GSM5528500

Dataset: gse182409 • Sample: T004 • Status: Pregnancy-stage cohort
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Quality Control Metrics

89,833,785 Total counts Group median: 70,855,220 • 90.1%ile (↑ High)
29,338 Detected genes Group median: 31,576 • 29.8%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 1.0%ile (↓ Low)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

60.0Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.23
bar=donor   line=cohort median 		9.31 45.9%
CETP Lipid Metabolism 1.98
bar=donor   line=cohort median 		1.18 89.3%
SIRT6 Sirtuin Family 2.38
bar=donor   line=cohort median 		2.22 72.8%
SIRT1 Sirtuin Family 5.88
bar=donor   line=cohort median 		5.50 96.9%
SIRT3 Sirtuin Family 2.51
bar=donor   line=cohort median 		2.33 76.2%
IGF1R Insulin/IGF-1 Signaling 7.26
bar=donor   line=cohort median 		7.09 70.7%
KLOTHO Anti-aging 0.54
bar=donor   line=cohort median 		0.66 36.9%
IRS2 Insulin/IGF-1 Signaling 5.70
bar=donor   line=cohort median 		5.59 61.7%
TP53 Tumor Suppression 2.29
bar=donor   line=cohort median 		2.72 26.6%
SHC1 Signal Transduction 3.79
bar=donor   line=cohort median 		3.95 23.1%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 14.3 1,213,183
2 B2M ENSG00000166710 protein_coding 13.8 854,321
3 ENSG00000258486 ENSG00000258486 13.6 732,476
4 ENSG00000265150 ENSG00000265150 13.3 609,971
5 S100A9 ENSG00000163220 protein_coding 13.2 542,520
6 MALAT1 ENSG00000251562 lncRNA 13.1 537,663
7 ALAS2 ENSG00000158578 protein_coding 13.1 520,281
8 AL355075.4 ENSG00000259001 lncRNA 12.7 402,046
9 NAMPT ENSG00000105835 protein_coding 12.3 309,367
10 HLA-E ENSG00000204592 protein_coding 12.3 309,180

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.7
bar=donor   line=cohort median 		11.8 11.8 39.4%
2 S100A9 protein_coding 13.2
bar=donor   line=cohort median 		13.1 13.1 55.1%
3 IL1B protein_coding 6.4
bar=donor   line=cohort median 		6.9 6.9 22.9%
4 CXCL8 protein_coding 8.6
bar=donor   line=cohort median 		7.6 7.6 85.3%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.3
bar=donor   line=cohort median 		4.0 4.0 60.6%
6 FCGR3B protein_coding 11.9
bar=donor   line=cohort median 		11.3 11.3 89.4%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.8
bar=donor   line=cohort median 		10.9 10.9 45.5%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.7
bar=donor   line=cohort median 		5.3 5.3 87.3%
9 CD3E protein_coding 2.7
bar=donor   line=cohort median 		2.6 2.6 53.1%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.3
bar=donor   line=cohort median 		6.3 6.3 49.0%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.8
bar=donor   line=cohort median 		3.4 3.4 66.8%
12 GNLY protein_coding 5.0
bar=donor   line=cohort median 		4.9 4.9 59.9%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 10.6
bar=donor   line=cohort median 		6.6 6.6 90.1%
14 HBA1 protein_coding 8.1
bar=donor   line=cohort median 		2.6 2.6 98.3%
15 HBA2 protein_coding 11.1
bar=donor   line=cohort median 		5.6 5.6 95.5%
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