GSM5528538

Dataset: gse182409 • Sample: T042 • Status: Pregnancy-stage cohort
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Quality Control Metrics

91,199,744 Total counts Group median: 70,855,220 • 92.1%ile (↑ High)
32,391 Detected genes Group median: 31,576 • 70.2%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 15.4%ile (↓ Low)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

52.7Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.41
bar=donor   line=cohort median 		9.31 57.6%
CETP Lipid Metabolism 0.45
bar=donor   line=cohort median 		1.18 9.3%
SIRT6 Sirtuin Family 2.12
bar=donor   line=cohort median 		2.22 39.7%
SIRT1 Sirtuin Family 5.72
bar=donor   line=cohort median 		5.50 89.3%
SIRT3 Sirtuin Family 2.60
bar=donor   line=cohort median 		2.33 87.2%
IGF1R Insulin/IGF-1 Signaling 7.05
bar=donor   line=cohort median 		7.09 46.6%
KLOTHO Anti-aging 1.07
bar=donor   line=cohort median 		0.66 74.8%
IRS2 Insulin/IGF-1 Signaling 5.22
bar=donor   line=cohort median 		5.59 22.4%
TP53 Tumor Suppression 2.42
bar=donor   line=cohort median 		2.72 33.5%
SHC1 Signal Transduction 4.05
bar=donor   line=cohort median 		3.95 66.6%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.6 3,805,829
2 ENSG00000258486 ENSG00000258486 15.6 3,651,648
3 7SK ENSG00000202198 misc_RNA 14.9 2,351,907
4 B2M ENSG00000166710 protein_coding 13.7 963,319
5 AL355075.4 ENSG00000259001 lncRNA 13.6 951,782
6 S100A9 ENSG00000163220 protein_coding 13.6 924,053
7 ALAS2 ENSG00000158578 protein_coding 13.1 672,744
8 MALAT1 ENSG00000251562 lncRNA 13.0 611,470
9 NAMPT ENSG00000105835 protein_coding 13.0 610,721
10 BNIP3L ENSG00000104765 protein_coding 12.9 559,023

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.4
bar=donor   line=cohort median 		11.8 11.8 88.7%
2 S100A9 protein_coding 13.6
bar=donor   line=cohort median 		13.1 13.1 88.7%
3 IL1B protein_coding 7.3
bar=donor   line=cohort median 		6.9 6.9 81.8%
4 CXCL8 protein_coding 8.7
bar=donor   line=cohort median 		7.6 7.6 87.3%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.4
bar=donor   line=cohort median 		4.0 4.0 64.0%
6 FCGR3B protein_coding 11.6
bar=donor   line=cohort median 		11.3 11.3 72.3%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.7
bar=donor   line=cohort median 		10.9 10.9 98.3%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.2
bar=donor   line=cohort median 		5.3 5.3 47.6%
9 CD3E protein_coding 1.9
bar=donor   line=cohort median 		2.6 2.6 16.1%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 7.0
bar=donor   line=cohort median 		6.3 6.3 93.5%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 2.7
bar=donor   line=cohort median 		3.4 3.4 16.1%
12 GNLY protein_coding 4.6
bar=donor   line=cohort median 		4.9 4.9 32.5%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 5.3
bar=donor   line=cohort median 		6.6 6.6 20.2%
14 HBA1 protein_coding -0.4
bar=donor   line=cohort median 		2.6 2.6 12.7%
15 HBA2 protein_coding 3.1
bar=donor   line=cohort median 		5.6 5.6 20.2%
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