GSM5528519

Dataset: gse182409 • Sample: T023 • Status: Pregnancy-stage cohort
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Quality Control Metrics

76,468,950 Total counts Group median: 70,855,220 • 61.3%ile (≈ Median)
32,876 Detected genes Group median: 31,576 • 80.5%ile (↑ High)
0 Mitochondrial fraction (%) Group median: 0 • 85.3%ile (↑ High)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

43.0Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.89
bar=donor   line=cohort median 		9.31 17.6%
CETP Lipid Metabolism 0.38
bar=donor   line=cohort median 		1.18 7.2%
SIRT6 Sirtuin Family 2.54
bar=donor   line=cohort median 		2.22 90.0%
SIRT1 Sirtuin Family 5.89
bar=donor   line=cohort median 		5.50 97.6%
SIRT3 Sirtuin Family 2.37
bar=donor   line=cohort median 		2.33 56.2%
IGF1R Insulin/IGF-1 Signaling 6.69
bar=donor   line=cohort median 		7.09 15.5%
KLOTHO Anti-aging 1.59
bar=donor   line=cohort median 		0.66 96.9%
IRS2 Insulin/IGF-1 Signaling 5.20
bar=donor   line=cohort median 		5.59 19.7%
TP53 Tumor Suppression 1.97
bar=donor   line=cohort median 		2.72 9.3%
SHC1 Signal Transduction 3.79
bar=donor   line=cohort median 		3.95 20.3%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.4 2,666,290
2 ENSG00000258486 ENSG00000258486 15.0 2,007,361
3 7SK ENSG00000202198 misc_RNA 14.5 1,506,834
4 HBB ENSG00000244734 protein_coding 13.8 901,365
5 MALAT1 ENSG00000251562 lncRNA 13.7 864,235
6 S100A9 ENSG00000163220 protein_coding 13.5 725,358
7 AL355075.4 ENSG00000259001 lncRNA 13.2 576,418
8 B2M ENSG00000166710 protein_coding 13.1 539,116
9 ALAS2 ENSG00000158578 protein_coding 12.6 404,141
10 NAMPT ENSG00000105835 protein_coding 12.5 357,549

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.1
bar=donor   line=cohort median 		11.8 11.8 76.4%
2 S100A9 protein_coding 13.5
bar=donor   line=cohort median 		13.1 13.1 84.6%
3 IL1B protein_coding 7.4
bar=donor   line=cohort median 		6.9 6.9 86.6%
4 CXCL8 protein_coding 5.3
bar=donor   line=cohort median 		7.6 7.6 3.1%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.1
bar=donor   line=cohort median 		4.0 4.0 52.4%
6 FCGR3B protein_coding 11.7
bar=donor   line=cohort median 		11.3 11.3 72.9%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.5
bar=donor   line=cohort median 		10.9 10.9 20.9%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 4.9
bar=donor   line=cohort median 		5.3 5.3 10.6%
9 CD3E protein_coding 3.1
bar=donor   line=cohort median 		2.6 2.6 72.9%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.8
bar=donor   line=cohort median 		6.3 6.3 20.2%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 4.2
bar=donor   line=cohort median 		3.4 3.4 83.9%
12 GNLY protein_coding 4.5
bar=donor   line=cohort median 		4.9 4.9 28.4%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 13.8
bar=donor   line=cohort median 		6.6 6.6 99.7%
14 HBA1 protein_coding 8.0
bar=donor   line=cohort median 		2.6 2.6 96.9%
15 HBA2 protein_coding 12.2
bar=donor   line=cohort median 		5.6 5.6 99.7%
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