GSM5528521

Dataset: gse182409 • Sample: T025 • Status: Pregnancy-stage cohort
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Quality Control Metrics

63,074,793 Total counts Group median: 70,855,220 • 28.4%ile (≈ Median)
31,572 Detected genes Group median: 31,576 • 49.7%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 16.1%ile (↓ Low)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

73.0Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.15
bar=donor   line=cohort median 		9.31 37.6%
CETP Lipid Metabolism 1.60
bar=donor   line=cohort median 		1.18 74.8%
SIRT6 Sirtuin Family 2.59
bar=donor   line=cohort median 		2.22 91.4%
SIRT1 Sirtuin Family 5.30
bar=donor   line=cohort median 		5.50 7.2%
SIRT3 Sirtuin Family 2.53
bar=donor   line=cohort median 		2.33 79.7%
IGF1R Insulin/IGF-1 Signaling 7.61
bar=donor   line=cohort median 		7.09 94.1%
KLOTHO Anti-aging 1.61
bar=donor   line=cohort median 		0.66 97.6%
IRS2 Insulin/IGF-1 Signaling 5.88
bar=donor   line=cohort median 		5.59 76.9%
TP53 Tumor Suppression 3.34
bar=donor   line=cohort median 		2.72 86.6%
SHC1 Signal Transduction 4.21
bar=donor   line=cohort median 		3.95 83.8%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000258486 ENSG00000258486 15.8 2,983,220
2 ENSG00000265150 ENSG00000265150 15.7 2,934,438
3 7SK ENSG00000202198 misc_RNA 14.9 1,612,432
4 AL355075.4 ENSG00000259001 lncRNA 13.8 755,001
5 MALAT1 ENSG00000251562 lncRNA 13.6 666,096
6 B2M ENSG00000166710 protein_coding 13.4 597,849
7 S100A9 ENSG00000163220 protein_coding 13.2 515,760
8 NAMPT ENSG00000105835 protein_coding 13.0 447,307
9 BNIP3L ENSG00000104765 protein_coding 12.9 404,134
10 ALAS2 ENSG00000158578 protein_coding 12.2 261,557

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.9
bar=donor   line=cohort median 		11.8 11.8 57.9%
2 S100A9 protein_coding 13.2
bar=donor   line=cohort median 		13.1 13.1 64.7%
3 IL1B protein_coding 6.6
bar=donor   line=cohort median 		6.9 6.9 33.9%
4 CXCL8 protein_coding 6.8
bar=donor   line=cohort median 		7.6 7.6 24.3%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 1.9
bar=donor   line=cohort median 		4.0 4.0 3.8%
6 FCGR3B protein_coding 11.3
bar=donor   line=cohort median 		11.3 11.3 51.7%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.1
bar=donor   line=cohort median 		10.9 10.9 9.2%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.1
bar=donor   line=cohort median 		5.3 5.3 29.8%
9 CD3E protein_coding 2.6
bar=donor   line=cohort median 		2.6 2.6 49.0%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.2
bar=donor   line=cohort median 		6.3 6.3 46.9%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 2.9
bar=donor   line=cohort median 		3.4 3.4 19.5%
12 GNLY protein_coding 4.9
bar=donor   line=cohort median 		4.9 4.9 49.0%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 7.7
bar=donor   line=cohort median 		6.6 6.6 62.0%
14 HBA1 protein_coding 1.8
bar=donor   line=cohort median 		2.6 2.6 40.1%
15 HBA2 protein_coding 4.8
bar=donor   line=cohort median 		5.6 5.6 40.8%
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