GSM5528525

Dataset: gse182409 • Sample: T029 • Status: Pregnancy-stage cohort
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Quality Control Metrics

56,472,396 Total counts Group median: 70,855,220 • 16.8%ile (↓ Low)
27,830 Detected genes Group median: 31,576 • 15.4%ile (↓ Low)
0 Mitochondrial fraction (%) Group median: 0 • 42.1%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

40.7Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.84
bar=donor   line=cohort median 		9.31 85.9%
CETP Lipid Metabolism 0.96
bar=donor   line=cohort median 		1.18 35.5%
SIRT6 Sirtuin Family 2.11
bar=donor   line=cohort median 		2.22 37.6%
SIRT1 Sirtuin Family 5.53
bar=donor   line=cohort median 		5.50 58.3%
SIRT3 Sirtuin Family 1.95
bar=donor   line=cohort median 		2.33 5.2%
IGF1R Insulin/IGF-1 Signaling 6.88
bar=donor   line=cohort median 		7.09 29.3%
KLOTHO Anti-aging 1.51
bar=donor   line=cohort median 		0.66 96.2%
IRS2 Insulin/IGF-1 Signaling 5.54
bar=donor   line=cohort median 		5.59 42.4%
TP53 Tumor Suppression 1.35
bar=donor   line=cohort median 		2.72 0.3%
SHC1 Signal Transduction 3.73
bar=donor   line=cohort median 		3.95 16.2%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 14.5 1,222,322
2 ENSG00000265150 ENSG00000265150 14.3 1,051,522
3 ENSG00000258486 ENSG00000258486 14.3 1,028,824
4 AL355075.4 ENSG00000259001 lncRNA 13.4 556,211
5 B2M ENSG00000166710 protein_coding 13.3 533,494
6 S100A9 ENSG00000163220 protein_coding 13.3 526,166
7 MALAT1 ENSG00000251562 lncRNA 13.2 494,842
8 ALAS2 ENSG00000158578 protein_coding 13.1 450,604
9 BNIP3L ENSG00000104765 protein_coding 12.5 313,728
10 SLC25A37 ENSG00000147454 protein_coding 12.5 298,938

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.2
bar=donor   line=cohort median 		11.8 11.8 81.2%
2 S100A9 protein_coding 13.3
bar=donor   line=cohort median 		13.1 13.1 71.6%
3 IL1B protein_coding 7.1
bar=donor   line=cohort median 		6.9 6.9 70.9%
4 CXCL8 protein_coding 8.3
bar=donor   line=cohort median 		7.6 7.6 78.4%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.9
bar=donor   line=cohort median 		4.0 4.0 45.5%
6 FCGR3B protein_coding 11.2
bar=donor   line=cohort median 		11.3 11.3 38.7%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.4
bar=donor   line=cohort median 		10.9 10.9 83.9%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.7
bar=donor   line=cohort median 		5.3 5.3 83.2%
9 CD3E protein_coding 2.3
bar=donor   line=cohort median 		2.6 2.6 33.9%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.8
bar=donor   line=cohort median 		6.3 6.3 22.3%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 2.6
bar=donor   line=cohort median 		3.4 3.4 13.4%
12 GNLY protein_coding 3.9
bar=donor   line=cohort median 		4.9 4.9 5.8%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 7.4
bar=donor   line=cohort median 		6.6 6.6 57.9%
14 HBA1 protein_coding 4.6
bar=donor   line=cohort median 		2.6 2.6 70.2%
15 HBA2 protein_coding 6.8
bar=donor   line=cohort median 		5.6 5.6 63.4%
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