GSM5528503

Dataset: gse182409 • Sample: T007 • Status: Pregnancy-stage cohort

Quality Control Metrics

62,549,834 Total counts Group median: 70,855,220 • 26.4%ile (≈ Median)
31,748 Detected genes Group median: 31,576 • 54.5%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 12.0%ile (↓ Low)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

44.6Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.79
bar=donor   line=cohort median
9.31 83.8%
CETP Lipid Metabolism 2.37
bar=donor   line=cohort median
1.18 96.9%
SIRT6 Sirtuin Family 2.01
bar=donor   line=cohort median
2.22 23.1%
SIRT1 Sirtuin Family 5.38
bar=donor   line=cohort median
5.50 21.0%
SIRT3 Sirtuin Family 2.36
bar=donor   line=cohort median
2.33 54.8%
IGF1R Insulin/IGF-1 Signaling 6.33
bar=donor   line=cohort median
7.09 3.1%
KLOTHO Anti-aging 1.35
bar=donor   line=cohort median
0.66 87.9%
IRS2 Insulin/IGF-1 Signaling 4.71
bar=donor   line=cohort median
5.59 3.8%
TP53 Tumor Suppression 2.35
bar=donor   line=cohort median
2.72 30.0%
SHC1 Signal Transduction 3.87
bar=donor   line=cohort median
3.95 41.7%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.2 2,163,559
2 ENSG00000258486 ENSG00000258486 15.1 1,966,223
3 7SK ENSG00000202198 misc_RNA 14.9 1,796,818
4 B2M ENSG00000166710 protein_coding 13.6 731,853
5 S100A9 ENSG00000163220 protein_coding 13.4 602,249
6 MALAT1 ENSG00000251562 lncRNA 13.0 459,461
7 AL355075.4 ENSG00000259001 lncRNA 12.9 426,308
8 EEF1A1 ENSG00000156508 protein_coding 12.8 420,286
9 BNIP3L ENSG00000104765 protein_coding 12.8 396,929
10 NAMPT ENSG00000105835 protein_coding 12.4 305,405

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.1
bar=donor   line=cohort median
11.8 11.8 72.3%
2 S100A9 protein_coding 13.4
bar=donor   line=cohort median
13.1 13.1 77.7%
3 IL1B protein_coding 6.3
bar=donor   line=cohort median
6.9 6.9 18.2%
4 CXCL8 protein_coding 7.1
bar=donor   line=cohort median
7.6 7.6 37.3%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.0
bar=donor   line=cohort median
4.0 4.0 51.0%
6 FCGR3B protein_coding 10.8
bar=donor   line=cohort median
11.3 11.3 14.7%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.4
bar=donor   line=cohort median
10.9 10.9 84.6%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 6.3
bar=donor   line=cohort median
5.3 5.3 99.0%
9 CD3E protein_coding 2.8
bar=donor   line=cohort median
2.6 2.6 59.2%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 7.0
bar=donor   line=cohort median
6.3 6.3 94.9%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.1
bar=donor   line=cohort median
3.4 3.4 35.3%
12 GNLY protein_coding 4.9
bar=donor   line=cohort median
4.9 4.9 48.3%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 5.3
bar=donor   line=cohort median
6.6 6.6 19.5%
14 HBA1 protein_coding -0.2
bar=donor   line=cohort median
2.6 2.6 19.5%
15 HBA2 protein_coding 2.9
bar=donor   line=cohort median
5.6 5.6 14.0%