GSM5528517

Dataset: gse182409 • Sample: T021 • Status: Pregnancy-stage cohort
◂ Prev All Donors Next ▸

Quality Control Metrics

62,457,354 Total counts Group median: 70,855,220 • 25.7%ile (≈ Median)
26,543 Detected genes Group median: 31,576 • 4.5%ile (↓ Low)
0 Mitochondrial fraction (%) Group median: 0 • 9.2%ile (↓ Low)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

37.6Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.24
bar=donor   line=cohort median 		9.31 47.9%
CETP Lipid Metabolism 1.39
bar=donor   line=cohort median 		1.18 66.6%
SIRT6 Sirtuin Family 2.55
bar=donor   line=cohort median 		2.22 90.7%
SIRT1 Sirtuin Family 5.31
bar=donor   line=cohort median 		5.50 9.3%
SIRT3 Sirtuin Family 2.07
bar=donor   line=cohort median 		2.33 14.8%
IGF1R Insulin/IGF-1 Signaling 7.22
bar=donor   line=cohort median 		7.09 67.2%
KLOTHO Anti-aging 0.07
bar=donor   line=cohort median 		0.66 15.5%
IRS2 Insulin/IGF-1 Signaling 4.83
bar=donor   line=cohort median 		5.59 7.9%
TP53 Tumor Suppression 1.84
bar=donor   line=cohort median 		2.72 4.5%
SHC1 Signal Transduction 3.96
bar=donor   line=cohort median 		3.95 51.4%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 14.8 1,454,280
2 ENSG00000258486 ENSG00000258486 14.6 1,311,496
3 ENSG00000265150 ENSG00000265150 14.6 1,270,853
4 ALAS2 ENSG00000158578 protein_coding 13.8 752,071
5 B2M ENSG00000166710 protein_coding 13.8 749,255
6 S100A9 ENSG00000163220 protein_coding 13.6 647,857
7 AL355075.4 ENSG00000259001 lncRNA 13.6 638,839
8 MALAT1 ENSG00000251562 lncRNA 13.0 413,190
9 NAMPT ENSG00000105835 protein_coding 12.8 366,926
10 HLA-B ENSG00000234745 protein_coding 12.5 306,691

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.4
bar=donor   line=cohort median 		11.8 11.8 89.4%
2 S100A9 protein_coding 13.6
bar=donor   line=cohort median 		13.1 13.1 90.8%
3 IL1B protein_coding 6.7
bar=donor   line=cohort median 		6.9 6.9 42.1%
4 CXCL8 protein_coding 6.7
bar=donor   line=cohort median 		7.6 7.6 20.9%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.9
bar=donor   line=cohort median 		4.0 4.0 72.9%
6 FCGR3B protein_coding 12.0
bar=donor   line=cohort median 		11.3 11.3 92.8%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.1
bar=donor   line=cohort median 		10.9 10.9 65.4%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.5
bar=donor   line=cohort median 		5.3 5.3 66.1%
9 CD3E protein_coding 1.7
bar=donor   line=cohort median 		2.6 2.6 11.3%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.6
bar=donor   line=cohort median 		6.3 6.3 73.6%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.2
bar=donor   line=cohort median 		3.4 3.4 36.6%
12 GNLY protein_coding 4.5
bar=donor   line=cohort median 		4.9 4.9 29.1%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 6.1
bar=donor   line=cohort median 		6.6 6.6 40.1%
14 HBA1 protein_coding 4.5
bar=donor   line=cohort median 		2.6 2.6 69.5%
15 HBA2 protein_coding 7.2
bar=donor   line=cohort median 		5.6 5.6 66.8%
◂ Previous Donor Back to Donor List Next Donor ▸