GSM5528510

Dataset: gse182409 • Sample: T014 • Status: Pregnancy-stage cohort
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Quality Control Metrics

89,896,333 Total counts Group median: 70,855,220 • 90.8%ile (↑ High)
33,420 Detected genes Group median: 31,576 • 89.0%ile (↑ High)
0 Mitochondrial fraction (%) Group median: 0 • 64.0%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

43.5Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.35
bar=donor   line=cohort median 		9.31 51.4%
CETP Lipid Metabolism 0.77
bar=donor   line=cohort median 		1.18 19.7%
SIRT6 Sirtuin Family 2.44
bar=donor   line=cohort median 		2.22 81.0%
SIRT1 Sirtuin Family 5.48
bar=donor   line=cohort median 		5.50 43.1%
SIRT3 Sirtuin Family 2.07
bar=donor   line=cohort median 		2.33 15.5%
IGF1R Insulin/IGF-1 Signaling 7.07
bar=donor   line=cohort median 		7.09 49.3%
KLOTHO Anti-aging 0.54
bar=donor   line=cohort median 		0.66 36.2%
IRS2 Insulin/IGF-1 Signaling 5.80
bar=donor   line=cohort median 		5.59 68.6%
TP53 Tumor Suppression 2.54
bar=donor   line=cohort median 		2.72 41.0%
SHC1 Signal Transduction 3.82
bar=donor   line=cohort median 		3.95 29.3%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.3 3,240,418
2 ENSG00000258486 ENSG00000258486 15.2 3,082,331
3 ALAS2 ENSG00000158578 protein_coding 14.1 1,419,154
4 7SK ENSG00000202198 misc_RNA 14.0 1,280,287
5 B2M ENSG00000166710 protein_coding 13.4 833,049
6 SLC25A37 ENSG00000147454 protein_coding 13.1 701,408
7 MALAT1 ENSG00000251562 lncRNA 13.1 696,716
8 EPB41 ENSG00000159023 protein_coding 12.8 550,458
9 S100A9 ENSG00000163220 protein_coding 12.7 545,172
10 AL355075.4 ENSG00000259001 lncRNA 12.7 533,094

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.2
bar=donor   line=cohort median 		11.8 11.8 14.7%
2 S100A9 protein_coding 12.7
bar=donor   line=cohort median 		13.1 13.1 25.0%
3 IL1B protein_coding 6.1
bar=donor   line=cohort median 		6.9 6.9 9.9%
4 CXCL8 protein_coding 6.1
bar=donor   line=cohort median 		7.6 7.6 11.3%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.5
bar=donor   line=cohort median 		4.0 4.0 35.3%
6 FCGR3B protein_coding 10.4
bar=donor   line=cohort median 		11.3 11.3 5.1%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.7
bar=donor   line=cohort median 		10.9 10.9 31.8%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.6
bar=donor   line=cohort median 		5.3 5.3 75.7%
9 CD3E protein_coding 2.8
bar=donor   line=cohort median 		2.6 2.6 57.2%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.2
bar=donor   line=cohort median 		6.3 6.3 42.8%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.4
bar=donor   line=cohort median 		3.4 3.4 48.3%
12 GNLY protein_coding 5.7
bar=donor   line=cohort median 		4.9 4.9 91.4%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 9.5
bar=donor   line=cohort median 		6.6 6.6 86.0%
14 HBA1 protein_coding 4.5
bar=donor   line=cohort median 		2.6 2.6 68.8%
15 HBA2 protein_coding 8.3
bar=donor   line=cohort median 		5.6 5.6 79.1%
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