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Cell Type
Cell Type Overview
Corticotropes are endocrine cells in the anterior pituitary gland (adenohypophysis) that produce and secrete adrenocorticotropic hormone (ACTH). ACTH is derived from the precursor pro-opiomelanocortin (POMC). In response to corticotropin-releasing hormone (CRH) from the hypothalamus, corticotropes release ACTH into the bloodstream, which then stimulates the adrenal cortex to produce glucocorticoids (like cortisol), key stress hormones.
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