cell Distribution โ€” WebGL
Cells: 0Types: 0Zoom: 1.0x
โ†’ UMAP_1
โ†‘ UMAP_2
0
Max
Loading...

Cell Types

Loading cell types...
โ€”
Tissues
โ€”
Systems
โ€”
Samples
0
Total Cells
0
Cell Types

Dataset source records

Whitelisted Tabula Muris Senis tissue records
23Datasets
DataID โ†• Latin Name โ†• Folder ID โ†• Tissue โ†• Title โ†• Detail QC Analysis
Data0411 Mus musculus Mus_musculus_32669714_2020_Rank001 Aorta A single-cell transcriptomic atlas characterizes ageing tissues in the mouse. Atlas Analysis
Data0418 Mus musculus Mus_musculus_32669714_2020_Rank002 Brown adipose tissue A single-cell transcriptomic atlas characterizes ageing tissues in the mouse. Atlas Analysis
Data0415 Mus musculus Mus_musculus_32669714_2020_Rank003 Bladder A single-cell transcriptomic atlas characterizes ageing tissues in the mouse. Atlas Analysis
Data0417 Mus musculus Mus_musculus_32669714_2020_Rank004 Brain A single-cell transcriptomic atlas characterizes ageing tissues in the mouse. Atlas Analysis
Data0423 Mus musculus Mus_musculus_32669714_2020_Rank005 Diaphragm A single-cell transcriptomic atlas characterizes ageing tissues in the mouse. Atlas Analysis
Data0428 Mus musculus Mus_musculus_32669714_2020_Rank006 Gonadal adipose tissue A single-cell transcriptomic atlas characterizes ageing tissues in the mouse. Atlas Analysis
Data0431 Mus musculus Mus_musculus_32669714_2020_Rank007 Heart A single-cell transcriptomic atlas characterizes ageing tissues in the mouse. Atlas Analysis
Data0447 Mus musculus Mus_musculus_32669714_2020_Rank008 Kidney A single-cell transcriptomic atlas characterizes ageing tissues in the mouse. Atlas Analysis
Data0448 Mus musculus Mus_musculus_32669714_2020_Rank009 Large intestine A single-cell transcriptomic atlas characterizes ageing tissues in the mouse. Atlas Analysis
Data0449 Mus musculus Mus_musculus_32669714_2020_Rank010 Limb muscle A single-cell transcriptomic atlas characterizes ageing tissues in the mouse. Atlas Analysis
Data0451 Mus musculus Mus_musculus_32669714_2020_Rank011 Liver A single-cell transcriptomic atlas characterizes ageing tissues in the mouse. Atlas Analysis
Data0453 Mus musculus Mus_musculus_32669714_2020_Rank012 Lung A single-cell transcriptomic atlas characterizes ageing tissues in the mouse. Atlas Analysis
Data0456 Mus musculus Mus_musculus_32669714_2020_Rank013 Mammary A single-cell transcriptomic atlas characterizes ageing tissues in the mouse. Atlas Analysis
Data0458 Mus musculus Mus_musculus_32669714_2020_Rank014 Marrow A single-cell transcriptomic atlas characterizes ageing tissues in the mouse. Atlas Analysis
Data0471 Mus musculus Mus_musculus_32669714_2020_Rank015 Mesenteric adipose tissue A single-cell transcriptomic atlas characterizes ageing tissues in the mouse. Atlas Analysis
Data0494 Mus musculus Mus_musculus_32669714_2020_Rank016 Pancreas A single-cell transcriptomic atlas characterizes ageing tissues in the mouse. Atlas Analysis
Data0521 Mus musculus Mus_musculus_32669714_2020_Rank017 Subcutaneous adipose tissue A single-cell transcriptomic atlas characterizes ageing tissues in the mouse. Atlas Analysis
Data0508 Mus musculus Mus_musculus_32669714_2020_Rank018 Skin A single-cell transcriptomic atlas characterizes ageing tissues in the mouse. Atlas Analysis
Data0511 Mus musculus Mus_musculus_32669714_2020_Rank019 Spleen A single-cell transcriptomic atlas characterizes ageing tissues in the mouse. Atlas Analysis
Data0540 Mus musculus Mus_musculus_32669714_2020_Rank020 Thymus A single-cell transcriptomic atlas characterizes ageing tissues in the mouse. Atlas Analysis
Data0542 Mus musculus Mus_musculus_32669714_2020_Rank021 Tongue A single-cell transcriptomic atlas characterizes ageing tissues in the mouse. Atlas Analysis
Data0543 Mus musculus Mus_musculus_32669714_2020_Rank022 Trachea A single-cell transcriptomic atlas characterizes ageing tissues in the mouse. Atlas Analysis
Data1453 Mus musculus Tabula_Muris_Senis 23 tissues A single-cell transcriptomic atlas characterizes ageing tissues in the mouse. Atlas Analysis

๐Ÿ“„ Overview

โ† Back to Aging Atlas
Cell Type
Expression
Coords