GSM5528513

Dataset: gse182409 • Sample: T017 • Status: Pregnancy-stage cohort
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Quality Control Metrics

83,697,874 Total counts Group median: 70,855,220 • 79.8%ile (↑ High)
29,515 Detected genes Group median: 31,576 • 31.2%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 51.7%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

61.9Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.16
bar=donor   line=cohort median 		9.31 39.7%
CETP Lipid Metabolism 1.54
bar=donor   line=cohort median 		1.18 72.1%
SIRT6 Sirtuin Family 2.70
bar=donor   line=cohort median 		2.22 96.2%
SIRT1 Sirtuin Family 5.65
bar=donor   line=cohort median 		5.50 80.3%
SIRT3 Sirtuin Family 1.86
bar=donor   line=cohort median 		2.33 2.4%
IGF1R Insulin/IGF-1 Signaling 7.11
bar=donor   line=cohort median 		7.09 53.5%
KLOTHO Anti-aging 1.42
bar=donor   line=cohort median 		0.66 92.8%
IRS2 Insulin/IGF-1 Signaling 5.59
bar=donor   line=cohort median 		5.59 50.7%
TP53 Tumor Suppression 2.42
bar=donor   line=cohort median 		2.72 34.1%
SHC1 Signal Transduction 4.48
bar=donor   line=cohort median 		3.95 96.9%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 14.4 1,750,145
2 S100A9 ENSG00000163220 protein_coding 13.8 1,157,226
3 B2M ENSG00000166710 protein_coding 13.4 881,566
4 MALAT1 ENSG00000251562 lncRNA 13.2 768,725
5 ALAS2 ENSG00000158578 protein_coding 12.9 638,553
6 AL355075.4 ENSG00000259001 lncRNA 12.9 633,505
7 ENSG00000258486 ENSG00000258486 12.8 600,580
8 ENSG00000265150 ENSG00000265150 12.8 591,293
9 NAMPT ENSG00000105835 protein_coding 12.7 545,982
10 S100A8 ENSG00000143546 protein_coding 12.5 490,497

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.5
bar=donor   line=cohort median 		11.8 11.8 94.2%
2 S100A9 protein_coding 13.8
bar=donor   line=cohort median 		13.1 13.1 94.9%
3 IL1B protein_coding 6.8
bar=donor   line=cohort median 		6.9 6.9 47.6%
4 CXCL8 protein_coding 7.8
bar=donor   line=cohort median 		7.6 7.6 58.6%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 5.0
bar=donor   line=cohort median 		4.0 4.0 76.4%
6 FCGR3B protein_coding 12.0
bar=donor   line=cohort median 		11.3 11.3 91.4%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.5
bar=donor   line=cohort median 		10.9 10.9 21.6%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.6
bar=donor   line=cohort median 		5.3 5.3 78.4%
9 CD3E protein_coding 2.7
bar=donor   line=cohort median 		2.6 2.6 54.5%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.3
bar=donor   line=cohort median 		6.3 6.3 51.0%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.6
bar=donor   line=cohort median 		3.4 3.4 59.9%
12 GNLY protein_coding 4.8
bar=donor   line=cohort median 		4.9 4.9 46.9%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 6.7
bar=donor   line=cohort median 		6.6 6.6 51.0%
14 HBA1 protein_coding 2.2
bar=donor   line=cohort median 		2.6 2.6 45.5%
15 HBA2 protein_coding 5.9
bar=donor   line=cohort median 		5.6 5.6 53.1%
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