GSM5528511

Dataset: gse182409 • Sample: T015 • Status: Pregnancy-stage cohort
◂ Prev All Donors Next ▸

Quality Control Metrics

75,771,829 Total counts Group median: 70,855,220 • 60.6%ile (≈ Median)
27,746 Detected genes Group median: 31,576 • 14.0%ile (↓ Low)
0 Mitochondrial fraction (%) Group median: 0 • 79.1%ile (↑ High)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

41.0Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.58
bar=donor   line=cohort median 		9.31 70.7%
CETP Lipid Metabolism 1.27
bar=donor   line=cohort median 		1.18 56.2%
SIRT6 Sirtuin Family 2.21
bar=donor   line=cohort median 		2.22 48.6%
SIRT1 Sirtuin Family 5.50
bar=donor   line=cohort median 		5.50 47.9%
SIRT3 Sirtuin Family 2.28
bar=donor   line=cohort median 		2.33 45.2%
IGF1R Insulin/IGF-1 Signaling 6.66
bar=donor   line=cohort median 		7.09 13.5%
KLOTHO Anti-aging 0.43
bar=donor   line=cohort median 		0.66 27.9%
IRS2 Insulin/IGF-1 Signaling 5.20
bar=donor   line=cohort median 		5.59 20.3%
TP53 Tumor Suppression 2.72
bar=donor   line=cohort median 		2.72 50.0%
SHC1 Signal Transduction 3.82
bar=donor   line=cohort median 		3.95 30.0%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 14.9 1,802,089
2 ENSG00000265150 ENSG00000265150 14.2 1,113,225
3 ENSG00000258486 ENSG00000258486 14.2 1,074,609
4 B2M ENSG00000166710 protein_coding 13.7 749,781
5 AL355075.4 ENSG00000259001 lncRNA 13.6 727,656
6 S100A9 ENSG00000163220 protein_coding 13.5 691,918
7 ALAS2 ENSG00000158578 protein_coding 13.2 539,520
8 MALAT1 ENSG00000251562 lncRNA 13.2 539,082
9 NAMPT ENSG00000105835 protein_coding 12.9 430,726
10 SORL1 ENSG00000137642 protein_coding 12.6 367,404

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.5
bar=donor   line=cohort median 		11.8 11.8 92.8%
2 S100A9 protein_coding 13.5
bar=donor   line=cohort median 		13.1 13.1 87.3%
3 IL1B protein_coding 7.8
bar=donor   line=cohort median 		6.9 6.9 97.6%
4 CXCL8 protein_coding 8.4
bar=donor   line=cohort median 		7.6 7.6 80.5%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.9
bar=donor   line=cohort median 		4.0 4.0 71.6%
6 FCGR3B protein_coding 11.7
bar=donor   line=cohort median 		11.3 11.3 74.3%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.0
bar=donor   line=cohort median 		10.9 10.9 53.8%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.6
bar=donor   line=cohort median 		5.3 5.3 77.7%
9 CD3E protein_coding 1.5
bar=donor   line=cohort median 		2.6 2.6 8.6%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.8
bar=donor   line=cohort median 		6.3 6.3 18.2%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 4.0
bar=donor   line=cohort median 		3.4 3.4 75.7%
12 GNLY protein_coding 5.7
bar=donor   line=cohort median 		4.9 4.9 88.7%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 9.5
bar=donor   line=cohort median 		6.6 6.6 84.6%
14 HBA1 protein_coding 7.3
bar=donor   line=cohort median 		2.6 2.6 94.2%
15 HBA2 protein_coding 10.3
bar=donor   line=cohort median 		5.6 5.6 90.8%
◂ Previous Donor Back to Donor List Next Donor ▸