Osteoclasts ๐Ÿงฌ Cell Type
Species / Hamadryas baboon / Osteoclasts

Osteoclasts

Ocl
Stromal cells
Major004CT029AA
Cell Type ID
Ocl
Abbreviation
1
Tissues
SP2213
Species
Statistics Analysis

Cell Type Overview

Osteoclasts are large multinucleated cells of the monocyte/macrophage lineage that resorb bone by secreting protons and lysosomal enzymes such as cathepsin K onto the bone surface. Together with bone-forming osteoblasts, they maintain skeletal homeostasis through continuous remodeling. Excessive osteoclast activity drives bone loss in osteoporosis and inflammatory bone disease.

Cell Type UMAP Atlas & Gene Explorer

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