GSM5528541

Dataset: gse182409 • Sample: T045 • Status: Pregnancy-stage cohort
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Quality Control Metrics

66,523,015 Total counts Group median: 70,855,220 • 38.0%ile (≈ Median)
31,877 Detected genes Group median: 31,576 • 56.5%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 66.1%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

47.0Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.05
bar=donor   line=cohort median 		9.31 27.9%
CETP Lipid Metabolism 2.14
bar=donor   line=cohort median 		1.18 92.1%
SIRT6 Sirtuin Family 2.17
bar=donor   line=cohort median 		2.22 44.5%
SIRT1 Sirtuin Family 5.49
bar=donor   line=cohort median 		5.50 44.5%
SIRT3 Sirtuin Family 2.79
bar=donor   line=cohort median 		2.33 93.5%
IGF1R Insulin/IGF-1 Signaling 6.22
bar=donor   line=cohort median 		7.09 1.7%
KLOTHO Anti-aging 0.94
bar=donor   line=cohort median 		0.66 69.3%
IRS2 Insulin/IGF-1 Signaling 5.30
bar=donor   line=cohort median 		5.59 26.6%
TP53 Tumor Suppression 2.95
bar=donor   line=cohort median 		2.72 64.5%
SHC1 Signal Transduction 3.60
bar=donor   line=cohort median 		3.95 5.9%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.1 1,978,482
2 ENSG00000258486 ENSG00000258486 14.9 1,707,108
3 7SK ENSG00000202198 misc_RNA 14.5 1,261,264
4 AL355075.4 ENSG00000259001 lncRNA 13.4 608,634
5 MALAT1 ENSG00000251562 lncRNA 13.4 600,058
6 S100A9 ENSG00000163220 protein_coding 13.4 584,061
7 B2M ENSG00000166710 protein_coding 13.2 507,906
8 HBB ENSG00000244734 protein_coding 13.0 463,627
9 BNIP3L ENSG00000104765 protein_coding 12.8 384,616
10 NAMPT ENSG00000105835 protein_coding 12.4 302,960

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.0
bar=donor   line=cohort median 		11.8 11.8 62.7%
2 S100A9 protein_coding 13.4
bar=donor   line=cohort median 		13.1 13.1 78.4%
3 IL1B protein_coding 7.4
bar=donor   line=cohort median 		6.9 6.9 86.0%
4 CXCL8 protein_coding 8.1
bar=donor   line=cohort median 		7.6 7.6 69.5%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.2
bar=donor   line=cohort median 		4.0 4.0 59.2%
6 FCGR3B protein_coding 11.5
bar=donor   line=cohort median 		11.3 11.3 65.4%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.1
bar=donor   line=cohort median 		10.9 10.9 9.9%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 4.9
bar=donor   line=cohort median 		5.3 5.3 14.7%
9 CD3E protein_coding 3.0
bar=donor   line=cohort median 		2.6 2.6 67.5%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.8
bar=donor   line=cohort median 		6.3 6.3 17.5%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 5.1
bar=donor   line=cohort median 		3.4 3.4 98.3%
12 GNLY protein_coding 7.1
bar=donor   line=cohort median 		4.9 4.9 99.7%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 13.0
bar=donor   line=cohort median 		6.6 6.6 97.6%
14 HBA1 protein_coding 7.3
bar=donor   line=cohort median 		2.6 2.6 93.5%
15 HBA2 protein_coding 11.0
bar=donor   line=cohort median 		5.6 5.6 94.9%
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