GSM5528545

Dataset: gse182409 • Sample: T049 • Status: Pregnancy-stage cohort
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Quality Control Metrics

69,190,671 Total counts Group median: 70,855,220 • 45.5%ile (≈ Median)
33,134 Detected genes Group median: 31,576 • 83.9%ile (↑ High)
0 Mitochondrial fraction (%) Group median: 0 • 66.8%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

64.0Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.69
bar=donor   line=cohort median 		9.31 8.6%
CETP Lipid Metabolism 1.57
bar=donor   line=cohort median 		1.18 73.5%
SIRT6 Sirtuin Family 2.23
bar=donor   line=cohort median 		2.22 52.1%
SIRT1 Sirtuin Family 5.67
bar=donor   line=cohort median 		5.50 81.7%
SIRT3 Sirtuin Family 2.51
bar=donor   line=cohort median 		2.33 78.3%
IGF1R Insulin/IGF-1 Signaling 7.33
bar=donor   line=cohort median 		7.09 76.2%
KLOTHO Anti-aging 0.71
bar=donor   line=cohort median 		0.66 54.1%
IRS2 Insulin/IGF-1 Signaling 6.13
bar=donor   line=cohort median 		5.59 90.0%
TP53 Tumor Suppression 2.98
bar=donor   line=cohort median 		2.72 69.3%
SHC1 Signal Transduction 3.99
bar=donor   line=cohort median 		3.95 56.2%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 14.8 1,757,611
2 ENSG00000258486 ENSG00000258486 14.7 1,677,552
3 7SK ENSG00000202198 misc_RNA 14.3 1,230,126
4 ALAS2 ENSG00000158578 protein_coding 13.7 812,117
5 MALAT1 ENSG00000251562 lncRNA 13.3 641,618
6 B2M ENSG00000166710 protein_coding 13.2 606,136
7 SLC25A37 ENSG00000147454 protein_coding 13.0 522,654
8 AL355075.4 ENSG00000259001 lncRNA 12.9 470,729
9 S100A9 ENSG00000163220 protein_coding 12.8 464,175
10 TENT5C ENSG00000183508 protein_coding 12.8 444,308

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.7
bar=donor   line=cohort median 		11.8 11.8 40.8%
2 S100A9 protein_coding 12.8
bar=donor   line=cohort median 		13.1 13.1 31.8%
3 IL1B protein_coding 7.2
bar=donor   line=cohort median 		6.9 6.9 73.6%
4 CXCL8 protein_coding 7.8
bar=donor   line=cohort median 		7.6 7.6 59.2%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 2.8
bar=donor   line=cohort median 		4.0 4.0 20.2%
6 FCGR3B protein_coding 11.3
bar=donor   line=cohort median 		11.3 11.3 49.7%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.0
bar=donor   line=cohort median 		10.9 10.9 54.5%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 4.9
bar=donor   line=cohort median 		5.3 5.3 15.4%
9 CD3E protein_coding 2.9
bar=donor   line=cohort median 		2.6 2.6 64.7%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 7.1
bar=donor   line=cohort median 		6.3 6.3 96.2%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.3
bar=donor   line=cohort median 		3.4 3.4 45.5%
12 GNLY protein_coding 4.3
bar=donor   line=cohort median 		4.9 4.9 18.2%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 5.9
bar=donor   line=cohort median 		6.6 6.6 35.3%
14 HBA1 protein_coding -0.4
bar=donor   line=cohort median 		2.6 2.6 16.1%
15 HBA2 protein_coding 3.3
bar=donor   line=cohort median 		5.6 5.6 23.6%
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