GSM5528544

Dataset: gse182409 • Sample: T048 • Status: Pregnancy-stage cohort
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Quality Control Metrics

78,947,549 Total counts Group median: 70,855,220 • 68.8%ile (≈ Median)
34,560 Detected genes Group median: 31,576 • 97.6%ile (↑ High)
0 Mitochondrial fraction (%) Group median: 0 • 75.0%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

51.1Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.56
bar=donor   line=cohort median 		9.31 67.9%
CETP Lipid Metabolism 0.39
bar=donor   line=cohort median 		1.18 7.9%
SIRT6 Sirtuin Family 2.61
bar=donor   line=cohort median 		2.22 92.1%
SIRT1 Sirtuin Family 5.52
bar=donor   line=cohort median 		5.50 56.9%
SIRT3 Sirtuin Family 2.29
bar=donor   line=cohort median 		2.33 46.6%
IGF1R Insulin/IGF-1 Signaling 7.28
bar=donor   line=cohort median 		7.09 75.5%
KLOTHO Anti-aging 0.55
bar=donor   line=cohort median 		0.66 37.6%
IRS2 Insulin/IGF-1 Signaling 6.25
bar=donor   line=cohort median 		5.59 93.5%
TP53 Tumor Suppression 1.77
bar=donor   line=cohort median 		2.72 1.7%
SHC1 Signal Transduction 3.83
bar=donor   line=cohort median 		3.95 31.4%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 14.6 2,003,279
2 7SK ENSG00000202198 misc_RNA 14.4 1,764,156
3 ENSG00000258486 ENSG00000258486 14.4 1,743,745
4 MALAT1 ENSG00000251562 lncRNA 13.9 1,239,668
5 S100A9 ENSG00000163220 protein_coding 13.2 757,811
6 AL355075.4 ENSG00000259001 lncRNA 13.2 738,100
7 B2M ENSG00000166710 protein_coding 13.1 698,900
8 NAMPT ENSG00000105835 protein_coding 12.8 565,867
9 NEAT1 ENSG00000245532 lncRNA 12.7 515,529
10 SORL1 ENSG00000137642 protein_coding 12.3 390,945

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.0
bar=donor   line=cohort median 		11.8 11.8 68.2%
2 S100A9 protein_coding 13.2
bar=donor   line=cohort median 		13.1 13.1 59.9%
3 IL1B protein_coding 7.1
bar=donor   line=cohort median 		6.9 6.9 68.2%
4 CXCL8 protein_coding 8.4
bar=donor   line=cohort median 		7.6 7.6 79.8%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 5.4
bar=donor   line=cohort median 		4.0 4.0 87.3%
6 FCGR3B protein_coding 11.3
bar=donor   line=cohort median 		11.3 11.3 45.5%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.5
bar=donor   line=cohort median 		10.9 10.9 90.1%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 4.8
bar=donor   line=cohort median 		5.3 5.3 9.9%
9 CD3E protein_coding 2.5
bar=donor   line=cohort median 		2.6 2.6 45.5%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.7
bar=donor   line=cohort median 		6.3 6.3 77.1%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.3
bar=donor   line=cohort median 		3.4 3.4 40.1%
12 GNLY protein_coding 4.8
bar=donor   line=cohort median 		4.9 4.9 44.2%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 6.1
bar=donor   line=cohort median 		6.6 6.6 38.0%
14 HBA1 protein_coding 0.5
bar=donor   line=cohort median 		2.6 2.6 27.1%
15 HBA2 protein_coding 4.4
bar=donor   line=cohort median 		5.6 5.6 36.0%
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