GSM5528537

Dataset: gse182409 • Sample: T041 • Status: Pregnancy-stage cohort
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Quality Control Metrics

53,783,187 Total counts Group median: 70,855,220 • 14.0%ile (↓ Low)
28,164 Detected genes Group median: 31,576 • 16.8%ile (↓ Low)
0 Mitochondrial fraction (%) Group median: 0 • 59.9%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

66.3Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 10.30
bar=donor   line=cohort median 		9.31 96.9%
CETP Lipid Metabolism 1.68
bar=donor   line=cohort median 		1.18 79.7%
SIRT6 Sirtuin Family 2.53
bar=donor   line=cohort median 		2.22 88.6%
SIRT1 Sirtuin Family 5.48
bar=donor   line=cohort median 		5.50 41.0%
SIRT3 Sirtuin Family 2.72
bar=donor   line=cohort median 		2.33 90.7%
IGF1R Insulin/IGF-1 Signaling 7.04
bar=donor   line=cohort median 		7.09 45.2%
KLOTHO Anti-aging 1.13
bar=donor   line=cohort median 		0.66 80.3%
IRS2 Insulin/IGF-1 Signaling 5.24
bar=donor   line=cohort median 		5.59 23.8%
TP53 Tumor Suppression 2.75
bar=donor   line=cohort median 		2.72 54.1%
SHC1 Signal Transduction 4.02
bar=donor   line=cohort median 		3.95 63.1%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 14.7 1,428,025
2 ENSG00000265150 ENSG00000265150 14.4 1,135,416
3 ENSG00000258486 ENSG00000258486 14.4 1,131,806
4 ALAS2 ENSG00000158578 protein_coding 13.6 646,464
5 AL355075.4 ENSG00000259001 lncRNA 13.4 580,044
6 B2M ENSG00000166710 protein_coding 13.4 558,620
7 MALAT1 ENSG00000251562 lncRNA 13.1 447,190
8 S100A9 ENSG00000163220 protein_coding 13.0 440,789
9 TMSB4X ENSG00000205542 protein_coding 12.5 293,562
10 SLC25A37 ENSG00000147454 protein_coding 12.4 285,595

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.9
bar=donor   line=cohort median 		11.8 11.8 59.9%
2 S100A9 protein_coding 13.0
bar=donor   line=cohort median 		13.1 13.1 43.5%
3 IL1B protein_coding 7.0
bar=donor   line=cohort median 		6.9 6.9 59.9%
4 CXCL8 protein_coding 8.1
bar=donor   line=cohort median 		7.6 7.6 68.8%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.8
bar=donor   line=cohort median 		4.0 4.0 70.2%
6 FCGR3B protein_coding 11.3
bar=donor   line=cohort median 		11.3 11.3 51.0%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.7
bar=donor   line=cohort median 		10.9 10.9 35.3%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.0
bar=donor   line=cohort median 		5.3 5.3 17.5%
9 CD3E protein_coding 1.6
bar=donor   line=cohort median 		2.6 2.6 9.2%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 7.1
bar=donor   line=cohort median 		6.3 6.3 95.5%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.2
bar=donor   line=cohort median 		3.4 3.4 39.4%
12 GNLY protein_coding 5.2
bar=donor   line=cohort median 		4.9 4.9 68.8%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 5.7
bar=donor   line=cohort median 		6.6 6.6 27.7%
14 HBA1 protein_coding 1.9
bar=donor   line=cohort median 		2.6 2.6 41.4%
15 HBA2 protein_coding 4.7
bar=donor   line=cohort median 		5.6 5.6 38.0%
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