GSM5528508

Dataset: gse182409 • Sample: T012 • Status: Pregnancy-stage cohort
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Quality Control Metrics

71,386,155 Total counts Group median: 70,855,220 • 52.4%ile (≈ Median)
29,284 Detected genes Group median: 31,576 • 28.4%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 16.8%ile (↓ Low)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

33.9Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.70
bar=donor   line=cohort median 		9.31 9.3%
CETP Lipid Metabolism 2.02
bar=donor   line=cohort median 		1.18 90.0%
SIRT6 Sirtuin Family 1.72
bar=donor   line=cohort median 		2.22 3.1%
SIRT1 Sirtuin Family 5.60
bar=donor   line=cohort median 		5.50 68.6%
SIRT3 Sirtuin Family 2.13
bar=donor   line=cohort median 		2.33 21.7%
IGF1R Insulin/IGF-1 Signaling 6.09
bar=donor   line=cohort median 		7.09 0.3%
KLOTHO Anti-aging 0.72
bar=donor   line=cohort median 		0.66 55.5%
IRS2 Insulin/IGF-1 Signaling 3.83
bar=donor   line=cohort median 		5.59 0.3%
TP53 Tumor Suppression 2.20
bar=donor   line=cohort median 		2.72 19.0%
SHC1 Signal Transduction 4.10
bar=donor   line=cohort median 		3.95 71.4%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 14.7 1,864,450
2 ENSG00000258486 ENSG00000258486 14.6 1,721,703
3 7SK ENSG00000202198 misc_RNA 14.0 1,161,187
4 MALAT1 ENSG00000251562 lncRNA 13.5 805,860
5 B2M ENSG00000166710 protein_coding 13.2 666,514
6 AL355075.4 ENSG00000259001 lncRNA 12.9 566,019
7 BNIP3L ENSG00000104765 protein_coding 12.7 486,258
8 ALAS2 ENSG00000158578 protein_coding 12.7 473,657
9 S100A9 ENSG00000163220 protein_coding 12.7 464,283
10 EEF1A1 ENSG00000156508 protein_coding 12.3 372,942

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.3
bar=donor   line=cohort median 		11.8 11.8 18.2%
2 S100A9 protein_coding 12.7
bar=donor   line=cohort median 		13.1 13.1 18.8%
3 IL1B protein_coding 5.3
bar=donor   line=cohort median 		6.9 6.9 1.7%
4 CXCL8 protein_coding 6.0
bar=donor   line=cohort median 		7.6 7.6 9.9%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 1.8
bar=donor   line=cohort median 		4.0 4.0 3.1%
6 FCGR3B protein_coding 10.5
bar=donor   line=cohort median 		11.3 11.3 5.8%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.8
bar=donor   line=cohort median 		10.9 10.9 42.1%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.5
bar=donor   line=cohort median 		5.3 5.3 74.3%
9 CD3E protein_coding 2.1
bar=donor   line=cohort median 		2.6 2.6 25.0%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.6
bar=donor   line=cohort median 		6.3 6.3 8.6%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.1
bar=donor   line=cohort median 		3.4 3.4 31.8%
12 GNLY protein_coding 5.0
bar=donor   line=cohort median 		4.9 4.9 56.5%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 9.4
bar=donor   line=cohort median 		6.6 6.6 82.5%
14 HBA1 protein_coding 3.6
bar=donor   line=cohort median 		2.6 2.6 60.6%
15 HBA2 protein_coding 6.3
bar=donor   line=cohort median 		5.6 5.6 57.2%
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