GSM5528504

Dataset: gse182409 • Sample: T008 • Status: Pregnancy-stage cohort
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Quality Control Metrics

66,044,283 Total counts Group median: 70,855,220 • 37.3%ile (≈ Median)
27,031 Detected genes Group median: 31,576 • 6.5%ile (↓ Low)
0 Mitochondrial fraction (%) Group median: 0 • 26.4%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

25.5Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.04
bar=donor   line=cohort median 		9.31 27.2%
CETP Lipid Metabolism 0.82
bar=donor   line=cohort median 		1.18 22.4%
SIRT6 Sirtuin Family 1.81
bar=donor   line=cohort median 		2.22 7.2%
SIRT1 Sirtuin Family 5.80
bar=donor   line=cohort median 		5.50 93.5%
SIRT3 Sirtuin Family 2.39
bar=donor   line=cohort median 		2.33 58.3%
IGF1R Insulin/IGF-1 Signaling 6.21
bar=donor   line=cohort median 		7.09 1.0%
KLOTHO Anti-aging -0.10
bar=donor   line=cohort median 		0.66 8.6%
IRS2 Insulin/IGF-1 Signaling 4.78
bar=donor   line=cohort median 		5.59 7.2%
TP53 Tumor Suppression 2.13
bar=donor   line=cohort median 		2.72 15.5%
SHC1 Signal Transduction 3.71
bar=donor   line=cohort median 		3.95 13.5%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 14.2 1,182,144
2 ENSG00000265150 ENSG00000265150 13.8 854,600
3 ENSG00000258486 ENSG00000258486 13.7 836,944
4 B2M ENSG00000166710 protein_coding 13.5 691,682
5 ALAS2 ENSG00000158578 protein_coding 13.4 661,542
6 MALAT1 ENSG00000251562 lncRNA 13.4 640,683
7 S100A9 ENSG00000163220 protein_coding 13.2 590,562
8 AL355075.4 ENSG00000259001 lncRNA 12.9 450,642
9 EPB41 ENSG00000159023 protein_coding 12.6 374,207
10 SLC25A37 ENSG00000147454 protein_coding 12.3 309,405

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.2
bar=donor   line=cohort median 		11.8 11.8 83.2%
2 S100A9 protein_coding 13.2
bar=donor   line=cohort median 		13.1 13.1 66.1%
3 IL1B protein_coding 7.1
bar=donor   line=cohort median 		6.9 6.9 72.3%
4 CXCL8 protein_coding 6.8
bar=donor   line=cohort median 		7.6 7.6 26.4%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 6.5
bar=donor   line=cohort median 		4.0 4.0 98.3%
6 FCGR3B protein_coding 11.7
bar=donor   line=cohort median 		11.3 11.3 76.4%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.9
bar=donor   line=cohort median 		10.9 10.9 52.4%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.2
bar=donor   line=cohort median 		5.3 5.3 40.8%
9 CD3E protein_coding 2.1
bar=donor   line=cohort median 		2.6 2.6 26.4%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.4
bar=donor   line=cohort median 		6.3 6.3 62.7%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.8
bar=donor   line=cohort median 		3.4 3.4 70.2%
12 GNLY protein_coding 4.6
bar=donor   line=cohort median 		4.9 4.9 31.8%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 5.9
bar=donor   line=cohort median 		6.6 6.6 33.2%
14 HBA1 protein_coding 3.7
bar=donor   line=cohort median 		2.6 2.6 61.3%
15 HBA2 protein_coding 6.6
bar=donor   line=cohort median 		5.6 5.6 61.3%
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