GSM5528548

Dataset: gse182409 • Sample: T052 • Status: Pregnancy-stage cohort
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Quality Control Metrics

71,148,417 Total counts Group median: 70,855,220 • 51.7%ile (≈ Median)
32,185 Detected genes Group median: 31,576 • 64.7%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 12.7%ile (↓ Low)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

44.6Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 10.27
bar=donor   line=cohort median 		9.31 96.2%
CETP Lipid Metabolism 0.95
bar=donor   line=cohort median 		1.18 34.8%
SIRT6 Sirtuin Family 1.86
bar=donor   line=cohort median 		2.22 13.5%
SIRT1 Sirtuin Family 5.58
bar=donor   line=cohort median 		5.50 65.9%
SIRT3 Sirtuin Family 2.95
bar=donor   line=cohort median 		2.33 96.2%
IGF1R Insulin/IGF-1 Signaling 6.87
bar=donor   line=cohort median 		7.09 28.6%
KLOTHO Anti-aging 0.44
bar=donor   line=cohort median 		0.66 30.0%
IRS2 Insulin/IGF-1 Signaling 5.49
bar=donor   line=cohort median 		5.59 38.3%
TP53 Tumor Suppression 2.20
bar=donor   line=cohort median 		2.72 18.3%
SHC1 Signal Transduction 3.80
bar=donor   line=cohort median 		3.95 24.5%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.4 2,700,078
2 ENSG00000258486 ENSG00000258486 15.2 2,378,757
3 7SK ENSG00000202198 misc_RNA 14.8 1,838,023
4 B2M ENSG00000166710 protein_coding 13.7 862,519
5 AL355075.4 ENSG00000259001 lncRNA 13.4 692,304
6 MALAT1 ENSG00000251562 lncRNA 13.2 591,373
7 S100A9 ENSG00000163220 protein_coding 13.1 566,306
8 ALAS2 ENSG00000158578 protein_coding 13.1 559,575
9 NAMPT ENSG00000105835 protein_coding 12.7 426,781
10 SLC25A37 ENSG00000147454 protein_coding 12.6 398,849

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.9
bar=donor   line=cohort median 		11.8 11.8 56.5%
2 S100A9 protein_coding 13.1
bar=donor   line=cohort median 		13.1 13.1 53.1%
3 IL1B protein_coding 7.2
bar=donor   line=cohort median 		6.9 6.9 74.3%
4 CXCL8 protein_coding 8.4
bar=donor   line=cohort median 		7.6 7.6 81.2%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.3
bar=donor   line=cohort median 		4.0 4.0 30.5%
6 FCGR3B protein_coding 11.9
bar=donor   line=cohort median 		11.3 11.3 90.1%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.2
bar=donor   line=cohort median 		10.9 10.9 76.4%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 6.0
bar=donor   line=cohort median 		5.3 5.3 94.9%
9 CD3E protein_coding 2.4
bar=donor   line=cohort median 		2.6 2.6 38.7%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.9
bar=donor   line=cohort median 		6.3 6.3 90.1%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.1
bar=donor   line=cohort median 		3.4 3.4 33.2%
12 GNLY protein_coding 5.2
bar=donor   line=cohort median 		4.9 4.9 72.9%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 7.7
bar=donor   line=cohort median 		6.6 6.6 64.0%
14 HBA1 protein_coding 1.1
bar=donor   line=cohort median 		2.6 2.6 32.5%
15 HBA2 protein_coding 3.8
bar=donor   line=cohort median 		5.6 5.6 29.1%
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