GSM5528506

Dataset: gse182409 • Sample: T010 • Status: Pregnancy-stage cohort
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Quality Control Metrics

64,443,162 Total counts Group median: 70,855,220 • 32.5%ile (≈ Median)
32,256 Detected genes Group median: 31,576 • 66.1%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 28.4%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

63.6Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.10
bar=donor   line=cohort median 		9.31 33.5%
CETP Lipid Metabolism 1.72
bar=donor   line=cohort median 		1.18 81.7%
SIRT6 Sirtuin Family 2.49
bar=donor   line=cohort median 		2.22 87.2%
SIRT1 Sirtuin Family 5.40
bar=donor   line=cohort median 		5.50 24.5%
SIRT3 Sirtuin Family 2.42
bar=donor   line=cohort median 		2.33 63.8%
IGF1R Insulin/IGF-1 Signaling 7.16
bar=donor   line=cohort median 		7.09 56.9%
KLOTHO Anti-aging 0.62
bar=donor   line=cohort median 		0.66 45.9%
IRS2 Insulin/IGF-1 Signaling 5.63
bar=donor   line=cohort median 		5.59 54.8%
TP53 Tumor Suppression 3.62
bar=donor   line=cohort median 		2.72 92.8%
SHC1 Signal Transduction 4.34
bar=donor   line=cohort median 		3.95 94.8%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.3 2,329,556
2 ENSG00000258486 ENSG00000258486 15.2 2,115,543
3 7SK ENSG00000202198 misc_RNA 14.7 1,495,353
4 AL355075.4 ENSG00000259001 lncRNA 13.6 726,921
5 B2M ENSG00000166710 protein_coding 13.4 633,038
6 ALAS2 ENSG00000158578 protein_coding 13.4 627,757
7 MALAT1 ENSG00000251562 lncRNA 13.4 604,296
8 S100A9 ENSG00000163220 protein_coding 13.2 559,854
9 BNIP3L ENSG00000104765 protein_coding 12.8 418,198
10 SLC25A37 ENSG00000147454 protein_coding 12.7 377,757

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.8
bar=donor   line=cohort median 		11.8 11.8 51.7%
2 S100A9 protein_coding 13.2
bar=donor   line=cohort median 		13.1 13.1 66.8%
3 IL1B protein_coding 7.2
bar=donor   line=cohort median 		6.9 6.9 77.1%
4 CXCL8 protein_coding 6.9
bar=donor   line=cohort median 		7.6 7.6 31.2%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 2.3
bar=donor   line=cohort median 		4.0 4.0 8.6%
6 FCGR3B protein_coding 11.8
bar=donor   line=cohort median 		11.3 11.3 81.8%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.9
bar=donor   line=cohort median 		10.9 10.9 46.2%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.1
bar=donor   line=cohort median 		5.3 5.3 31.8%
9 CD3E protein_coding 3.1
bar=donor   line=cohort median 		2.6 2.6 70.9%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.0
bar=donor   line=cohort median 		6.3 6.3 30.5%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 2.2
bar=donor   line=cohort median 		3.4 3.4 3.1%
12 GNLY protein_coding 4.3
bar=donor   line=cohort median 		4.9 4.9 16.8%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 9.0
bar=donor   line=cohort median 		6.6 6.6 78.4%
14 HBA1 protein_coding 3.1
bar=donor   line=cohort median 		2.6 2.6 57.9%
15 HBA2 protein_coding 5.6
bar=donor   line=cohort median 		5.6 5.6 48.3%
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