GSM5528505

Dataset: gse182409 • Sample: T009 • Status: Pregnancy-stage cohort
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Quality Control Metrics

73,323,114 Total counts Group median: 70,855,220 • 56.5%ile (≈ Median)
33,240 Detected genes Group median: 31,576 • 86.6%ile (↑ High)
0 Mitochondrial fraction (%) Group median: 0 • 77.1%ile (↑ High)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

49.3Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.18
bar=donor   line=cohort median 		9.31 40.3%
CETP Lipid Metabolism 1.72
bar=donor   line=cohort median 		1.18 82.4%
SIRT6 Sirtuin Family 2.32
bar=donor   line=cohort median 		2.22 67.2%
SIRT1 Sirtuin Family 5.63
bar=donor   line=cohort median 		5.50 74.8%
SIRT3 Sirtuin Family 2.24
bar=donor   line=cohort median 		2.33 35.5%
IGF1R Insulin/IGF-1 Signaling 6.90
bar=donor   line=cohort median 		7.09 32.1%
KLOTHO Anti-aging 1.20
bar=donor   line=cohort median 		0.66 83.8%
IRS2 Insulin/IGF-1 Signaling 5.06
bar=donor   line=cohort median 		5.59 13.5%
TP53 Tumor Suppression 2.04
bar=donor   line=cohort median 		2.72 11.4%
SHC1 Signal Transduction 3.96
bar=donor   line=cohort median 		3.95 52.1%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 14.9 2,247,967
2 ENSG00000258486 ENSG00000258486 14.8 2,038,992
3 7SK ENSG00000202198 misc_RNA 13.7 968,407
4 MALAT1 ENSG00000251562 lncRNA 13.3 756,826
5 ALAS2 ENSG00000158578 protein_coding 12.8 539,054
6 B2M ENSG00000166710 protein_coding 12.7 500,467
7 S100A9 ENSG00000163220 protein_coding 12.6 455,409
8 AL355075.4 ENSG00000259001 lncRNA 12.5 424,459
9 SLC25A37 ENSG00000147454 protein_coding 12.4 395,097
10 BNIP3L ENSG00000104765 protein_coding 12.4 394,112

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.0
bar=donor   line=cohort median 		11.8 11.8 4.5%
2 S100A9 protein_coding 12.6
bar=donor   line=cohort median 		13.1 13.1 16.8%
3 IL1B protein_coding 6.9
bar=donor   line=cohort median 		6.9 6.9 49.0%
4 CXCL8 protein_coding 6.3
bar=donor   line=cohort median 		7.6 7.6 14.7%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 2.9
bar=donor   line=cohort median 		4.0 4.0 21.6%
6 FCGR3B protein_coding 11.6
bar=donor   line=cohort median 		11.3 11.3 71.6%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 9.5
bar=donor   line=cohort median 		10.9 10.9 0.3%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.5
bar=donor   line=cohort median 		5.3 5.3 67.5%
9 CD3E protein_coding 4.0
bar=donor   line=cohort median 		2.6 2.6 97.6%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.8
bar=donor   line=cohort median 		6.3 6.3 19.5%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 5.0
bar=donor   line=cohort median 		3.4 3.4 96.9%
12 GNLY protein_coding 6.1
bar=donor   line=cohort median 		4.9 4.9 96.9%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 8.5
bar=donor   line=cohort median 		6.6 6.6 73.6%
14 HBA1 protein_coding 3.0
bar=donor   line=cohort median 		2.6 2.6 55.8%
15 HBA2 protein_coding 8.0
bar=donor   line=cohort median 		5.6 5.6 75.0%
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