GSM5528516

Dataset: gse182409 • Sample: T020 • Status: Pregnancy-stage cohort
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Quality Control Metrics

71,958,759 Total counts Group median: 70,855,220 • 54.5%ile (≈ Median)
24,333 Detected genes Group median: 31,576 • 0.3%ile (↓ Low)
0 Mitochondrial fraction (%) Group median: 0 • 1.7%ile (↓ Low)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

57.1Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.22
bar=donor   line=cohort median 		9.31 44.5%
CETP Lipid Metabolism 1.15
bar=donor   line=cohort median 		1.18 45.9%
SIRT6 Sirtuin Family 2.31
bar=donor   line=cohort median 		2.22 65.9%
SIRT1 Sirtuin Family 5.48
bar=donor   line=cohort median 		5.50 43.8%
SIRT3 Sirtuin Family 1.97
bar=donor   line=cohort median 		2.33 5.9%
IGF1R Insulin/IGF-1 Signaling 7.39
bar=donor   line=cohort median 		7.09 81.7%
KLOTHO Anti-aging 1.36
bar=donor   line=cohort median 		0.66 88.6%
IRS2 Insulin/IGF-1 Signaling 5.97
bar=donor   line=cohort median 		5.59 84.5%
TP53 Tumor Suppression 2.78
bar=donor   line=cohort median 		2.72 56.2%
SHC1 Signal Transduction 3.98
bar=donor   line=cohort median 		3.95 54.1%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 15.0 2,060,544
2 ENSG00000265150 ENSG00000265150 14.3 1,258,746
3 ENSG00000258486 ENSG00000258486 14.3 1,249,627
4 AL355075.4 ENSG00000259001 lncRNA 13.9 958,671
5 S100A9 ENSG00000163220 protein_coding 13.9 925,078
6 B2M ENSG00000166710 protein_coding 13.8 849,911
7 MALAT1 ENSG00000251562 lncRNA 13.1 532,341
8 ALAS2 ENSG00000158578 protein_coding 12.9 473,913
9 S100A8 ENSG00000143546 protein_coding 12.7 400,567
10 NAMPT ENSG00000105835 protein_coding 12.6 378,637

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.7
bar=donor   line=cohort median 		11.8 11.8 97.6%
2 S100A9 protein_coding 13.9
bar=donor   line=cohort median 		13.1 13.1 99.0%
3 IL1B protein_coding 7.0
bar=donor   line=cohort median 		6.9 6.9 66.1%
4 CXCL8 protein_coding 8.2
bar=donor   line=cohort median 		7.6 7.6 70.9%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 5.2
bar=donor   line=cohort median 		4.0 4.0 79.8%
6 FCGR3B protein_coding 11.3
bar=donor   line=cohort median 		11.3 11.3 46.9%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.0
bar=donor   line=cohort median 		10.9 10.9 59.9%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.8
bar=donor   line=cohort median 		5.3 5.3 90.8%
9 CD3E protein_coding 2.3
bar=donor   line=cohort median 		2.6 2.6 36.0%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.3
bar=donor   line=cohort median 		6.3 6.3 51.7%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.7
bar=donor   line=cohort median 		3.4 3.4 63.4%
12 GNLY protein_coding 6.1
bar=donor   line=cohort median 		4.9 4.9 95.5%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 8.2
bar=donor   line=cohort median 		6.6 6.6 71.6%
14 HBA1 protein_coding 2.6
bar=donor   line=cohort median 		2.6 2.6 49.0%
15 HBA2 protein_coding 4.7
bar=donor   line=cohort median 		5.6 5.6 39.4%
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