GSM5528546

Dataset: gse182409 • Sample: T050 • Status: Pregnancy-stage cohort
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Quality Control Metrics

100,462,697 Total counts Group median: 70,855,220 • 96.2%ile (↑ High)
32,155 Detected genes Group median: 31,576 • 64.0%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 20.2%ile (↓ Low)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

67.1Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 10.04
bar=donor   line=cohort median 		9.31 92.8%
CETP Lipid Metabolism 1.18
bar=donor   line=cohort median 		1.18 50.0%
SIRT6 Sirtuin Family 2.26
bar=donor   line=cohort median 		2.22 57.6%
SIRT1 Sirtuin Family 5.65
bar=donor   line=cohort median 		5.50 79.7%
SIRT3 Sirtuin Family 3.08
bar=donor   line=cohort median 		2.33 99.0%
IGF1R Insulin/IGF-1 Signaling 7.03
bar=donor   line=cohort median 		7.09 43.8%
KLOTHO Anti-aging -0.84
bar=donor   line=cohort median 		0.66 1.7%
IRS2 Insulin/IGF-1 Signaling 5.88
bar=donor   line=cohort median 		5.59 77.6%
TP53 Tumor Suppression 3.17
bar=donor   line=cohort median 		2.72 76.9%
SHC1 Signal Transduction 4.27
bar=donor   line=cohort median 		3.95 92.1%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.6 4,224,819
2 ENSG00000258486 ENSG00000258486 15.0 2,736,920
3 7SK ENSG00000202198 misc_RNA 14.6 2,082,686
4 ALAS2 ENSG00000158578 protein_coding 14.1 1,492,710
5 AL355075.4 ENSG00000259001 lncRNA 13.7 1,137,672
6 B2M ENSG00000166710 protein_coding 13.6 1,077,917
7 S100A9 ENSG00000163220 protein_coding 13.3 849,075
8 MALAT1 ENSG00000251562 lncRNA 13.2 799,589
9 ENSG00000138293 ENSG00000138293 13.1 752,870
10 SLC25A37 ENSG00000147454 protein_coding 13.0 705,967

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.9
bar=donor   line=cohort median 		11.8 11.8 60.6%
2 S100A9 protein_coding 13.3
bar=donor   line=cohort median 		13.1 13.1 72.3%
3 IL1B protein_coding 7.0
bar=donor   line=cohort median 		6.9 6.9 59.2%
4 CXCL8 protein_coding 8.0
bar=donor   line=cohort median 		7.6 7.6 66.1%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.1
bar=donor   line=cohort median 		4.0 4.0 53.1%
6 FCGR3B protein_coding 11.6
bar=donor   line=cohort median 		11.3 11.3 70.9%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.2
bar=donor   line=cohort median 		10.9 10.9 72.9%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.1
bar=donor   line=cohort median 		5.3 5.3 22.9%
9 CD3E protein_coding 2.2
bar=donor   line=cohort median 		2.6 2.6 30.5%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.9
bar=donor   line=cohort median 		6.3 6.3 88.7%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 2.4
bar=donor   line=cohort median 		3.4 3.4 7.9%
12 GNLY protein_coding 4.6
bar=donor   line=cohort median 		4.9 4.9 30.5%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 4.8
bar=donor   line=cohort median 		6.6 6.6 9.9%
14 HBA1 protein_coding -0.8
bar=donor   line=cohort median 		2.6 2.6 5.8%
15 HBA2 protein_coding 2.7
bar=donor   line=cohort median 		5.6 5.6 9.9%
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