GSM5528532

Dataset: gse182409 • Sample: T036 • Status: Pregnancy-stage cohort
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Quality Control Metrics

86,907,882 Total counts Group median: 70,855,220 • 86.0%ile (↑ High)
28,321 Detected genes Group median: 31,576 • 17.5%ile (↓ Low)
0 Mitochondrial fraction (%) Group median: 0 • 71.6%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

33.7Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.56
bar=donor   line=cohort median 		9.31 68.6%
CETP Lipid Metabolism 0.39
bar=donor   line=cohort median 		1.18 8.6%
SIRT6 Sirtuin Family 1.83
bar=donor   line=cohort median 		2.22 9.3%
SIRT1 Sirtuin Family 5.68
bar=donor   line=cohort median 		5.50 85.9%
SIRT3 Sirtuin Family 2.03
bar=donor   line=cohort median 		2.33 10.7%
IGF1R Insulin/IGF-1 Signaling 6.83
bar=donor   line=cohort median 		7.09 25.2%
KLOTHO Anti-aging 0.79
bar=donor   line=cohort median 		0.66 59.7%
IRS2 Insulin/IGF-1 Signaling 5.50
bar=donor   line=cohort median 		5.59 40.3%
TP53 Tumor Suppression 1.96
bar=donor   line=cohort median 		2.72 7.9%
SHC1 Signal Transduction 3.79
bar=donor   line=cohort median 		3.95 21.0%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 14.0 1,084,033
2 ENSG00000258486 ENSG00000258486 13.7 865,874
3 ENSG00000265150 ENSG00000265150 13.7 843,797
4 B2M ENSG00000166710 protein_coding 13.4 716,002
5 ALAS2 ENSG00000158578 protein_coding 13.4 690,507
6 S100A9 ENSG00000163220 protein_coding 13.2 628,632
7 MALAT1 ENSG00000251562 lncRNA 13.1 586,888
8 ENSG00000138293 ENSG00000138293 13.1 559,324
9 SLC25A37 ENSG00000147454 protein_coding 13.0 546,415
10 BNIP3L ENSG00000104765 protein_coding 12.9 504,129

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.2
bar=donor   line=cohort median 		11.8 11.8 79.1%
2 S100A9 protein_coding 13.2
bar=donor   line=cohort median 		13.1 13.1 67.5%
3 IL1B protein_coding 6.8
bar=donor   line=cohort median 		6.9 6.9 46.2%
4 CXCL8 protein_coding 5.0
bar=donor   line=cohort median 		7.6 7.6 1.7%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.2
bar=donor   line=cohort median 		4.0 4.0 28.4%
6 FCGR3B protein_coding 11.5
bar=donor   line=cohort median 		11.3 11.3 61.3%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.8
bar=donor   line=cohort median 		10.9 10.9 38.7%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.6
bar=donor   line=cohort median 		5.3 5.3 81.2%
9 CD3E protein_coding 2.1
bar=donor   line=cohort median 		2.6 2.6 21.6%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.2
bar=donor   line=cohort median 		6.3 6.3 44.9%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 2.9
bar=donor   line=cohort median 		3.4 3.4 25.0%
12 GNLY protein_coding 4.7
bar=donor   line=cohort median 		4.9 4.9 38.0%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 11.9
bar=donor   line=cohort median 		6.6 6.6 93.5%
14 HBA1 protein_coding 7.5
bar=donor   line=cohort median 		2.6 2.6 96.2%
15 HBA2 protein_coding 10.6
bar=donor   line=cohort median 		5.6 5.6 92.8%
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