Principal cells ๐Ÿงฌ Cell Type
Species / Gray mouse lemur / Principal cells

Principal cells

Major003CT061AA
Epithelial cells
Major003CT061AA
Cell Type ID
SP301
Species
Statistics Analysis

Cell Type Overview

In the kidney's collecting duct, principal cells are the most abundant cell type. They are responsible for the final regulation of water, sodium, and potassium balance. They express aquaporin-2 channels on their apical membrane (inserted in response to vasopressin/ADH) for water reabsorption. They also reabsorb sodium via ENaC channels and secrete potassium, processes regulated by aldosterone.

Cell Type UMAP Atlas & Gene Explorer

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