GSM5528542

Dataset: gse182409 • Sample: T046 • Status: Pregnancy-stage cohort
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Quality Control Metrics

49,876,744 Total counts Group median: 70,855,220 • 7.2%ile (↓ Low)
30,901 Detected genes Group median: 31,576 • 42.1%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 27.7%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

59.9Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.46
bar=donor   line=cohort median 		9.31 63.1%
CETP Lipid Metabolism 0.97
bar=donor   line=cohort median 		1.18 36.2%
SIRT6 Sirtuin Family 2.68
bar=donor   line=cohort median 		2.22 94.8%
SIRT1 Sirtuin Family 5.43
bar=donor   line=cohort median 		5.50 32.8%
SIRT3 Sirtuin Family 2.17
bar=donor   line=cohort median 		2.33 25.9%
IGF1R Insulin/IGF-1 Signaling 7.19
bar=donor   line=cohort median 		7.09 61.0%
KLOTHO Anti-aging 1.08
bar=donor   line=cohort median 		0.66 76.9%
IRS2 Insulin/IGF-1 Signaling 5.57
bar=donor   line=cohort median 		5.59 45.9%
TP53 Tumor Suppression 3.12
bar=donor   line=cohort median 		2.72 74.8%
SHC1 Signal Transduction 4.24
bar=donor   line=cohort median 		3.95 87.9%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.3 1,783,404
2 ENSG00000258486 ENSG00000258486 15.2 1,637,560
3 7SK ENSG00000202198 misc_RNA 14.9 1,279,906
4 MALAT1 ENSG00000251562 lncRNA 13.6 550,752
5 S100A9 ENSG00000163220 protein_coding 13.5 510,459
6 B2M ENSG00000166710 protein_coding 13.5 510,329
7 AL355075.4 ENSG00000259001 lncRNA 13.5 486,279
8 NAMPT ENSG00000105835 protein_coding 13.3 428,546
9 ALAS2 ENSG00000158578 protein_coding 12.9 337,399
10 BNIP3L ENSG00000104765 protein_coding 12.9 326,300

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.2
bar=donor   line=cohort median 		11.8 11.8 86.6%
2 S100A9 protein_coding 13.5
bar=donor   line=cohort median 		13.1 13.1 86.6%
3 IL1B protein_coding 5.3
bar=donor   line=cohort median 		6.9 6.9 1.0%
4 CXCL8 protein_coding 9.3
bar=donor   line=cohort median 		7.6 7.6 95.5%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 5.5
bar=donor   line=cohort median 		4.0 4.0 88.0%
6 FCGR3B protein_coding 11.9
bar=donor   line=cohort median 		11.3 11.3 90.8%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.4
bar=donor   line=cohort median 		10.9 10.9 16.8%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.4
bar=donor   line=cohort median 		5.3 5.3 59.9%
9 CD3E protein_coding 2.0
bar=donor   line=cohort median 		2.6 2.6 19.5%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.1
bar=donor   line=cohort median 		6.3 6.3 37.3%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 2.3
bar=donor   line=cohort median 		3.4 3.4 5.1%
12 GNLY protein_coding 4.9
bar=donor   line=cohort median 		4.9 4.9 51.7%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 9.2
bar=donor   line=cohort median 		6.6 6.6 79.8%
14 HBA1 protein_coding 4.0
bar=donor   line=cohort median 		2.6 2.6 66.8%
15 HBA2 protein_coding 6.9
bar=donor   line=cohort median 		5.6 5.6 64.0%
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