GSM5528539

Dataset: gse182409 • Sample: T043 • Status: Pregnancy-stage cohort
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Quality Control Metrics

58,930,489 Total counts Group median: 70,855,220 • 20.2%ile (↓ Low)
28,559 Detected genes Group median: 31,576 • 18.8%ile (↓ Low)
0 Mitochondrial fraction (%) Group median: 0 • 53.1%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

27.9Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.54
bar=donor   line=cohort median 		9.31 66.6%
CETP Lipid Metabolism 0.18
bar=donor   line=cohort median 		1.18 3.8%
SIRT6 Sirtuin Family 1.92
bar=donor   line=cohort median 		2.22 15.5%
SIRT1 Sirtuin Family 5.71
bar=donor   line=cohort median 		5.50 87.2%
SIRT3 Sirtuin Family 2.00
bar=donor   line=cohort median 		2.33 7.9%
IGF1R Insulin/IGF-1 Signaling 6.63
bar=donor   line=cohort median 		7.09 11.4%
KLOTHO Anti-aging 0.54
bar=donor   line=cohort median 		0.66 35.5%
IRS2 Insulin/IGF-1 Signaling 4.92
bar=donor   line=cohort median 		5.59 10.7%
TP53 Tumor Suppression 2.13
bar=donor   line=cohort median 		2.72 14.8%
SHC1 Signal Transduction 3.81
bar=donor   line=cohort median 		3.95 25.9%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.0 1,726,986
2 ENSG00000258486 ENSG00000258486 14.9 1,628,850
3 7SK ENSG00000202198 misc_RNA 14.7 1,392,203
4 B2M ENSG00000166710 protein_coding 13.6 650,061
5 MALAT1 ENSG00000251562 lncRNA 13.6 648,625
6 ALAS2 ENSG00000158578 protein_coding 13.4 568,994
7 AL355075.4 ENSG00000259001 lncRNA 13.2 512,701
8 S100A9 ENSG00000163220 protein_coding 12.7 359,331
9 SLC25A37 ENSG00000147454 protein_coding 12.6 340,992
10 EEF1A1 ENSG00000156508 protein_coding 12.4 278,657

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.4
bar=donor   line=cohort median 		11.8 11.8 23.6%
2 S100A9 protein_coding 12.7
bar=donor   line=cohort median 		13.1 13.1 23.6%
3 IL1B protein_coding 6.4
bar=donor   line=cohort median 		6.9 6.9 23.6%
4 CXCL8 protein_coding 7.9
bar=donor   line=cohort median 		7.6 7.6 64.7%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 2.7
bar=donor   line=cohort median 		4.0 4.0 18.8%
6 FCGR3B protein_coding 11.5
bar=donor   line=cohort median 		11.3 11.3 66.1%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.4
bar=donor   line=cohort median 		10.9 10.9 86.6%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.5
bar=donor   line=cohort median 		5.3 5.3 68.2%
9 CD3E protein_coding 2.8
bar=donor   line=cohort median 		2.6 2.6 55.8%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.4
bar=donor   line=cohort median 		6.3 6.3 57.9%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 2.8
bar=donor   line=cohort median 		3.4 3.4 18.8%
12 GNLY protein_coding 4.3
bar=donor   line=cohort median 		4.9 4.9 15.4%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 5.8
bar=donor   line=cohort median 		6.6 6.6 31.2%
14 HBA1 protein_coding 3.3
bar=donor   line=cohort median 		2.6 2.6 58.6%
15 HBA2 protein_coding 6.2
bar=donor   line=cohort median 		5.6 5.6 55.8%
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