GSM5528527

Dataset: gse182409 • Sample: T031 • Status: Pregnancy-stage cohort
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Quality Control Metrics

104,615,778 Total counts Group median: 70,855,220 • 97.6%ile (↑ High)
33,033 Detected genes Group median: 31,576 • 81.8%ile (↑ High)
0 Mitochondrial fraction (%) Group median: 0 • 75.7%ile (↑ High)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

41.0Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.08
bar=donor   line=cohort median 		9.31 31.4%
CETP Lipid Metabolism 0.79
bar=donor   line=cohort median 		1.18 21.0%
SIRT6 Sirtuin Family 1.90
bar=donor   line=cohort median 		2.22 14.1%
SIRT1 Sirtuin Family 5.67
bar=donor   line=cohort median 		5.50 83.1%
SIRT3 Sirtuin Family 2.26
bar=donor   line=cohort median 		2.33 41.7%
IGF1R Insulin/IGF-1 Signaling 7.01
bar=donor   line=cohort median 		7.09 42.4%
KLOTHO Anti-aging 0.87
bar=donor   line=cohort median 		0.66 63.8%
IRS2 Insulin/IGF-1 Signaling 4.92
bar=donor   line=cohort median 		5.59 10.0%
TP53 Tumor Suppression 2.54
bar=donor   line=cohort median 		2.72 39.7%
SHC1 Signal Transduction 4.02
bar=donor   line=cohort median 		3.95 62.4%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 14.7 2,607,368
2 ENSG00000258486 ENSG00000258486 14.5 2,307,663
3 7SK ENSG00000202198 misc_RNA 14.1 1,813,319
4 B2M ENSG00000166710 protein_coding 13.3 991,951
5 S100A9 ENSG00000163220 protein_coding 13.1 916,735
6 MALAT1 ENSG00000251562 lncRNA 13.1 891,647
7 AL355075.4 ENSG00000259001 lncRNA 12.8 727,962
8 EEF1A1 ENSG00000156508 protein_coding 12.3 523,802
9 SOD2 ENSG00000112096 protein_coding 12.3 515,818
10 NAMPT ENSG00000105835 protein_coding 12.3 501,362

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.5
bar=donor   line=cohort median 		11.8 11.8 27.1%
2 S100A9 protein_coding 13.1
bar=donor   line=cohort median 		13.1 13.1 53.8%
3 IL1B protein_coding 6.8
bar=donor   line=cohort median 		6.9 6.9 46.9%
4 CXCL8 protein_coding 6.7
bar=donor   line=cohort median 		7.6 7.6 21.6%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.3
bar=donor   line=cohort median 		4.0 4.0 31.2%
6 FCGR3B protein_coding 11.4
bar=donor   line=cohort median 		11.3 11.3 53.1%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.4
bar=donor   line=cohort median 		10.9 10.9 88.0%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.4
bar=donor   line=cohort median 		5.3 5.3 60.6%
9 CD3E protein_coding 3.1
bar=donor   line=cohort median 		2.6 2.6 75.7%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.0
bar=donor   line=cohort median 		6.3 6.3 32.5%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.8
bar=donor   line=cohort median 		3.4 3.4 68.8%
12 GNLY protein_coding 4.9
bar=donor   line=cohort median 		4.9 4.9 52.4%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 4.6
bar=donor   line=cohort median 		6.6 6.6 6.5%
14 HBA1 protein_coding -0.6
bar=donor   line=cohort median 		2.6 2.6 10.6%
15 HBA2 protein_coding 3.2
bar=donor   line=cohort median 		5.6 5.6 20.9%
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