GSM5528507

Dataset: gse182409 • Sample: T011 • Status: Pregnancy-stage cohort
◂ Prev All Donors Next ▸

Quality Control Metrics

87,127,854 Total counts Group median: 70,855,220 • 86.6%ile (↑ High)
32,800 Detected genes Group median: 31,576 • 79.8%ile (↑ High)
0 Mitochondrial fraction (%) Group median: 0 • 9.9%ile (↓ Low)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

29.3Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.36
bar=donor   line=cohort median 		9.31 52.1%
CETP Lipid Metabolism 1.09
bar=donor   line=cohort median 		1.18 41.7%
SIRT6 Sirtuin Family 1.85
bar=donor   line=cohort median 		2.22 12.8%
SIRT1 Sirtuin Family 5.38
bar=donor   line=cohort median 		5.50 22.4%
SIRT3 Sirtuin Family 2.09
bar=donor   line=cohort median 		2.33 16.9%
IGF1R Insulin/IGF-1 Signaling 7.01
bar=donor   line=cohort median 		7.09 41.0%
KLOTHO Anti-aging 0.47
bar=donor   line=cohort median 		0.66 31.4%
IRS2 Insulin/IGF-1 Signaling 5.20
bar=donor   line=cohort median 		5.59 21.7%
TP53 Tumor Suppression 2.59
bar=donor   line=cohort median 		2.72 44.5%
SHC1 Signal Transduction 3.65
bar=donor   line=cohort median 		3.95 8.6%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 14.6 1,991,032
2 B2M ENSG00000166710 protein_coding 14.1 1,419,266
3 ENSG00000258486 ENSG00000258486 13.9 1,253,924
4 ENSG00000265150 ENSG00000265150 13.9 1,205,743
5 S100A9 ENSG00000163220 protein_coding 13.5 895,895
6 AL355075.4 ENSG00000259001 lncRNA 13.0 661,473
7 MALAT1 ENSG00000251562 lncRNA 13.0 647,188
8 ALAS2 ENSG00000158578 protein_coding 12.9 606,509
9 NAMPT ENSG00000105835 protein_coding 12.6 500,577
10 SOD2 ENSG00000112096 protein_coding 12.5 465,104

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.2
bar=donor   line=cohort median 		11.8 11.8 83.9%
2 S100A9 protein_coding 13.5
bar=donor   line=cohort median 		13.1 13.1 81.8%
3 IL1B protein_coding 8.0
bar=donor   line=cohort median 		6.9 6.9 99.0%
4 CXCL8 protein_coding 6.7
bar=donor   line=cohort median 		7.6 7.6 22.3%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 2.6
bar=donor   line=cohort median 		4.0 4.0 15.4%
6 FCGR3B protein_coding 12.1
bar=donor   line=cohort median 		11.3 11.3 94.2%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.9
bar=donor   line=cohort median 		10.9 10.9 99.0%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.1
bar=donor   line=cohort median 		5.3 5.3 27.7%
9 CD3E protein_coding 1.3
bar=donor   line=cohort median 		2.6 2.6 3.1%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.1
bar=donor   line=cohort median 		6.3 6.3 38.7%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 2.4
bar=donor   line=cohort median 		3.4 3.4 7.2%
12 GNLY protein_coding 4.4
bar=donor   line=cohort median 		4.9 4.9 23.6%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 8.7
bar=donor   line=cohort median 		6.6 6.6 74.3%
14 HBA1 protein_coding 2.7
bar=donor   line=cohort median 		2.6 2.6 51.0%
15 HBA2 protein_coding 5.4
bar=donor   line=cohort median 		5.6 5.6 45.5%
◂ Previous Donor Back to Donor List Next Donor ▸