GSM5528523

Dataset: gse182409 • Sample: T027 • Status: Pregnancy-stage cohort
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Quality Control Metrics

58,945,968 Total counts Group median: 70,855,220 • 20.9%ile (↓ Low)
29,123 Detected genes Group median: 31,576 • 27.1%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 5.1%ile (↓ Low)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

44.2Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.09
bar=donor   line=cohort median 		9.31 32.8%
CETP Lipid Metabolism 1.37
bar=donor   line=cohort median 		1.18 65.2%
SIRT6 Sirtuin Family 1.93
bar=donor   line=cohort median 		2.22 16.2%
SIRT1 Sirtuin Family 5.63
bar=donor   line=cohort median 		5.50 74.1%
SIRT3 Sirtuin Family 2.25
bar=donor   line=cohort median 		2.33 39.0%
IGF1R Insulin/IGF-1 Signaling 7.16
bar=donor   line=cohort median 		7.09 56.2%
KLOTHO Anti-aging 0.61
bar=donor   line=cohort median 		0.66 45.2%
IRS2 Insulin/IGF-1 Signaling 5.78
bar=donor   line=cohort median 		5.59 65.9%
TP53 Tumor Suppression 2.49
bar=donor   line=cohort median 		2.72 38.3%
SHC1 Signal Transduction 3.65
bar=donor   line=cohort median 		3.95 9.3%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000258486 ENSG00000258486 15.3 1,865,683
2 ENSG00000265150 ENSG00000265150 15.3 1,841,387
3 7SK ENSG00000202198 misc_RNA 14.5 1,030,348
4 ALAS2 ENSG00000158578 protein_coding 13.7 608,343
5 B2M ENSG00000166710 protein_coding 13.5 512,832
6 S100A9 ENSG00000163220 protein_coding 13.4 489,422
7 AL355075.4 ENSG00000259001 lncRNA 13.2 433,661
8 BNIP3L ENSG00000104765 protein_coding 13.2 419,033
9 MALAT1 ENSG00000251562 lncRNA 13.1 401,997
10 EPB41 ENSG00000159023 protein_coding 13.0 380,307

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.1
bar=donor   line=cohort median 		11.8 11.8 73.6%
2 S100A9 protein_coding 13.4
bar=donor   line=cohort median 		13.1 13.1 80.5%
3 IL1B protein_coding 7.3
bar=donor   line=cohort median 		6.9 6.9 79.8%
4 CXCL8 protein_coding 7.5
bar=donor   line=cohort median 		7.6 7.6 46.9%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.6
bar=donor   line=cohort median 		4.0 4.0 66.1%
6 FCGR3B protein_coding 12.1
bar=donor   line=cohort median 		11.3 11.3 94.9%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.3
bar=donor   line=cohort median 		10.9 10.9 79.8%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 4.7
bar=donor   line=cohort median 		5.3 5.3 5.8%
9 CD3E protein_coding 1.5
bar=donor   line=cohort median 		2.6 2.6 7.2%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.5
bar=donor   line=cohort median 		6.3 6.3 69.5%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 2.5
bar=donor   line=cohort median 		3.4 3.4 9.2%
12 GNLY protein_coding 4.0
bar=donor   line=cohort median 		4.9 4.9 11.3%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 7.7
bar=donor   line=cohort median 		6.6 6.6 64.7%
14 HBA1 protein_coding 5.7
bar=donor   line=cohort median 		2.6 2.6 82.5%
15 HBA2 protein_coding 8.6
bar=donor   line=cohort median 		5.6 5.6 81.2%
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