GSM5528531

Dataset: gse182409 • Sample: T035 • Status: Pregnancy-stage cohort
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Quality Control Metrics

65,502,222 Total counts Group median: 70,855,220 • 35.3%ile (≈ Median)
30,534 Detected genes Group median: 31,576 • 38.7%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 25.7%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

64.0Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.93
bar=donor   line=cohort median 		9.31 19.0%
CETP Lipid Metabolism 1.18
bar=donor   line=cohort median 		1.18 50.7%
SIRT6 Sirtuin Family 2.68
bar=donor   line=cohort median 		2.22 95.5%
SIRT1 Sirtuin Family 5.68
bar=donor   line=cohort median 		5.50 84.5%
SIRT3 Sirtuin Family 2.11
bar=donor   line=cohort median 		2.33 19.7%
IGF1R Insulin/IGF-1 Signaling 7.26
bar=donor   line=cohort median 		7.09 71.4%
KLOTHO Anti-aging 0.87
bar=donor   line=cohort median 		0.66 64.5%
IRS2 Insulin/IGF-1 Signaling 5.61
bar=donor   line=cohort median 		5.59 51.4%
TP53 Tumor Suppression 3.39
bar=donor   line=cohort median 		2.72 89.3%
SHC1 Signal Transduction 4.28
bar=donor   line=cohort median 		3.95 94.1%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.9 3,279,807
2 ENSG00000258486 ENSG00000258486 15.7 2,868,902
3 7SK ENSG00000202198 misc_RNA 14.4 1,110,975
4 B2M ENSG00000166710 protein_coding 13.6 668,602
5 MALAT1 ENSG00000251562 lncRNA 13.5 614,842
6 AL355075.4 ENSG00000259001 lncRNA 13.5 600,835
7 ALAS2 ENSG00000158578 protein_coding 13.5 589,964
8 BNIP3L ENSG00000104765 protein_coding 13.3 537,601
9 S100A9 ENSG00000163220 protein_coding 13.3 522,314
10 SLC25A37 ENSG00000147454 protein_coding 13.1 450,820

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.9
bar=donor   line=cohort median 		11.8 11.8 61.3%
2 S100A9 protein_coding 13.3
bar=donor   line=cohort median 		13.1 13.1 69.5%
3 IL1B protein_coding 5.7
bar=donor   line=cohort median 		6.9 6.9 4.5%
4 CXCL8 protein_coding 7.6
bar=donor   line=cohort median 		7.6 7.6 52.4%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.7
bar=donor   line=cohort median 		4.0 4.0 68.8%
6 FCGR3B protein_coding 11.9
bar=donor   line=cohort median 		11.3 11.3 86.6%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.3
bar=donor   line=cohort median 		10.9 10.9 80.5%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.0
bar=donor   line=cohort median 		5.3 5.3 16.1%
9 CD3E protein_coding 1.3
bar=donor   line=cohort median 		2.6 2.6 1.0%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.9
bar=donor   line=cohort median 		6.3 6.3 22.9%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 2.6
bar=donor   line=cohort median 		3.4 3.4 12.7%
12 GNLY protein_coding 4.8
bar=donor   line=cohort median 		4.9 4.9 47.6%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 5.0
bar=donor   line=cohort median 		6.6 6.6 14.0%
14 HBA1 protein_coding -0.7
bar=donor   line=cohort median 		2.6 2.6 7.2%
15 HBA2 protein_coding 2.8
bar=donor   line=cohort median 		5.6 5.6 13.4%
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